Search Results - "Fujino, Haruka"

Convergent Total Synthesis of Hikizimycin Enabled by Intermolecular Radical Addition to Aldehyde by Fujino, Haruka, Fukuda, Takumi, Nagatomo, Masanori, Inoue, Masayuki

“…Hikizimycin (1), which exhibits powerful anthelmintic activity, has the most densely functionalized structure among nucleoside antibiotics. A central…”
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Total Syntheses of Hikosamine and Hikizimycin by Fujino, Haruka, Nagatomo, Masanori, Inoue, Masayuki

“…Hikizimycin (1) is a potent anthelmintic and antibacterial natural product. The core 4-amino-4-deoxyundecose sugar (hikosamine) of 1 consists of an 11-carbon…”
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A new anti-austerity agent, 4′-O-methylgrynullarin from Derris scandens induces PANC-1 human pancreatic cancer cell death under nutrition starvation via inhibition of Akt/mTOR pathway by Sun, Sijia, Dibwe, Dya Fita, Kim, Min Jo, Omar, Ashraf M., Phan, Nguyen Duy, Fujino, Haruka, Pongterdsak, Nusrin, Chaithatwatthana, Kritsaya, Phrutivorapongkul, Ampai, Awale, Suresh

“…[Display omitted] An ethanolic extract of Derris scandens flowers showed potent preferential cytotoxicity against PANC-1 human pancreatic cancer cells under…”
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Et3Al/Light-Promoted Radical-Polar Crossover Reactions of α‑Alkoxyacyl Tellurides by Yamada, Yutaro, Yoshinaga, Risa, Matsui, Yuki, Nagatomo, Masanori, Fujino, Haruka, Inoue, Masayuki

“…Here, we report new radical-polar crossover reactions of α-alkoxy carbon radicals for constructing highly oxygenated molecules with contiguous stereocenters…”
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Et 3 Al/Light-Promoted Radical-Polar Crossover Reactions of α-Alkoxyacyl Tellurides by Yamada, Yutaro, Yoshinaga, Risa, Matsui, Yuki, Nagatomo, Masanori, Fujino, Haruka, Inoue, Masayuki

“…Here, we report new radical-polar crossover reactions of α-alkoxy carbon radicals for constructing highly oxygenated molecules with contiguous stereocenters…”
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Decarbonylative Radical Coupling of α-Aminoacyl Tellurides: Single-Step Preparation of γ-Amino and α,β-Diamino Acids and Rapid Synthesis of Gabapentin and Manzacidin A by Nagatomo, Masanori, Nishiyama, Hayato, Fujino, Haruka, Inoue, Masayuki

“…A new radical‐based coupling method has been developed for the single‐step generation of various γ‐amino acids and α,β‐diamino acids from α‐aminoacyl…”
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Et3B/Et2AlCl/O2‐Mediated Radical Coupling Reaction between α‐Alkoxyacyl Tellurides and 2‐Hydroxybenzaldehyde Derivatives by Nagatomo, Masanori, Zhang, Keshu, Fujino, Haruka, Inoue, Masayuki

“…A newly devised radical‐based strategy enabled coupling between multiply oxygenated α‐alkoxyacyl tellurides and 2‐hydroxybenzaldehyde derivatives. A reagent…”
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The Total Synthesis of Chalcitrin by Yang, Ming, Yin, Fangjie, Fujino, Haruka, Snyder, Scott A

“…The first total synthesis of the yellow pigment chalcitrin, a structurally distinct pulvinic acid dimer obtained from Chalciporous piperatus, has been achieved…”
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Unified Total Synthesis of Polyoxins J, L, and Fluorinated Analogues on the Basis of Decarbonylative Radical Coupling Reactions by Fujino, Haruka, Nagatomo, Masanori, Paudel, Atmika, Panthee, Suresh, Hamamoto, Hiroshi, Sekimizu, Kazuhisa, Inoue, Masayuki

“…Polyoxins J (1 a) and L (1 b) are important nucleoside antibiotics. The complex and densely functionalized dipeptide structures of 1 a and 1 b contain thymine…”
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Unified Total Synthesis of PolyoxinsJ, L, and Fluorinated Analogues on the Basis of Decarbonylative Radical Coupling Reactions by Fujino, Haruka, Nagatomo, Masanori, Paudel, Atmika, Panthee, Suresh, Hamamoto, Hiroshi, Sekimizu, Kazuhisa, Inoue, Masayuki

“…PolyoxinsJ (1a) and L (1b) are important nucleoside antibiotics. The complex and densely functionalized dipeptide structures of 1a and 1b contain thymine and…”
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Et 3 B/Et 2 AlCl/O 2 ‐Mediated Radical Coupling Reaction between α‐Alkoxyacyl Tellurides and 2‐Hydroxybenzaldehyde Derivatives by Nagatomo, Masanori, Zhang, Keshu, Fujino, Haruka, Inoue, Masayuki

“…A newly devised radical‐based strategy enabled coupling between multiply oxygenated α‐alkoxyacyl tellurides and 2‐hydroxybenzaldehyde derivatives. A reagent…”
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Decarbonylative Radical Coupling of [alpha]-Aminoacyl Tellurides: Single-Step Preparation of [gamma]-Amino and [alpha],[beta]-Diamino Acids and Rapid Synthesis of Gabapentin and ManzacidinA by Nagatomo, Masanori, Nishiyama, Hayato, Fujino, Haruka, Inoue, Masayuki

“…A new radical-based coupling method has been developed for the single-step generation of various [gamma]-amino acids and [alpha],[beta]-diamino acids from…”
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Decarbonylative Radical Coupling of alpha -Aminoacyl Tellurides: Single-Step Preparation of gamma -Amino and alpha , beta -Diamino Acids and Rapid Synthesis of Gabapentin and ManzacidinA by Nagatomo, Masanori, Nishiyama, Hayato, Fujino, Haruka, Inoue, Masayuki

“…A new radical-based coupling method has been developed for the single-step generation of various gamma -amino acids and alpha , beta -diamino acids from alpha…”
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Et3 B/Et2 AlCl/O2 -Mediated Radical Coupling Reaction between α-Alkoxyacyl Tellurides and 2-Hydroxybenzaldehyde Derivatives by Nagatomo, Masanori, Zhang, Keshu, Fujino, Haruka, Inoue, Masayuki

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Unified Total Synthesis of PolyoxinsJ, L, and Fluorinated Analogues on the Basis of Decarbonylative Radical Coupling Reactions by Fujino, Haruka, Nagatomo, Masanori, Paudel, Atmika, Panthee, Suresh, Hamamoto, Hiroshi, Sekimizu, Kazuhisa, Inoue, Masayuki

“…PolyoxinsJ (1a) and L (1b) are important nucleoside antibiotics. The complex and densely functionalized dipeptide structures of 1a and 1b contain thymine and…”
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Unified Total Synthesis of Polyoxins J, L, and Fluorinated Analogues on the Basis of Decarbonylative Radical Coupling Reactions by Fujino, Haruka, Nagatomo, Masanori, Paudel, Atmika, Panthee, Suresh, Hamamoto, Hiroshi, Sekimizu, Kazuhisa, Inoue, Masayuki

“…Polyoxins J (1 a) and L (1 b) are important nucleoside antibiotics. The complex and densely functionalized dipeptide structures of 1 a and 1 b contain thymine…”
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Decarbonylative Radical Coupling of [alpha]-Aminoacyl Tellurides: Single-Step Preparation of [gamma]-Amino and [alpha],[beta]-Diamino Acids and Rapid Synthesis of Gabapentin and ManzacidinA by Nagatomo, Masanori, Nishiyama, Hayato, Fujino, Haruka, Inoue, Masayuki

“…A new radical-based coupling method has been developed for the single-step generation of various [gamma]-amino acids and [alpha],[beta]-diamino acids from…”
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Decarbonylative Radical Coupling of α-Aminoacyl Tellurides: Single-Step Preparation of γ-Amino and α,β-Diamino Acids and Rapid Synthesis of Gabapentin and Manzacidin A by Nagatomo, Masanori, Nishiyama, Hayato, Fujino, Haruka, Inoue, Masayuki

“…A new radical‐based coupling method has been developed for the single‐step generation of various γ‐amino acids and α,β‐diamino acids from α‐aminoacyl…”
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Decarbonylative Radical Coupling of alpha -Aminoacyl Tellurides: Single-Step Preparation of gamma -Amino and alpha , beta -Diamino Acids and Rapid Synthesis of Gabapentin and ManzacidinA by Nagatomo, Masanori, Nishiyama, Hayato, Fujino, Haruka, Inoue, Masayuki

“…A new radical-based coupling method has been developed for the single-step generation of various gamma -amino acids and alpha , beta -diamino acids from alpha…”
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