Search Results - "Fudi Wang"

The multifaceted role of ferroptosis in liver disease by Chen, Junyi, Li, Xiaopeng, Ge, Chaodong, Min, Junxia, Wang, Fudi

“…Ferroptosis is an iron-dependent form of non-apoptotic cell death characterized by excessive lipid peroxidation and associated with a plethora of pathological…”
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Copper homeostasis and cuproptosis in health and disease by Chen, Liyun, Min, Junxia, Wang, Fudi

“…As an essential micronutrient, copper is required for a wide range of physiological processes in virtually all cell types. Because the accumulation of…”
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Ion sieving by a two-dimensional Ti3C2T x alginate lamellar membrane with stable interlayer spacing by Jin Wang, Zhijie Zhang, Jiani Zhu, Mengtao Tian, Shuchang Zheng, Fudi Wang, Xudong Wang, Lei Wang

“…Two dimensional lamellar membranes are attractive for anomalous water and ion transfer, but performance is hindered by swelling. Here, the authors stabilize a…”
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Fighting the SARS-CoV-2 Pandemic: Focusing a New Lens on COVID-19 by Wang, Fudi

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Targeting ferroptosis opens new avenues for the development of novel therapeutics by Sun, Shumin, Shen, Jie, Jiang, Jianwei, Wang, Fudi, Min, Junxia

“…Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics, including altered iron homeostasis, reduced defense against…”
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Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis by Fang, Xuexian, Cai, Zhaoxian, Wang, Hao, Han, Dan, Cheng, Qi, Zhang, Pan, Gao, Feng, Yu, Yingying, Song, Zijun, Wu, Qian, An, Peng, Huang, Sicong, Pan, Jianwei, Chen, Hou-Zao, Chen, Jinghai, Linkermann, Andreas, Min, Junxia, Wang, Fudi

“…RATIONALE:Maintaining iron homeostasis is essential for proper cardiac function. Both iron deficiency and iron overload are associated with cardiomyopathy and…”
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Characterization of ferroptosis in murine models of hemochromatosis by Wang, Hao, An, Peng, Xie, Enjun, Wu, Qian, Fang, Xuexian, Gao, Hong, Zhang, Zhuzhen, Li, Yuzhu, Wang, Xudong, Zhang, Jiaying, Li, Guoli, Yang, Lei, Liu, Wei, Min, Junxia, Wang, Fudi

“…Ferroptosis is a recently identified iron‐dependent form of nonapoptotic cell death implicated in brain, kidney, and heart pathology. However, the biological…”
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Hepatic transferrin plays a role in systemic iron homeostasis and liver ferroptosis by Yu, Yingying, Jiang, Li, Wang, Hao, Shen, Zhe, Cheng, Qi, Zhang, Pan, Wang, Jiaming, Wu, Qian, Fang, Xuexian, Duan, Lingyan, Wang, Shufen, Wang, Kai, An, Peng, Shao, Tuo, Chung, Raymond T., Zheng, Shusen, Min, Junxia, Wang, Fudi

“…Although the serum-abundant metal-binding protein transferrin (encoded by the Trf gene) is synthesized primarily in the liver, its function in the liver is…”
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Genetic Support of A Causal Relationship Between Iron Status and Type 2 Diabetes: A Mendelian Randomization Study by Wang, Xinhui, Fang, Xuexian, Zheng, Wanru, Zhou, Jiahui, Song, Zijun, Xu, Mingqing, Min, Junxia, Wang, Fudi

“…Iron overload is a known risk factor for type 2 diabetes (T2D); however, iron overload and iron deficiency have both been associated with metabolic disorders…”
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Comorbid Chronic Diseases and Acute Organ Injuries Are Strongly Correlated with Disease Severity and Mortality among COVID-19 Patients: A Systemic Review and Meta-Analysis by Wang, Xinhui, Fang, Xuexian, Cai, Zhaoxian, Wu, Xiaotian, Gao, Xiaotong, Min, Junxia, Wang, Fudi

“…The recent outbreak of COVID-19 has been rapidly spreading on a global scale. To date, there is no specific vaccine against the causative virus, SARS-CoV-2,…”
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Ferroptosis as a target for protection against cardiomyopathy by Fang, Xuexian, Wang, Hao, Han, Dan, Xie, Enjun, Yang, Xiang, Wei, Jiayu, Gu, Shanshan, Gao, Feng, Zhu, Nali, Yin, Xiangju, Cheng, Qi, Zhang, Pan, Dai, Wei, Chen, Jinghai, Yang, Fuquan, Yang, Huang-Tian, Linkermann, Andreas, Gu, Wei, Min, Junxia, Wang, Fudi

“…Heart disease is the leading cause of death worldwide. A key pathogenic factor in the development of lethal heart failure is loss of terminally differentiated…”
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The Role of Zinc and Zinc Homeostasis in Macrophage Function by Min, Junxia, Zhao, Lu, Dai, Wei, Gao, Hong, Wang, Fudi

“…Zinc has long been recognized as an essential trace element, playing roles in the growth and development of all living organisms. In recent decades, zinc…”
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DHODH tangoing with GPX4 on the ferroptotic stage by Wang, Fudi, Min, Junxia

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Antioxidants Mediate Both Iron Homeostasis and Oxidative Stress by Imam, Mustapha Umar, Zhang, Shenshen, Ma, Jifei, Wang, Hao, Wang, Fudi

“…Oxidative stress is a common denominator in the pathogenesis of many chronic diseases. Therefore, antioxidants are often used to protect cells and tissues and…”
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Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease by Bao, Wen-Dai, Pang, Pei, Zhou, Xiao-Ting, Hu, Fan, Xiong, Wan, Chen, Kai, Wang, Jing, Wang, Fudi, Xie, Dong, Hu, Ya-Zhuo, Han, Zhi-Tao, Zhang, Hong-Hong, Wang, Wang-Xia, Nelson, Peter T., Chen, Jian-Guo, Lu, Youming, Man, Heng-Ye, Liu, Dan, Zhu, Ling-Qiang

“…Iron homeostasis disturbance has been implicated in Alzheimer’s disease (AD), and excess iron exacerbates oxidative damage and cognitive defects. Ferroptosis…”
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Causal Associations of Circulating Lipids with Osteoarthritis: A Bidirectional Mendelian Randomization Study by Meng, Hongen, Jiang, Li, Song, Zijun, Wang, Fudi

“…Osteoarthritis (OA) imposes an increasing social burden due to global activity limitations, especially among the aged. Links between circulating lipids and OA…”
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GPX4 and vitamin E cooperatively protect hematopoietic stem and progenitor cells from lipid peroxidation and ferroptosis by Hu, Qian, Zhang, Yifan, Lou, Huiling, Ou, Zexian, Liu, Jin, Duan, Wentao, Wang, Hao, Ge, Yuanlong, Min, Junxia, Wang, Fudi, Ju, Zhenyu

“…Ferroptosis, a newly defined mode of regulated cell death caused by unbalanced lipid redox metabolism, is implicated in various tissue injuries and…”
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Deletion of ferritin H in neurons counteracts the protective effect of melatonin against traumatic brain injury‐induced ferroptosis by Rui, Tongyu, Wang, Haochen, Li, Qianqian, Cheng, Ying, Gao, Yuan, Fang, Xuexian, Ma, Xuying, Chen, Guang, Gao, Cheng, Gu, Zhiya, Song, Shunchen, Zhang, Jian, Wang, Chunling, Wang, Zufeng, Wang, Tao, Zhang, Mingyang, Min, Junxia, Chen, Xiping, Tao, Luyang, Wang, Fudi, Luo, Chengliang

“…Accumulating evidence demonstrates that ferroptosis may be important in the pathophysiological process of traumatic brain injury (TBI). As a major hormone of…”
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VPS34 Acetylation Controls Its Lipid Kinase Activity and the Initiation of Canonical and Non-canonical Autophagy by Su, Hua, Yang, Fei, Wang, Qiuting, Shen, Qiuhong, Huang, Jingtao, Peng, Chao, Zhang, Yi, Wan, Wei, Wong, Catherine C.L., Sun, Qiming, Wang, Fudi, Zhou, Tianhua, Liu, Wei

“…The class III phosphoinositide 3-kinase VPS34 plays a key role in the regulation of vesicular trafficking and macroautophagy. So far, we know little about the…”
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Dietary magnesium intake and the risk of cardiovascular disease, type 2 diabetes, and all-cause mortality: a dose-response meta-analysis of prospective cohort studies by Fang, Xuexian, Wang, Kai, Han, Dan, He, Xuyan, Wei, Jiayu, Zhao, Lu, Imam, Mustapha Umar, Ping, Zhiguang, Li, Yusheng, Xu, Yuming, Min, Junxia, Wang, Fudi

“…Although studies have examined the association between dietary magnesium intake and health outcome, the results are inconclusive. Here, we conducted a…”
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