Search Results - "Fuentes, Daniel R."
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Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation
Published in eLife (02-08-2018)“…Recent work suggests extensive adaptation of transposable elements (TEs) for host gene regulation. However, high numbers of integrations typical of TEs,…”
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Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
Published in Cell (24-10-2013)“…Direct lineage reprogramming is a promising approach for human disease modeling and regenerative medicine, with poorly understood mechanisms. Here, we reveal a…”
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Induction of human neuronal cells by defined transcription factors
Published in Nature (London) (11-08-2011)“…Neurons from fibroblasts Three papers in this issue demonstrate the production of functional induced neuronal (iN) cells from human fibroblasts, a procedure…”
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Inappropriate p53 activation during development induces features of CHARGE syndrome
Published in Nature (London) (09-10-2014)“…Inappropriate activation of the tumour-suppressor protein p53 during development can promote phenotypes similar to those of CHARGE syndrome, suggesting that…”
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Author Correction: Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates
Published in Nature (London) (20-06-2024)Get full text
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Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates
Published in Nature (London) (13-04-2017)“…The neuron-specific transcription factor Myt1l represses many somatic lineage programs, but not the neuronal lineage program, to both induce and maintain…”
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Hierarchical mechanisms for transcription factor-mediated reprogramming of fibroblasts to neurons
Published in Cell (24-10-2013)“…Direct lineage reprogramming is a promising approach for human disease modeling and regenerative medicine with poorly understood mechanisms. Here we reveal a…”
Get full text
Journal Article