Search Results - "Fuerst, Sophie"
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Regulatory T Cells with Additional COX-2 Expression Are Independent Negative Prognosticators for Vulvar Cancer Patients
Published in International journal of molecular sciences (22-04-2022)“…Vulvar cancer incidence numbers have been steadily rising over the past decades. In particular, the number of young patients with vulvar cancer has recently…”
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LDOC1 as Negative Prognostic Marker for Vulvar Cancer Patients
Published in International journal of molecular sciences (05-12-2020)“…So far, studies about targeted therapies and predictive biomarkers for vulva carcinomas are rare. The leucine zipper downregulated in cancer 1 gene (LDOC1) has…”
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Combined COX-2/PPARγ Expression as Independent Negative Prognosticator for Vulvar Cancer Patients
Published in Diagnostics (Basel) (10-03-2021)“…Vulvar cancer incidence numbers have been rising steadily over the past decades. Especially the number of young patients with vulvar cancer increased recently…”
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Adjuvant therapy in lymph node-positive vulvar cancer: the AGO-CaRE-1 study
Published in JNCI : Journal of the National Cancer Institute (01-03-2015)“…Women with node-positive vulvar cancer have a high risk for disease recurrence. Indication criteria for adjuvant radiotherapy are controversial. This study was…”
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MTA1 as negative prognostic marker in vulvar carcinoma
Published in Journal of cancer research and clinical oncology (01-08-2023)“…Purpose Vulvar cancer is the fourth most common malignancy of the female genital tract after endometrial, ovarian, and cervical carcinoma and affects mainly…”
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p53 and p16 expression profiles in vulvar cancer: a translational analysis by the Arbeitsgemeinschaft Gynäkologische Onkologie Chemo and Radiotherapy in Epithelial Vulvar Cancer study group
Published in American journal of obstetrics and gynecology (01-06-2021)“…There are 2 known pathways for tumorigenesis of vulvar squamous cell carcinoma—a human papillomavirus–dependent pathway characterized by p16 overexpression and…”
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Prostaglandin E2 receptor EP1 expression in vulvar cancer
Published in Journal of cancer research and clinical oncology (01-07-2023)“…Purpose In recent years, incidence of vulvar cancer has been on the rise, whereas therapeutic options are still restricted. Therefore, new prognosticators and…”
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Human epididymis protein 4 (HE4) in benign and malignant diseases
Published in Clinical chemistry and laboratory medicine (01-12-2012)“…Human epididymis protein 4 (HE4) is described as a useful new biomarker in ovarian cancer. As HE4 is neither tumor nor organ specific, we intensively…”
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Adjuvant radiotherapy and local recurrence in vulvar cancer – a subset analysis of the AGO-CaRE-1 study
Published in Gynecologic oncology (01-01-2022)“…The impact of adjuvant radiotherapy (RT) to the vulva with regard to prognosis and local recurrence in patients with vulvar squamous cell cancer (VSCC) is…”
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Role of tumour-free margin distance for loco-regional control in vulvar cancer—a subset analysis of the Arbeitsgemeinschaft Gynäkologische Onkologie CaRE-1 multicenter study
Published in European journal of cancer (1990) (01-12-2016)“…Abstract Aim of the study A tumour-free pathological resection margin of ≥8 mm is considered state-of-the-art. Available evidence is based on heterogeneous…”
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Predicting the course of disease in recurrent vulvar cancer – A subset analysis of the AGO-CaRE-1 study
Published in Gynecologic oncology (01-09-2019)“…AbstractObjectiveIn vulvar cancer (VSCC), the course of disease with regard to localization of recurrence and relation of different recurrence sites is poorly…”
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Immune phenotypes and T-cell density at the invasive margin correlate with prognosis in epithelial vulvar cancer
Published in Journal of clinical oncology (01-06-2022)“…5599 Background: Tumor infiltrating lymphocytes (TILs) in the cancer microenvironment are of prognostic value in many solid tumors. However, only little is…”
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Age, treatment and prognosis of patients with squamous cell vulvar cancer (VSCC) - analysis of the AGO-CaRE-1 study
Published in Gynecologic oncology (01-05-2021)“…Despite an increasing incidence with simultaneous decreasing age of onset, vulvar squamous cell carcinoma (VSCC) is still a disease that mainly effects the…”
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Lymph node ratio in inguinal lymphadenectomy for squamous cell vulvar cancer: Results from the AGO-CaRE-1 study
Published in Gynecologic oncology (01-05-2019)“…Lymph node ratio (LNR) can predict treatment outcome and prognosis in patients with solid tumors. Aim of the present analysis was to confirm the concept of…”
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Predictive factors for lymph node metastases in vulvar cancer. An analysis of the AGO-CaRE-1 multicenter study
Published in Gynecologic oncology (01-09-2019)“…AbstractBackgroundLymph node (LN) metastasis is the most important prognostic factor in primary vulvar cancer. Assessing risk factors for the incidence and…”
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Cytoplasmic VDR expression as an independent risk factor for ovarian cancer
Published in Histochemistry and cell biology (01-10-2020)“…The vitamin D receptor (VDR), primarily known as a crucial mediator of calcium homeostasis and metabolism, has been shown to play a significant role in various…”
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Role of Pelvic Lymph Node Resection in Vulvar Squamous Cell Cancer: A Subset Analysis of the AGO-CaRE-1 Study
Published in Annals of surgical oncology (01-10-2021)“…Background As the population at risk for pelvic nodal involvement remains poorly described, the role of pelvic lymphadenectomy (LAE) in vulvar squamous cell…”
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Outcome After Sentinel Lymph Node Dissection in Vulvar Cancer: A Subgroup Analysis of the AGO-CaRE-1 Study
Published in Annals of surgical oncology (01-05-2017)“…Purpose Analyzing the large patient cohort of the multicenter AGO-CaRE-1 study, we compared isolated sentinel lymph node dissection (SLND) with radical lymph…”
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Evaluation of treatment patterns and prognosis in correlation with age in patients with vulvar cancer: A subset analysis of the AGO-CaRE-1 study
Published in Journal of clinical oncology (20-05-2020)“…Abstract only 6090 Background: Despite an increasing incidence with simultaneous decreasing age of onset, the impact of age on prognosis and treatment patterns…”
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Peri-operative oral immunonutrition in malnourished ovarian cancer patients assessed by the nutritional risk screening
Published in Archives of gynecology and obstetrics (01-06-2018)“…Objectives Aim of this study was to determine whether peri-operative immunonutrition can decrease complications and the length of stay (LOS) in malnourished…”
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