Search Results - "Fujii, Yoshihiro"

Hyperthermia inhibits homologous recombination repair and sensitizes cells to ionizing radiation in a time- and temperature-dependent manner by Genet, Stefan C., Fujii, Yoshihiro, Maeda, Junko, Kaneko, Masami, Genet, Matthew D., Miyagawa, Kiyoshi, Kato, Takamitsu A.

“…Hyperthermia has long been known as a radio‐sensitizing agent that displays anti‐tumor effects, and has been developed as a therapeutic application. The…”
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Effect of Asian dust on pulmonary function in adult asthma patients in western Japan: A panel study by Watanabe, Masanari, Noma, Hisashi, Kurai, Jun, Sano, Hiroyuki, Mikami, Masaaki, Yamamoto, Hiroyuki, Ueda, Yasuto, Touge, Hirokazu, Fujii, Yoshihiro, Ikeda, Toshikazu, Tokuyasu, Hirokazu, Konishi, Tatsuya, Yamasaki, Akira, Igishi, Tadashi, Shimizu, Eiji

“…Asian dust (AD) has become a major health concern. The concentration of AD is typically expressed in particulate matter less than 10 μm (PM10) and 2.5 μm…”
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Tensile mechanical analysis of anisotropy and velocity dependence of the spinal cord white matter: a biomechanical study by Nishida, Norihiro, Sakuramoto, Itsuo, Fujii, Yoshihiro, Hutama, Rudolf, Jiang, Fei, Ohgi, Junji, Imajo, Yasuaki, Suzuki, Hidenori, Funaba, Masahiro, Chen, Xian, Sakai, Takashi

“…In spinal cord injuries, external forces from various directions occur at various velocities. Therefore, it is important to physically evaluate whether the…”
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Radiosensitization of human lung cancer cells by the novel purine-scaffold Hsp90 inhibitor, PU-H71 by SEGAWA, TATSUYA, FUJII, YOSHIHIRO, TANAKA, AYA, BANDO, SHIN-ICHI, OKAYASU, RYUICHI, OHNISHI, KEN, KUBOTA, NOBUO

“…The molecular chaperone heat shock protein 90 (Hsp90) is involved in the maturation and stabilization of a wide range of oncogenic client proteins for…”
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Solution Radioactivated by Hadron Radiation Can Increase Sister Chromatid Exchanges by Maeda, Junko, Yurkon, Charles R, Fujii, Yoshihiro, Fujisawa, Hiroshi, Kato, Sayaka, Brents, Colleen A, Uesaka, Mitsuru, Fujimori, Akira, Kitamura, Hisashi, Kato, Takamitsu A

“…When energetic particles irradiate matter, it becomes activated by nuclear reactions. Radioactivation induced cellular effects are not clearly understood, but…”
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Potentially Lethal Damage Repair in Drug Arrested G2-Phase Cells after Radiation Exposure by Maeda, Junko, Bell, Justin J., Genet, Stefan C., Fujii, Yoshihiro, Genet, Matthew D., Brents, Colleen A., Genik, Paula C., Kato, Takamitsu A.

“…Potentially lethal damage (PLD) repair has been defined as that property conferring the ability of cells to recover from DNA damage depending on the…”
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Plastic induction of CD133AC133-positive cells in the microenvironment of glioblastoma spheroids by OHNISHI, KEN, TANI, TOSHIAKI, BANDO, SHIN-ICHI, KUBOTA, NOBUO, FUJII, YOSHIHIRO, HATANO, OSAMU, HARADA, HIROSI

“…Recent studies showed that the stemness of cancer stem cells is maintained under a hypoxic microenvironment. However, the relationship of the hypoxic…”
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Comparative Study of Radioresistance between Feline Cells and Human Cells by Fujii, Yoshihiro, Yurkon, Charles R., Maeda, Junko, Genet, Stefan C., Kubota, Nobuo, Fujimori, Akira, Mori, Takashi, Maruo, Kohji, Kato, Takamitsu A.

“…Radioresistance of cats has been seen in animal radiotherapy. Feline radioresistance and its underlying mechanism(s) were investigated in fibroblast cells and…”
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Hyperthermia-induced radiosensitization in CHO wild-type, NHEJ repair mutant and HR repair mutant following proton and carbon-ion exposure by MAEDA, JUNKO, FUJII, YOSHIHIRO, FUJISAWA, HIROSHI, HIRAKAWA, HIROKAZU, CARTWRIGHT, IAN M, UESAKA, MITSURU, KITAMURA, HISASHI, FUJIMORI, AKIRA, KATO, TAKAMITSU A

“…The DNA repair mechanisms involved in hyperthermia-induced radiosensitization with proton and carbon ion radiation exposure were investigated in the present…”
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Comparison of the bromodeoxyuridine-mediated sensitization effects between low-LET and high-LET ionizing radiation on DNA double-strand breaks by FUJII, YOSHIHIRO, GENET, MATTHEW D, ROYBAL, ERICA J, KUBOTA, NOBUO, OKAYASU, RYUICHI, MIYAGAWA, KIYOSHI, FUJIMORI, AKIRA, KATO, TAKAMITSU A

“…The incorporation of halogenated pyrmidines such as bromo- and iodo-deoxyuridines (BrdU, IdU) into DNA as thymidine analogs enhances cellular radiosensitivity…”
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DNA Damage Focus Formation Assay by Fujii, Yoshihiro

“…Advanced techniques allow investigating cellular DNA damage measurements. Ionizing radiation produces multiple DNA damages. Among them, DNA double strand…”
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Comparison of cellular lethality in DNA repair-proficient or -deficient cell lines resulting from exposure to 70 MeV/n protons or 290 MeV/n carbon ions by GENET, STEFAN C, MAEDA, JUNKO, FUJISAWA, HIROSHI, YURKON, CHARLES R, FUJII, YOSHIHIRO, ROMERO, ASHLEY M, GENIK, PAULA C, FUJIMORI, AKIRA, KITAMURA, HISASHI, KATO, TAKAMITSU A

“…Charged particle therapy utilizing protons or carbon ions has been rapidly intensifying over recent years. The present study was designed to jointly…”
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A Novel PET Imaging Using 64Cu-Labeled Monoclonal Antibody against Mesothelin Commonly Expressed on Cancer Cells by Matsuura, Eiji, Kumon, Hiromi, Kita, Shoichi, Kishi, Yoshiro, Fujii, Yoshihiro, Yakushiji, Hiromasa, Takenaka, Fumiaki, Sasaki, Takanori, Kobayashi, Kazuko, Shen, Lianhua

“…Mesothelin (MSLN) is a 40-kDa cell differentiation-associated glycoprotein appearing with carcinogenesis and is highly expressed in many human cancers,…”
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Effects of targeted phosphorylation site mutations in the DNA-PKcs phosphorylation domain on low and high LET radiation sensitivity by CARTWRIGHT, IAN M, BELL, JUSTIN J, MAEDA, JUNKO, GENET, MATTHEW D, ROMERO, ASHLEY, FUJII, YOSHIHIRO, FUJIMORI, AKIRA, KITAMUTA, HISASHI, KAMADA, TADASHI, CHEN, DAVID J, KATO, TAKAMITSU A

“…The present study investigated the effect of targeted mutations in the DNA-dependent protein kinase catalytic subunit and phosphorylation domains on the…”
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Ascorbic acid gives different protective effects in human cells exposed to X-rays and heavy ions by Fujii, Yoshihiro, Kato, Takamitsu A., Ueno, Akiko, Kubota, Nobuo, Fujimori, Akira, Okayasu, Ryuichi

“…We studied the effects and mechanisms of ascorbic acid as a radiation protector. Cell survival, repair of DNA double strand breaks (DSBs), and sister chromatid…”
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A screening test for capsaicin-stimulated salivary flow using filter paper: a study for diagnosis of hyposalivation with a complaint of dry mouth by Kanehira, Takashi, DDS, PhD, Yamaguchi, Tomotaka, DDS, Asano, Kozo, PhD, Morita, Manabu, DDS, PhD, Maeshima, Etsuko, MD, PhD, Matsuda, Akemi, DDS, PhD, Fujii, Yoshihiro, MD, Sakamoto, Wataru, MD

“…Objective The purpose of this study was to develop a simple screening technique for diagnosis of hyposalivation with dry mouth by estimation of…”
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Trichostatin A, a histone deacetylase inhibitor, down-regulates interleukin-12 transcription in SV-40-transformed lung epithelial cells by Iwata, Kyoko, Tomita, Katsuyuki, Sano, Hiroyuki, Fujii, Yoshihiro, Yamasaki, Akira, Shimizu, Eiji

“…Inhibition of histone deacetylation results in increased gene expression. Trichostatin (Ts)A, a specific histone deacetylase (HDAC) inhibitor, up-regulates…”
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Effects of lipofectin–antigen complexes on major histocompatibility complex class I-restricted antigen presentation pathway in murine dendritic cells and on dendritic cell maturation by Okada, Naoki, Saito, Tomomi, Mori, Kohei, Masunaga, Yasushige, Fujii, Yoshihiro, Fujita, Junko, Fujimoto, Kyoko, Nakanishi, Tsuyoshi, Tanaka, Keiichi, Nakagawa, Shinsaku, Mayumi, Tadanori, Fujita, Takuya, Yamamoto, Akira

“…We previously reported that exogenous antigens complexed with the cationic liposome lipofectin (LF) were efficiently presented via major histocompatibility…”
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Synaptonemal complex protein SYCP3 impairs mitotic recombination by interfering with BRCA2 by Hosoya, Noriko, Okajima, Miyuki, Kinomura, Aiko, Fujii, Yoshihiro, Hiyama, Takashi, Sun, Jiying, Tashiro, Satoshi, Miyagawa, Kiyoshi

“…The meiosis‐specific synaptonemal complex protein SYCP3 has been reported to be aberrantly expressed in tumours. However, in contrast to its well‐defined…”
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Serum HE4 as a diagnostic and prognostic marker for lung cancer by Iwahori, Kota, Suzuki, Hidekazu, Kishi, Yoshiro, Fujii, Yoshihiro, Uehara, Rie, Okamoto, Norio, Kobayashi, Masashi, Hirashima, Tomonori, Kawase, Ichiro, Naka, Tetsuji

“…We evaluated the diagnostic and prognostic efficacy of human epididymis protein 4 (HE4) for lung cancer patients by using our novel enzyme-linked immunosorbent…”
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