Postoperative Psychiatric Complications in Living Liver Donors

Abstract Background To understand the impact of psychologic variables on donor quality of life, we studied long-term data on postoperative psychiatric complications in living liver donors. This study is a focused psychological investigation of diagnoses, treatments, and long-term clinical courses of...

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Published in:	Transplantation proceedings Vol. 47; no. 6; pp. 1860 - 1865
Main Authors:	Kimura, H, Onishi, Y, Sunada, S, Kishi, S, Suzuki, N, Tsuboi, C, Yamaguchi, N, Imai, H, Kamei, H, Fujisiro, H, Okada, T, Ishigami, M, Ogura, Y, Kiuchi, T, Ozaki, N
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-07-2015
Subjects:	Adult Depressive Disorder, Major - epidemiology Depressive Disorder, Major - etiology Female Hepatectomy - psychology Humans Incidence Japan - epidemiology Liver Transplantation - adverse effects Living Donors - psychology Male Middle Aged Postoperative Complications - epidemiology Postoperative Complications - etiology Quality of Life Surgery Young Adult Japan
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Summary:	Abstract Background To understand the impact of psychologic variables on donor quality of life, we studied long-term data on postoperative psychiatric complications in living liver donors. This study is a focused psychological investigation of diagnoses, treatments, and long-term clinical courses of living liver donors with psychiatric complications. Methods Of the 142 donors who underwent live-donor liver transplantation at Nagoya University Hospital between April 2004 and July 2014, we investigated those without a history of mental illness who had developed such illness after transplantation and required psychiatric treatment. Results A total of 6 (4.2%) donors developed the following psychiatric complications after transplantation: major depressive disorder (n = 2), panic disorder (n = 2), conversion disorder (n = 1), and substance use disorder (n = 1). Concerning psychiatric treatment, all donors received antianxiety drugs, 3 took antidepressants, and supportive psychiatric therapy was concomitantly provided to all subjects. The average treatment period was 53.3 months. Regarding subject outcomes, 3 donors achieved remission, and the other 3 continued treatment. All subjects showed improvement in Global Assessment of Functioning Scale. Conclusion It is important to accurately diagnose postoperative psychiatric complications and provide long-term treatment in close coordination with transplant surgeons.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0041-1345 1873-2623
DOI:	10.1016/j.transproceed.2015.06.021