Search Results - "Fujise, Kenshiro"
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Centronuclear Myopathy Caused by Defective Membrane Remodelling of Dynamin 2 and BIN1 Variants
Published in International journal of molecular sciences (03-06-2022)“…Centronuclear myopathy (CNM) is a congenital myopathy characterised by centralised nuclei in skeletal myofibers. T-tubules, sarcolemmal invaginations required…”
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2
Dynamin 2 and BAR domain protein pacsin 2 cooperatively regulate formation and maturation of podosomes
Published in Biochemical and biophysical research communications (24-09-2021)“…Podosomes are actin-rich adhesion structures formed in a variety of cell types, such as monocytic cells or cancer cells, to facilitate attachment to and…”
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Internalization of AMPA-type Glutamate Receptor in the MIN6 Pancreatic β-cell Line
Published in Cell Structure and Function (01-01-2020)“…The activity of AMPA-type glutamate receptor is involved in insulin release from pancreatic β-cells. However, the mechanism and dynamics that underlie AMPA…”
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Roles for primary cilia in synapses and neurological disorders
Published in Trends in cell biology (01-11-2024)Get full text
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Parkinsonism Sac domain mutation in Synaptojanin-1 affects ciliary properties in iPSC-derived dopaminergic neurons
Published in Proceedings of the National Academy of Sciences - PNAS (23-04-2024)“…Synaptojanin-1 (SJ1) is a major neuronal-enriched PI(4, 5)P 4- and 5-phosphatase implicated in the shedding of endocytic factors during endocytosis. A mutation…”
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Mutant BIN1-Dynamin 2 complexes dysregulate membrane remodeling in the pathogenesis of centronuclear myopathy
Published in The Journal of biological chemistry (01-01-2021)“…Membrane remodeling is required for dynamic cellular processes such as cell division, polarization, and motility. BAR domain proteins and dynamins are key…”
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7
Imaging‐based evaluation of pathogenicity by novel DNM2 variants associated with centronuclear myopathy
Published in Human mutation (01-02-2022)“…A centronuclear myopathy (CNM) is a group of inherited congenital diseases showing clinically progressive muscle weakness associated with the presence of…”
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Overlapping role of synaptophysin and synaptogyrin family proteins in determining the small size of synaptic vesicles
Published in Proceedings of the National Academy of Sciences - PNAS (16-07-2024)“…Members of the synaptophysin and synaptogyrin family are vesicle proteins with four transmembrane domains. In spite of their abundance in synaptic vesicle (SV)…”
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Phosphorylation of cortactin by cyclin-dependent kinase 5 modulates actin bundling by the dynamin 1-cortactin ring-like complex and formation of filopodia and lamellipodia in NG108-15 glioma-derived cells
Published in International journal of oncology (01-02-2019)“…Dynamin copolymerizes with cortactin to form a ring‑like complex that bundles and stabilizes actin filaments. Actin bundle formation is crucial for generation…”
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[Corrigendum]Phosphorylation of cortactin by cyclin-dependent kinase 5 modulates actin bundling by the dynamin 1-cortactin ring-like complex and formation of filopodia and lamellipodia in NG108-15 glioma-derived cells
Published in International journal of oncology (01-03-2020)Get full text
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11
Internalization of AMPA-type glutamate receptor in the MIN6 pancreatic β-cell line
Published in Cell Structure and Function (2020)“…The activity of AMPA-type glutamate receptor is involved in insulin release from pancreatic β-cells. However, the mechanism and dynamics that underlie AMPA…”
Get full text
Journal Article -
12
Mutant BIN1-Dynamin 2 complexes dysregulate membrane remodeling in the pathogenesis of centronuclear myopathy
Published in The Journal of biological chemistry (21-11-2020)“…Membrane remodeling is required for dynamic cellular processes such as cell division, polarization, and motility. BAR domain proteins and dynamins are key…”
Get full text
Journal Article