Search Results - "Fuglerud, Bettina M."

Cell diversity and plasticity during atrioventricular heart valve EMTs by Lotto, Jeremy, Cullum, Rebecca, Drissler, Sibyl, Arostegui, Martin, Garside, Victoria C., Fuglerud, Bettina M., Clement-Ranney, Makenna, Thakur, Avinash, Underhill, T. Michael, Hoodless, Pamela A.

“…Epithelial-to-mesenchymal transitions (EMTs) of both endocardium and epicardium guide atrioventricular heart valve formation, but the cellular complexity and…”
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Chromatin occupancy and target genes of the haematopoietic master transcription factor MYB by Lemma, Roza B., Ledsaak, Marit, Fuglerud, Bettina M., Sandve, Geir Kjetil, Eskeland, Ragnhild, Gabrielsen, Odd S.

“…The transcription factor MYB is a master regulator in haematopoietic progenitor cells and a pioneer factor affecting differentiation and proliferation of these…”
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The pioneer factor activity of c-Myb involves recruitment of p300 and induction of histone acetylation followed by acetylation-induced chromatin dissociation by Fuglerud, Bettina M, Ledsaak, Marit, Rogne, Marie, Eskeland, Ragnhild, Gabrielsen, Odd S

“…The concept of pioneer transcription factors is emerging as an essential part of the epigenetic regulation, taking place during cell development and…”
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HNF4A guides the MLL4 complex to establish and maintain H3K4me1 at gene regulatory elements by Thakur, Avinash, Park, Kwangjin, Cullum, Rebecca, Fuglerud, Bettina M., Khoshnoodi, Mina, Drissler, Sibyl, Stephan, Tabea L., Lotto, Jeremy, Kim, Donghwan, Gonzalez, Frank J., Hoodless, Pamela A.

“…Hepatocyte nuclear factor 4A (HNF4A/NR2a1), a transcriptional regulator of hepatocyte identity, controls genes that are crucial for liver functions, primarily…”
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SOX9 reprograms endothelial cells by altering the chromatin landscape by Fuglerud, Bettina M, Drissler, Sibyl, Lotto, Jeremy, Stephan, Tabea L, Thakur, Avinash, Cullum, Rebecca, Hoodless, Pamela A

“…Abstract The transcription factor SOX9 is activated at the onset of endothelial-to-mesenchymal transition (EndMT) during embryonic development and in…”
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Hepatocyte Nuclear Factor 4‐Alpha Is Essential for the Active Epigenetic State at Enhancers in Mouse Liver by Thakur, Avinash, Wong, Jasper C.H., Wang, Evan Y., Lotto, Jeremy, Kim, Donghwan, Cheng, Jung‐Chien, Mingay, Matthew, Cullum, Rebecca, Moudgil, Vaishali, Ahmed, Nafeel, Tsai, Shu‐Huei, Wei, Wei, Walsh, Colum P., Stephan, Tabea, Bilenky, Misha, Fuglerud, Bettina M., Karimi, Mohammad M., Gonzalez, Frank J., Hirst, Martin, Hoodless, Pamela A.

“…Cell‐fate determination is influenced by interactions between master transcription factors (TFs) and cis‐regulatory elements. Hepatocyte nuclear factor 4 alpha…”
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A c-Myb mutant causes deregulated differentiation due to impaired histone binding and abrogated pioneer factor function by Fuglerud, Bettina M, Lemma, Roza B, Wanichawan, Pimthanya, Sundaram, Arvind Y M, Eskeland, Ragnhild, Gabrielsen, Odd S

“…The transcription factor c-Myb is involved in early differentiation and proliferation of haematopoietic cells, where it operates as a regulator of self-renewal…”
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HNF4A is essential for the active epigenetic state at enhancers in mouse liver by Thakur, Avinash, Wong, Jasper C. H., Wang, Evan Y., Lotto, Jeremy, Kim, Donghwan, Cheng, Jung-Chien, Mingay, Matthew, Cullum, Rebecca, Moudgil, Vaishali, Ahmed, Nafeel, Tsai, Shu-Huei, Wei, Wei, Walsh, Colum P., Stephan, Tabea, Bilenky, Misha, Fuglerud, Bettina M., Karimi, Mohammad M., Gonzalez, Frank J., Hirst, Martin, Hoodless, Pamela A.

“…Cell fate determination is influenced by interactions between master transcription factors (TFs) and cis-regulatory elements. Hepatocyte nuclear factor 4 alpha…”
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