Search Results - "Fujisawa, Shinya"

Atorvastatin-induced anemia accompanied by elevated serum LDH levels by Fujisawa, Shinya, Fukatsu, Yusuke, Sugimoto, Yuya

“…A 68-year-old woman consulted us because of anemia and elevated LDH serum levels >1,000 U/l. No particular disease was observed by various screening tests…”
Get more information

Down-regulation of Thanatos-associated protein 11 by BCR-ABL promotes CML cell proliferation through c-Myc expression by Nakamura, Satoki, Yokota, Daisuke, Tan, Lin, Nagata, Yasuyuki, Takemura, Tomonari, Hirano, Isao, Shigeno, Kazuyuki, Shibata, Kiyoshi, Fujisawa, Shinya, Ohnishi, Kazunori

“…Bcr‐Abl activates various signaling pathways in chronic myelogenous leukemia (CML) cells. The proliferation of Bcr‐Abl transformed cells is promoted by c‐Myc…”
Get full text

Transcriptional repression of Cdc25B by IER5 inhibits the proliferation of leukemic progenitor cells through NF-YB and p300 in acute myeloid leukemia by Nakamura, Satoki, Nagata, Yasuyuki, Tan, Lin, Takemura, Tomonari, Shibata, Kiyoshi, Fujie, Michio, Fujisawa, Shinya, Tanaka, Yasutaka, Toda, Mitsuo, Makita, Reiko, Tsunekawa, Kenji, Yamada, Manabu, Yamaoka, Mayumi, Yamashita, Junko, Ohnishi, Kazunori, Yamashita, Mitsuji

“…The immediately-early response gene 5 (IER5) has been reported to be induced by γ-ray irradiation and to play a role in the induction of cell death caused by…”
Get full text

JmjC-domain containing histone demethylase 1B-mediated p15Ink4b suppression promotes the proliferation of leukemic progenitor cells through modulation of cell cycle progression in acute myeloid leukemia by Nakamura, Satoki, Tan, Lin, Nagata, Yasuyuki, Takemura, Tomonari, Asahina, Aya, Yokota, Daisuke, Yagyu, Tomohiro, Shibata, Kiyoshi, Fujisawa, Shinya, Ohnishi, Kazunori

“…The histone demethylase JHDM1B has been implicated in cell cycle regulation and tumorigenesis. In addition, it has been reported that JHDM1B is highly…”
Get full text

A variant transcript, e1a3, of the minor BCR–ABL fusion gene in acute lymphoblastic leukemia: case report and review of the literature by Fujisawa, Shinya, Nakamura, Satoki, Naito, Kensuke, Kobayashi, Masahide, Ohnishi, Kazunori

“…We report a rare case of adult Philadelphia chromosome (Ph)-positive acute lymphoblastic leukemia (ALL) with an e1a3 fusion transcript. A 25-year-old female…”
Get full text

Depletion of Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatases 1 and 2 by Bcr-Abl Promotes Chronic Myelogenous Leukemia Cell Proliferation through Continuous Phosphorylation of Akt Isoforms by Hirano, Isao, Nakamura, Satoki, Yokota, Daisuke, Ono, Takaaki, Shigeno, Kazuyuki, Fujisawa, Shinya, Shinjo, Kaori, Ohnishi, Kazunori

“…The constitutive activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway commonly occurs in cancers and is a crucial event in tumorigenesis. Chronic…”
Get full text

Reduction of Raf Kinase Inhibitor Protein Expression by Bcr-Abl Contributes to Chronic Myelogenous Leukemia Proliferation by Takemura, Tomonari, Nakamura, Satoki, Yokota, Daisuke, Hirano, Isao, Ono, Takaaki, Shigeno, Kazuyuki, Fujisawa, Shinya, Ohnishi, Kazunori

“…Chronic myelogenous leukemia (CML) is characterized by a reciprocal chromosomal translocation (9;22) that generates the Bcr-Abl fusion gene. The…”
Get full text

Clinicopathological and prognostic characteristics of CD56‐negative multiple myeloma by Sahara, Naohi, Takeshita, Akihiro, Shigeno, Kazuyuki, Fujisawa, Shinya, Takeshita, Kaori, Naito, Kensuke, Ihara, Michio, Ono, Takaaki, Tamashima, Sadahiro, Nara, Kenji, Ohnishi, Kazunori, Ohno, Ryuzo

“…We analysed CD56 expression in 70 patients with multiple myeloma (MM) to determine its clinicopathological and prognostic significance. Fifty‐five (79%)…”
Get full text

Complete remission induced by gemtuzumab ozogamicin in a Jehovah's witness patient with acute myelogenous Leukemia by FUJISAWA, Shinya, NAITO, Kensuke, MATSUOKA, Toshihiko, KOBAYASHI, Masahide

“…We report an interesting case of acute myelogenous leukemia (AML) in a Jehovah's Witness patient. A 61-year-old woman, a Jehovah's Witness, consulted our…”
Get full text

CD5+ diffuse large B-cell lymphoma with c-myc/IgH rearrangement presenting as primary effusion lymphoma by Fujisawa, Shinya, Tanioka, Fumihiko, Matsuoka, Toshihiko, Ozawa, Takachika

“…We report an instructive case of diffuse large B-cell lymphoma presenting as acute heart failure. A 69-year-old human immunodeficiency virus-negative man was…”
Get full text

CD7/CD19 double-positive T-cell acute lymphoblastic leukemia by FUJISAWA, Shinya, TANIOKA, Fumihiko, MATSUOKA, Toshihiko, OZAWA, Takachika, NAITO, Kensuke, KOBAYASHI, Masahide

“…We report a rare case of T-cell acute lymphoblastic leukemia (T-ALL) with an aberrant phenotype. A 52-year-old man was admitted to our hospital because of…”
Get full text

KIS induces proliferation and the cell cycle progression through the phosphorylation of p27Kip1 in leukemia cells by Nakamura, Satoki, Okinaka, Keiji, Hirano, Isao, Ono, Takaaki, Sugimoto, Yuya, Shigeno, Kazuyuki, Fujisawa, Shinya, Shinjo, Kaori, Ohnishi, Kazunori

“…CEM, MOLT4 and SUP-B15 cells were transduced with lentivirus-mediated siRNA KIS gene. The mRNA expressions of KIS were successfully reduced in all cell lines…”
Get full text

Reversed clinicopathological conference (R-CPC)--interpreting laboratory data in the same way as physical findings by Sugano, Mitsutoshi, Shimada, Masashi, Moriyoshi, Miho, Kitagawa, Kiyoki, Nakashima, Hiromi, Wada, Hideo, Yanagihara, Katsunori, Fujisawa, Shinya, Yonekawa, Osamu, Honda, Takayuki

“…Routine laboratory data are discussed by time series analysis in reversed clinicopathological conferences (R-CPC) at Shinshu University School of Medicine. We…”
Get more information

Recognition of the importance of reversed CPC in CPC by Kanai, Shinichiro, Matsumoto, Go, Sano, Kenji, Ueda, Kazuhiko, Fujisawa, Shinya, Obayashi, Konen, Hashiguchi, Teruto, Yanagihara, Katsunori, Moriyoshi, Miho, Kitagawa, Kiyoki, Wada, Hideo, Morinobu, Akio, Wada, Takashi, Honda, Takayuki

“…Clinicopathological conferences (CPC) are one of the most important clinical conferences, and processes of both diagnosis and treatment performed in an autopsy…”
Get more information

The FOXM1 transcriptional factor promotes the proliferation of leukemia cells through modulation of cell cycle progression in acute myeloid leukemia by Nakamura, Satoki, Hirano, Isao, Okinaka, Keiji, Takemura, Tomonari, Yokota, Daisuke, Ono, Takaaki, Shigeno, Kazuyuki, Shibata, Kiyoshi, Fujisawa, Shinya, Ohnishi, Kazunori

“…FOXM1 is an important cell cycle regulator and regulates cell proliferation. In addition, FOXM1 has been reported to contribute to oncogenesis in various…”
Get full text

A case of chronic myelogenous leukemia responding to imatinib mesilate (Glivec) after relapse of blastic crisis following allogeneic bone marrow transplantation by Fujisawa, Shinya, Yano, Kunio, Kobayashi, Masahide

“…We report a patient with chronic myelogenous leukemia that responded to imatinib mesilate after relapse of blastic crisis following allogeneic bone marrow…”
Get more information

Long-term complete remission following allogeneic PBSCT in a case of relapsed lymphoblastic lymphoma after BMT from the same donor by Fujisawa, Shinya, Yano, Kunio, Kobayashi, Masahide

“…An 18-year-old man was diagnosed as having lymphoblastic lymphoma in January 1997, and treated with chemotherapy. At the 1st relapse, bone marrow…”
Get more information

Spicamycin and KRN5500 Induce Apoptosis in Myeloid and Lymphoid Cell Lines with Down‐regulation of Bcl‐2 Expression and Modulation of Promyelocytic Leukemia Protein by Zhang, Wen Jie, Ohnishi, Kazunori, Yoshida, Hitoshi, Pan, Ling, Maksumova, Lola, Muratkhodjaev, Farkhad, Luo, Jian Min, Shigeno, Kazuyuki, Fujisawa, Shinya, Naito, Kensuke, Nakamura, Satoki, Shinjo, Kaori, Takeshita, Akihiro, Ohno, Ryuzo

“…Spicamycin is a potent inducer of differentiation of human myeloid leukemia cells (HL‐60) and murine myeloid leukemia cells (M1). One of the spicamycin…”
Get full text

Acute myelogenous leukemia with t(6;9)(p23;q34): Report of three patients by Yano, K., Matsui, Hirotaka, Nakano, Yasuyuki, Fujisawa, Shinya, Abe, Miki, Kobayashi, Masahide

“…Acute myelogenous leukemia (AML) with the translocation t(6;9)(p23;q34) is a rare disease entity with a poor prognosis. We report three patients; two were…”
Get full text

JmjC-domain containing histone demethylase 1B-mediated p15(Ink4b) suppression promotes the proliferation of leukemic progenitor cells through modulation of cell cycle progression in acute myeloid leukemia by Nakamura, Satoki, Tan, Lin, Nagata, Yasuyuki, Takemura, Tomonari, Asahina, Aya, Yokota, Daisuke, Yagyu, Tomohiro, Shibata, Kiyoshi, Fujisawa, Shinya, Ohnishi, Kazunori

“…The histone demethylase JHDM1B has been implicated in cell cycle regulation and tumorigenesis. In addition, it has been reported that JHDM1B is highly…”
Get full text