Search Results - "Fujimoto, N."

First-line nivolumab plus ipilimumab versus chemotherapy in patients with unresectable malignant pleural mesothelioma: 3-year outcomes from CheckMate 743 by Peters, S., Scherpereel, A., Cornelissen, R., Oulkhouir, Y., Greillier, L., Kaplan, M.A., Talbot, T., Monnet, I., Hiret, S., Baas, P., Nowak, A.K., Fujimoto, N., Tsao, A.S., Mansfield, A.S., Popat, S., Zhang, X., Hu, N., Balli, D., Spires, T., Zalcman, G.

“…In the phase III CheckMate 743 study (NCT02899299), first-line nivolumab plus ipilimumab significantly improved overall survival (OS) versus chemotherapy in…”
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Decreased level of interleukin‐10‐producing B cells in patients with pemphigus but not in patients with pemphigoid by Kabuto, M., Fujimoto, N., Takahashi, T., Tanaka, T.

“…Summary Background While the frequency of interleukin (IL)‐10‐producing B (B10) cells is reported to have an inverse correlation with disease activity in some…”
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Successful short desensitization for the eruption of hydroxychloroquine by Hayami, T, Tanaka, T, Fujimoto, N

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Gene polymorphisms in antioxidant enzymes correlate with the efficacy of androgen-deprivation therapy for prostate cancer with implications of oxidative stress by Shiota, M., Fujimoto, N., Itsumi, M., Takeuchi, A., Inokuchi, J., Tatsugami, K., Yokomizo, A., Kajioka, S., Uchiumi, T., Eto, M.

“…Oxidative stress mitigated by antioxidant enzymes is thought to be involved in the progression to castration-resistant prostate cancer (CRPC) during…”
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Feasibility of administering human pancreatic cancer chemotherapy in a spontaneous pancreatic cancer mouse model by Delahoussaye, Abagail M, Abi Jaoude, Joseph, Green, Morgan, Fujimoto, Tara N, Molkentine, Jessica, Garcia Garcia, Carolina J, Gay, Jason P, Feng, Ningping, Marszalek, Joseph, Fowlkes, Natalie, Taniguchi, Cullen M

“…Both modified FOLFIRINOX (mFFX) and gemcitabine/nab-paclitaxel chemotherapy regimens have been shown to improve clinical outcomes in patients with pancreatic…”
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Anti-PD-1 antibody monotherapy versus anti-PD-1 plus anti-CTLA-4 combination therapy as first-line immunotherapy in unresectable or metastatic mucosal melanoma: a retrospective, multicenter study of 329 Japanese cases (JMAC study) by Nakamura, Y., Namikawa, K., Yoshikawa, S., Kiniwa, Y., Maekawa, T., Yamasaki, O., Isei, T., Matsushita, S., Nomura, M., Nakai, Y., Fukushima, S., Saito, S., Takenouchi, T., Tanaka, R., Kato, H., Otsuka, A., Matsuya, T., Baba, N., Nagase, K., Inozume, T., Fujimoto, N., Kuwatsuka, Y., Onishi, M., Kaneko, T., Onuma, T., Umeda, Y., Ogata, D., Takahashi, A., Otsuka, M., Teramoto, Y., Yamazaki, N.

“…Anti-programmed cell death protein 1 (PD-1) antibody monotherapy (PD1) has led to favorable responses in advanced non-acral cutaneous melanoma among Caucasian…”
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Heart failure-inducible gene therapy targeting protein phosphatase 1 prevents progressive left ventricular remodeling by Miyazaki, Yosuke, Ikeda, Yasuhiro, Shiraishi, Kozo, Fujimoto, Shizuka N, Aoyama, Hidekazu, Yoshimura, Koichi, Inui, Makoto, Hoshijima, Masahiko, Kasahara, Hideko, Aoki, Hiroki, Matsuzaki, Masunori

“…The targeting of Ca(2+) cycling has emerged as a potential therapy for the treatment of severe heart failure. These approaches include gene therapy directed at…”
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Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation by Molkentine, Jessica M., Fujimoto, Tara N., Horvath, Thomas D., Grossberg, Aaron J., Garcia, Carolina J. Garcia, Deorukhkar, Amit, de la Cruz Bonilla, Marimar, Lin, Daniel, Samuel, Errol L. G., Chan, Wai Kin, Lorenzi, Philip L., Piwnica-Worms, Helen, Dantzer, Robert, Tour, James M., Mason, Kathryn A., Taniguchi, Cullen M.

“…Unresectable pancreatic cancer is almost universally lethal because chemotherapy and radiation cannot completely stop the growth of the cancer. The major…”
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Polymorphisms of the androgen transporting gene SLCO2B1 may influence the castration resistance of prostate cancer and the racial differences in response to androgen deprivation by Fujimoto, N, Kubo, T, Inatomi, H, Bui, H T T, Shiota, M, Sho, T, Matsumoto, T

“…Background: Organic anion-transporting polypeptides (OATPs) encoded by SLCO mediate the cellular uptake of many compounds, including androgens. SLCO1B3 and…”
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Sézary syndrome involving the intestinal tract by Kokubu, H., Nishikawa, J., Kato, T., Imaeda, H., Kito, K., Andoh, A., Namura, T., Moritani, S., Tanaka, T., Fujimoto, N.

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Deposition of elafin in the involved vascular wall of neutrophil-mediated cutaneous vasculitis by Muto, J., Fujimoto, N., Ono, K., Kobayashi, T., Chen, K.R., Suzuki, S., Wachi, H., Tajima, S.

“…Background Neutrophil elastase plays an important role in skin inflammation induced by neutrophil infiltration. Elafin is an inducible elastase inhibitor…”
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The prognostic impact of serum testosterone during androgen-deprivation therapy in patients with metastatic prostate cancer and the SRD5A2 polymorphism by Shiota, M, Fujimoto, N, Yokomizo, A, Takeuchi, A, Kashiwagi, E, Dejima, T, Kiyoshima, K, Inokuchi, J, Tatsugami, K, Eto, M

“…Background: Although testosterone suppression during androgen-deprivation therapy (ADT) and obesity have been reported to affect ADT efficacy, there are few…”
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Cutaneous macroglobulinosis: successful treatment with rituximab by Oshio‐Yoshii, A., Fujimoto, N., Shiba, Y., Satoh, T.

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The effect of age-related differences in body size and composition on cardiovascular determinants of VO2max by Carrick-Ranson, Graeme, Hastings, Jeffrey L, Bhella, Paul S, Shibata, Shigeki, Fujimoto, Naoki, Palmer, Dean, Boyd, Kara, Levine, Benjamin D

“…A reduction in maximal stroke volume (SVmax) and total blood volume (TBV) has been hypothesized to contribute to the decline in maximal oxygen uptake (VO2max)…”
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Shock, acute disseminated intravascular coagulation, and microvascular thrombosis: is ‘shock liver’ the unrecognized provocateur of ischemic limb necrosis: comment by Wada, H., Matsumoto, T., Fujimoto, N., Imai, H., Suzuki, K., Katayama, N.

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Familial Mediterranean fever with onset in the 70s showing various neutrophilic dermatosis by Takahashi, T., Fujimoto, N., Yamaguchi, A., Hayashi, H., Migita, K., Ida, H., Tanaka, T.

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Serum intact parathyroid hormone levels predict hospitalisation for heart failure by Sugimoto, T, Tanigawa, T, Onishi, K, Fujimoto, N, Matsuda, A, Nakamori, S, Matsuoka, K, Nakamura, T, Koji, T, Ito, M

“…To assess whether circulating levels of intact parathyroid hormone (intact PTH) in outpatients predict hospitalisation for heart failure (HF). Eighty-eight…”
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Primary cutaneous follicle center lymphoma in a patient with WHIM syndrome by Yoshii, Y., Kato, T., Ono, K., Takahashi, E., Fujimoto, N., Kobayashi, S., Kimura, F., Nonoyama, S., Satoh, T.

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Cardiovascular response to exercise training in the systemic right ventricle of adults with transposition of the great arteries by Shafer, K. M., Janssen, L., Carrick‐Ranson, G., Rahmani, S., Palmer, D., Fujimoto, N., Livingston, S., Matulevicius, S. A., Forbess, L. W., Brickner, B., Levine, B. D.

“…Key Points Patients with transposition of the great arteries (TGA) and systemic right ventricles have premature congestive heart failure; there is also a…”
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Monitoring of hemostatic abnormalities in major orthopedic surgery patients treated with edoxaban by APTT waveform by Hasegawa, M., Wada, H., Tone, S., Yamaguchi, T., Wakabayashi, H., Ikejiri, M., Watanabe, M., Fujimoto, N., Matsumoto, T., Ohishi, K., Yamashita, Y., Katayama, N., Sudo, A.

“…Introduction An analysis of the activated partial thromboplastin time (APTT) in major orthopedic surgery patients receiving edoxaban for the prevention of…”
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