Search Results - "Fujita, Issei"

A Mannosylated, PEGylated Albumin as a Drug Delivery System for the Treatment of Cancer Stroma Cells by Mizuta, Yuki, Maeda, Hitoshi, Ishima, Yu, Minayoshi, Yuki, Ichimizu, Shota, Kinoshita, Ryo, Fujita, Issei, Kai, Takuma, Hirata, Kenshiro, Nakamura, Teruya, Saruwatari, Junji, Arima, Hidetoshi, Watanabe, Hiroshi, Otagiri, Masaki, Maruyama, Toru

“…Mannose receptors that are expressed on macrophages and fibroblasts in cancer stroma are promising therapeutic targets for cancer treatment. Albumin can be…”
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Indoxyl Sulfate Contributes to mTORC1-Induced Renal Fibrosis via The OAT/NADPH Oxidase/ROS Pathway by Nakano, Takehiro, Watanabe, Hiroshi, Imafuku, Tadashi, Tokumaru, Kai, Fujita, Issei, Arimura, Nanaka, Maeda, Hitoshi, Tanaka, Motoko, Matsushita, Kazutaka, Fukagawa, Masafumi, Maruyama, Toru

“…Activation of mTORC1 (mechanistic target of rapamycin complex 1) in renal tissue has been reported in chronic kidney disease (CKD)-induced renal fibrosis…”
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Evaluation for Blood Concentration and Efficacy/Safety of Continuous Administration of Thiamylal in Children by Hirata, Kenshiro, Obara, Takafumi, Ikeda, Tokunori, Watanabe, Hiroshi, Fujita, Issei, Furusho, Hirokazu, Ishiguro, Takako, Jingami, Sachiko, Maruyama, Toru, Hirai, Katsuki, Miyamura, Shigeyuki

“…Thiamylal exerts excellent sedative effects. However, it is not routinely used because of its serious adverse effects. This study aimed to clarify the target…”
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Advanced oxidation protein products contribute to chronic kidney disease‐induced muscle atrophy by inducing oxidative stress via CD36/NADPH oxidase pathway by Kato, Hiromasa, Watanabe, Hiroshi, Imafuku, Tadashi, Arimura, Nanaka, Fujita, Issei, Noguchi, Isamu, Tanaka, Shoma, Nakano, Takehiro, Tokumaru, Kai, Enoki, Yuki, Maeda, Hitoshi, Hino, Shinjiro, Tanaka, Motoko, Matsushita, Kazutaka, Fukagawa, Masafumi, Maruyama, Toru

“…Background Sarcopenia with chronic kidney disease (CKD) progression is associated with life prognosis. Oxidative stress has attracted interest as a trigger for…”
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Charging potential measurement of floating electrode modeled on the arc shield of vacuum interrupter under AC voltage application by Fukuda, Hideaki, Yamamura, Kenta, Fujita, Issei, Kusa, Ryutaro, Yamano, Yasushi

“…A charging potential of a floating electrode modeled on vacuum interrupter was measured under unipolar AC voltage application using a surface potential meter…”
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Contribution of the α 1 -Acid Glycoprotein in Drug Pharmacokinetics: The Usefulness of α 1 -Acid Glycoprotein-Knockout Mice by Nakamura, Yuka, Watanabe, Hiroshi, Imafuku, Tadashi, Fujita, Issei, Ganaha, Yuto, Takeo, Toru, Nakagata, Naomi, Maeda, Hitoshi, Maruyama, Toru

“…α -Acid glycoprotein (AGP) is a primary binding protein for many basic drugs in plasma. The number of drugs that bind to AGP, such as molecular target…”
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Contribution of the α1‑Acid Glycoprotein in Drug Pharmacokinetics: The Usefulness of α1‑Acid Glycoprotein-Knockout Mice by Nakamura, Yuka, Watanabe, Hiroshi, Imafuku, Tadashi, Fujita, Issei, Ganaha, Yuto, Takeo, Toru, Nakagata, Naomi, Maeda, Hitoshi, Maruyama, Toru

“…α1-Acid glycoprotein (AGP) is a primary binding protein for many basic drugs in plasma. The number of drugs that bind to AGP, such as molecular target…”
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Cystamine-mediated inhibition of protein disulfide isomerase triggers aggregation of misfolded orexin-A in the Golgi apparatus and prevents extracellular secretion of orexin-A by Fujita, Issei, Nobunaga, Mizuki, Seki, Takahiro, Kurauchi, Yuki, Hisatsune, Akinori, Katsuki, Hiroshi

“…Orexins (orexin-A and orexin-B) are neuropeptides that are reduced in narcolepsy, a sleep disorder that is characterized by excessive daytime sleepiness,…”
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Involvement of the Parathyroid Hormone-Related Protein on Changes in the CYP3A Expression in Cancer Cachexia by Fujita, Issei, Watanabe, Hiroshi, Ikegami, Komei, Imafuku, Tadashi, Ichimizu, Shota, Chikamatsu, Mayuko, Kobayashi, Kazuki, Tanaka, Ryusei, Yamada, Koichi, Maeda, Hitoshi, Maruyama, Toru

“…Parathyroid hormone-related protein (PTHrP), which is secreted from a tumor, contributes to the progression of cachexia, a condition that is observed in half…”
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Cysteinylated Albumin as a Potential Biomarker for the Progression of Kidney Disease in Patients With Type 2 Diabetes by Imafuku, Tadashi, Watanabe, Hiroshi, Oniki, Kentaro, Yoshida, Akira, Kato, Hiromasa, Nakano, Takehiro, Tokumaru, Kai, Fujita, Issei, Arimura, Nanaka, Maeda, Hitoshi, Sakamoto, Yuki, Kondo, Nozomi, Morita, Ayami, Saruwatari, Junji, Tanaka, Motoko, Matsushita, Kazutaka, Wada, Takashi, Fukagawa, Masafumi, Otagiri, Masaki, Fitzgerald, Michael L, Jinnouchi, Hideaki, Maruyama, Toru

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Charge Distribution and Charging Characteristics of Cylindrical Alumina Insulator with Shield Rings in Vacuum by Fukuda, Hideaki, Fujita, Issei, Yamano, Yasushi, Yamamura, Kenta, Yamamoto, Osamu

“…This paper deals with charging characteristics on the insulator surface in vacuum after the AC voltage application. In designing Vacuum Interrupters (VIs)…”
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Influence of Field Relaxation Ring Length on Vacuum Flashover Voltage in Model Sample of Vacuum Interrupter by Kusa, Ryutaro, Fujita, Issei, Yamano, Yasushi, Fukuda, Hideaki, Yamamura, Kenta

“…In a vacuum interrupter (VI), surface flashover events are one of the obstacles for improving its higher voltage performance. To suppress the vacuum flashover…”
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Fundamental Study on Charging Potential of Floating Electrode Modeled on Vacuum Interrupter under AC Voltage Application by Fukuda, Hideaki, Yamamura, Kenta, Kusa, Ryutaro, Fujita, Issei, Yamano, Yasushi

“…This paper is described on the charging characteristics of floating electrode modeled on Vacuum Interrupter (VI). The experimental sample has a floating…”
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Measurement of charge distibutions inside of cylindrical alumina insulator with shield rings after repeating AC voltage application by Fujita, Issei, Yamano, Yasushi, Fukuda, Hideaki, Ishikawa, Keita, Sano, Akira, Yamamoto, Osamu

“…In vacuum devices such as vacuum interrupters (VIs), surface flashover events are one of the obstacles for developing their higher performance. It is believed…”
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