Search Results - "Fuchs, Sébastien"

Genetic Variant of the Renin-Angiotensin System and Diabetes Influences Blood Pressure Response to Angiotensin Receptor Blockers by Konoshita, Tadashi, Kato, Norihiro, Fuchs, Sébastien, Mizuno, Shinichi, Aoyama, Chikako, Motomura, Makoto, Makino, Yasukazu, Wakahara, Shigeyuki, Inoki, Isao, Miyamori, Isamu, Pinet, Florence

“…OBJECTIVE: Recent studies have proven the favorable effects of angiotensin receptor blockers (ARBs) on cardiovascular and renal disorders. However,…”
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A Highly Stereoselective Divergent Synthesis of Bicyclic Models of Photoreactive Sesquiterpene Lactones by Fuchs, Sébastien, Berl, Valérie, Lepoittevin, Jean-Pierre

“…Sesquiterpene lactones are natural stereochemically pure compounds, which show a number of biological activities. In order to study the reactivity of…”
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Chronic Actinic Dermatitis to Sesquiterpene Lactones: [2+2] Photoreaction Toward Thymidine of (+) and (−) α-Methylene-Hexahydrobenzofuranone with a cis Ring Junction by Fuchs, Sébastien, Berl, Valérie, Lepoittevin, Jean-Pierre

“…(+) and (−) α‐methylene‐hexahydrobenzofuranone derivatives with a stereochemically pure cis ring junction were used as models of sesquiterpene lactones to…”
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A proximal direct repeat motif characterized as a negative regulatory element in the human renin gene by Konoshita, Tadashi, Fuchs, Sébastien, Makino, Yasukazu, Wakahara, Shigeyuki, Miyamori, Isamu

“…The regulation of renin gene expression is thought to be fundamental to regulation of the total renin–angiotensin system. The human renin gene contains a…”
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Implication of Ref-1 in the repression of renin gene transcription by intracellular calcium by Fuchs, Sébastien, Philippe, Josette, Corvol, Pierre, Pinet, Florence

“…OBJECTIVEThe production of renin, which catalyzes the rate-limiting step of the renin–angiotensin system, is tightly regulated by intracellular second…”
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A modern understanding of the traditional and nontraditional biological functions of angiotensin-converting enzyme by Bernstein, Kenneth E, Ong, Frank S, Blackwell, Wendell-Lamar B, Shah, Kandarp H, Giani, Jorge F, Gonzalez-Villalobos, Romer A, Shen, Xiao Z, Fuchs, Sebastien, Touyz, Rhian M

“…Angiotensin-converting enzyme (ACE) is a zinc-dependent peptidase responsible for converting angiotensin I into the vasoconstrictor angiotensin II. However,…”
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Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease by Koronyo-Hamaoui, Maya, Sheyn, Julia, Hayden, Eric Y, Li, Songlin, Fuchs, Dieu-Trang, Regis, Giovanna C, Lopes, Dahabada H J, Black, Keith L, Bernstein, Kenneth E, Teplow, David B, Fuchs, Sebastien, Koronyo, Yosef, Rentsendorj, Altan

“…Targeted overexpression of angiotensin-converting enzyme (ACE), an amyloid-β protein degrading enzyme, to brain resident microglia and peripheral…”
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Angiotensin-converting enzyme enhances the oxidative response and bactericidal activity of neutrophils by Khan, Zakir, Shen, Xiao Z., Bernstein, Ellen A., Giani, Jorge F., Eriguchi, Masahiro, Zhao, Tuantuan V., Gonzalez-Villalobos, Romer A., Fuchs, Sebastien, Liu, George Y., Bernstein, Kenneth E.

“…Angiotensin-converting enzyme (ACE) inhibitors are widely used to reduce blood pressure. Here, we examined if an ACE is important for the antibacterial…”
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Angiotensin Type 1 Receptor Inhibition Enhances the Extinction of Fear Memory by Marvar, Paul J, Goodman, Jared, Fuchs, Sebastien, Choi, Dennis C, Banerjee, Sunayana, Ressler, Kerry J

“…Background The current effective treatment options for posttraumatic stress disorder (PTSD) are limited, and therefore the need to explore new treatment…”
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The absence of intrarenal ACE protects against hypertension by Gonzalez-Villalobos, Romer A, Janjoulia, Tea, Fletcher, Nicholas K, Giani, Jorge F, Nguyen, Mien T X, Riquier-Brison, Anne D, Seth, Dale M, Fuchs, Sebastien, Eladari, Dominique, Picard, Nicolas, Bachmann, Sebastian, Delpire, Eric, Peti-Peterdi, Janos, Navar, L Gabriel, Bernstein, Kenneth E, McDonough, Alicia A

“…Activation of the intrarenal renin-angiotensin system (RAS) can elicit hypertension independently from the systemic RAS. However, the precise mechanisms by…”
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Overexpression of the C-domain of angiotensin-converting enzyme reduces melanoma growth by stimulating M1 macrophage polarization by Khan, Zakir, Cao, Duo-Yao, Giani, Jorge F., Bernstein, Ellen A., Veiras, Luciana C., Fuchs, Sebastien, Wang, Yizhou, Peng, Zhenzi, Kalkum, Markus, Liu, George Y., Bernstein, Kenneth E.

“…Angiotensin-converting enzyme (ACE) can hydrolyze many peptides and plays a central role in controlling blood pressure. Moreover, ACE overexpression in…”
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Expression of Renin in Large Arteries Outside the Kidney Revealed by Human Renin Promoter/LacZ Transgenic Mouse by Fuchs, Sébastien, Germain, Stéphane, Philippe, Josette, Corvol, Pierre, Pinet, Florence

“…Renin plays a central role in controlling blood pressure as it catalyzes the first step in the production of angiotensin II. The aim of this study was to…”
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The Absence of the ACE N-Domain Decreases Renal Inflammation and Facilitates Sodium Excretion during Diabetic Kidney Disease by Eriguchi, Masahiro, Bernstein, Ellen A, Veiras, Luciana C, Khan, Zakir, Cao, Duo Yao, Fuchs, Sebastien, McDonough, Alicia A, Toblli, Jorge E, Gonzalez-Villalobos, Romer A, Bernstein, Kenneth E, Giani, Jorge F

“…Recent evidence emphasizes the critical role of inflammation in the development of diabetic nephropathy. Angiotensin-converting enzyme (ACE) plays an active…”
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Troponin T as a marker of differentiation revealed by proteomic analysis in renal arterioles by Pinet, Florence, Poirier, Florence, Fuchs, Sébastien, Tharaux, Pierre‐Louis, Caron, Michel, Corvol, Pierre, Michel, Jean‐Baptiste, Joubert‐Caron, Raymonde

“…Renovascular hypertension is characterized by stenosis of the renal artery and high plasma renin levels. The renal phenotype is characterized by high levels of…”
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Functionality of two new polymorphisms in the human renin gene enhancer region by Fuchs, Sébastien, Philippe, Josette, Germain, Stephane, Mathieu, Flavie, Jeunemaitre, Xavier, Corvol, Pierre, Pinet, Florence

“…BACKGROUND The production of renin, which catalyses the rate-limiting step of the renin–angiotensin system, is strongly stimulated by a 225 bp enhancer element…”
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The effects of enhancing angiotensin converting enzyme in myelomonocytes on ameliorating Alzheimer's-related disease and preserving cognition by Danziger, Ron, Fuchs, Dieu-Trang, Koronyo, Yosef, Rentsendorj, Altan, Sheyn, Julia, Hayden, Eric Y, Teplow, David B, Black, Keith L, Fuchs, Sebastien, Bernstein, Kenneth E, Koronyo-Hamaoui, Maya

“…This review examines the role of angiotensin-converting enzyme (ACE) in the context of Alzheimer's disease (AD) and its potential therapeutic value. ACE is…”
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Angiotensin-Converting Enzyme C-Terminal Catalytic Domain Is the Main Site of Angiotensin I Cleavage In Vivo by Fuchs, Sebastien, Xiao, Hong D, Hubert, Christine, Michaud, Annie, Campbell, Duncan J, Adams, Jonathan W, Capecchi, Mario R, Corvol, Pierre, Bernstein, Kenneth E

“…Angiotensin-converting enzyme (ACE) plays a central role in the production of the vasoconstrictor angiotensin II. ACE is a single polypeptide, but it contains…”
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Rapid Loss and Recovery of Vision Following Steroid Treatment in Orbital Myositis: A Case Report by Davis, Gavin, Li, Kin, Fuchs, Sebastien, Pan, Andrew

“…A 65-year-old African American man initially presented to the emergency department complaining of headaches, retro-orbital pressure, decreased vision, white…”
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Different in vivo functions of the two catalytic domains of angiotensin-converting enzyme (ACE) by Bernstein, Kenneth E, Shen, Xiao Z, Gonzalez-Villalobos, Romer A, Billet, Sandrine, Okwan-Duodu, Derick, Ong, Frank S, Fuchs, Sebastien

“…Angiotensin-converting enzyme (ACE) can cleave angiotensin I, bradykinin, neurotensin and many other peptide substrates in vitro . In part, this is due to the…”
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A Novel Distal Enhancer Confers Chorionic Expression on the Human Renin Gene by Germain, Stéphane, Bonnet, Fabrice, Philippe, Josette, Fuchs, Sébastien, Corvol, Pierre, Pinet, Florence

“…Renin catalyzes the rate-limiting step of the renin-angiotensin system, which regulates blood pressure and electrolyte homeostasis. To determine cell-specific…”
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