Search Results - "Fuchs, Yannick F."

Gene Expression-Based Identification of Antigen-Responsive CD8 + T Cells on a Single-Cell Level by Fuchs, Yannick F, Sharma, Virag, Eugster, Anne, Kraus, Gloria, Morgenstern, Robert, Dahl, Andreas, Reinhardt, Susanne, Petzold, Andreas, Lindner, Annett, Löbel, Doreen, Bonifacio, Ezio

“…CD8 T cells are important effectors of adaptive immunity against pathogens, tumors, and self antigens. Here, we asked how human cognate antigen-responsive CD8…”
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A Golgi PKD Activity Reporter Reveals a Crucial Role of PKD in Nocodazole‐Induced Golgi Dispersal by Fuchs, Yannick F., Eisler, Stephan A., Link, Gisela, Schlicker, Oliver, Bunt, Gertrude, Pfizenmaier, Klaus, Hausser, Angelika

“…The protein kinase D (PKD) family comprises multifunctional serine/threonine‐specific protein kinases with three mammalian isoforms: PKD1, PKD2 and PKD3. A…”
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CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage by Fuchs, Yannick F., Eugster, Anne, Dietz, Sevina, Sebelefsky, Christian, Kühn, Denise, Wilhelm, Carmen, Lindner, Annett, Gavrisan, Anita, Knoop, Jan, Dahl, Andreas, Ziegler, Anette-G., Bonifacio, Ezio

“…CD8 + T cells directed against beta cell autoantigens are considered relevant for the pathogenesis of type 1 diabetes. Using single cell T cell receptor…”
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Next Generation Biobanking: Employing a Robotic System for Automated Mononuclear Cell Isolation by Fuchs, Yannick F, Brunner, Jonathan, Weigelt, Marc, Schieferdecker, Anja, Morgenstern, Robert, Sturm, Andrea, Winter, Boris, Jambor, Helena, Stölzel, Friedrich, Ruhnke, Leo, von Bonin, Malte, Rücker-Braun, Elke, Heidenreich, Falk, Fuchs, Anke, Bonifacio, Ezio, Bornhäuser, Martin, Poitz, David M, Altmann, Heidi

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Vagaries of the ELISpot assay: Specific detection of antigen responsive cells requires purified CD8+ T cells and MHC class I expressing antigen presenting cell lines by Fuchs, Yannick F, Jainta, Gregor W, Kühn, Denise, Wilhelm, Carmen, Weigelt, Marc, Karasinsky, Anne, Upadhyaya, Bhaskar, Ziegler, Anette-G, Bonifacio, Ezio

“…Abstract Quantification of antigen-specific CD8+ T cells is important for monitoring infection, vaccination, and response to therapy in cancer and…”
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Protein kinase D controls the integrity of Golgi apparatus and the maintenance of dendritic arborization in hippocampal neurons by Czöndör, Katalin, Ellwanger, Kornelia, Fuchs, Yannick F, Lutz, Sylke, Gulyás, Márton, Mansuy, Isabelle M, Hausser, Angelika, Pfizenmaier, Klaus, Schlett, Katalin

“…Protein kinase D (PKD) is known to participate in various cellular functions, including secretory vesicle fission from the Golgi and plasma membrane-directed…”
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G-PKDrep-live, a genetically encoded FRET reporter to measure PKD activity at the trans-Golgi-network by Eisler, Stephan A., Fuchs, Yannick F., Pfizenmaier, Klaus, Hausser, Angelika

“…The serine/threonine protein kinase D (PKD) is recruited to the trans‐Golgi‐network (TGN) by interaction with diacylglycerol (DAG) and Arf1 and promotes the…”
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Beta-cell autoimmunity by Fuchs, Yannick F, Adler, Kerstin, Bonifacio, Ezio

“…Beta cell destruction in autoimmune diabetes is accompanied by the presence of autoantibodies and autoreactive T cells against beta cell antigens…”
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