Search Results - "Füchtbauer, Anders Foller"

Flexibility and Preorganization of Fluorescent Nucleobase-Pyrene Conjugates Control DNA and RNA Recognition by Ban, Željka, Matić, Josipa, Žinić, Biserka, Füchtbauer, Anders Foller, Wilhelmsson, L Marcus, Piantanida, Ivo

“…We synthesized a new amino acid-fluorescent nucleobase derivative (qAN1-AA) and from it two new fluorescent nucleobase-fluorophore (pyrene) conjugates, whereby…”
Get full text

Toward Complete Sequence Flexibility of Nucleic Acid Base Analogue FRET by Wranne, Moa S, Füchtbauer, Anders Foller, Dumat, Blaise, Bood, Mattias, El-Sagheer, Afaf H, Brown, Tom, Gradén, Henrik, Grøtli, Morten, Wilhelmsson, L. Marcus

“…Förster resonance energy transfer (FRET) using fluorescent base analogues is a powerful means of obtaining high-resolution nucleic acid structure and dynamics…”
Get full text

Fluorescent RNA cytosine analogue – an internal probe for detailed structure and dynamics investigations by Füchtbauer, Anders Foller, Preus, Søren, Börjesson, Karl, McPhee, Scott A., Lilley, David M. J., Wilhelmsson, L. Marcus

“…The bright fluorescent cytosine analogue tC O stands out among fluorescent bases due to its virtually unquenched fluorescence emission in duplex DNA. However,…”
Get full text

Sulfone-based human liver pyruvate kinase inhibitors – Design, synthesis and in vitro bioactivity by Matić, Josipa, Akladios, Fady, Battisti, Umberto Maria, Håversen, Liliana, Nain-Perez, Amalyn, Füchtbauer, Anders Foller, Kim, Woonghee, Monjas, Leticia, Rivero, Alexandra Rodriguez, Borén, Jan, Mardinoglu, Adil, Uhlen, Mathias, Grøtli, Morten

“…Non-alcoholic fatty liver disease (NAFLD) is a prevalent pathological condition characterised by the accumulation of fat in the liver. Almost one-third of the…”
Get full text

Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase by Nain-Perez, Amalyn, Foller Füchtbauer, Anders, Håversen, Liliana, Lulla, Aleksei, Gao, Chunxia, Matic, Josipa, Monjas, Leticia, Rodríguez, Alexandra, Brear, Paul, Kim, Woonghee, Hyvönen, Marko, Borén, Jan, Mardinoglu, Adil, Uhlen, Mathias, Grøtli, Morten

“…Liver pyruvate kinase (PKL) is a major regulator of metabolic flux and ATP production during liver cell glycolysis and is considered a potential drug target…”
Get full text

Studying Z-DNA and B- to Z-DNA transitions using a cytosine analogue FRET-pair by Dumat, Blaise, Larsen, Anders Foller, Wilhelmsson, L Marcus

“…Herein, we report on the use of a tricyclic cytosine FRET pair, incorporated into DNA with different base pair separations, to study Z-DNA and B-Z DNA…”
Get full text

Interbase FRET in RNA: from A to Z by Füchtbauer, Anders F, Wranne, Moa S, Bood, Mattias, Weis, Erik, Pfeiffer, Pauline, Nilsson, Jesper R, Dahlén, Anders, Grøtli, Morten, Wilhelmsson, L Marcus

“…Abstract Interbase FRET can reveal highly detailed information about distance, orientation and dynamics in nucleic acids, complementing the existing structure…”
Get full text

Getting DNA and RNA out of the dark with 2CNqA: a bright adenine analogue and interbase FRET donor by Wypijewska del Nogal, Anna, Füchtbauer, Anders F, Bood, Mattias, Nilsson, Jesper R, Wranne, Moa S, Sarangamath, Sangamesh, Pfeiffer, Pauline, Rajan, Vinoth Sundar, El-Sagheer, Afaf H, Dahlén, Anders, Brown, Tom, Grøtli, Morten, Wilhelmsson, L Marcus

“…Abstract With the central role of nucleic acids there is a need for development of fluorophores that facilitate the visualization of processes involving…”
Get full text

Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base analogue by Bood, Mattias, Füchtbauer, Anders F, Wranne, Moa S, Ro, Jong Jin, Sarangamath, Sangamesh, El-Sagheer, Afaf H, Rupert, Déborah L M, Fisher, Rachel S, Magennis, Steven W, Jones, Anita C, Höök, Fredrik, Brown, Tom, Kim, Byeang Hyean, Dahlén, Anders, Wilhelmsson, L Marcus, Grøtli, Morten

“…Emissive base analogs are powerful tools for probing nucleic acids at the molecular level. Herein we describe the development and thorough characterization of…”
Get full text

Second-Generation Fluorescent Quadracyclic Adenine Analogues: Environment-Responsive Probes with Enhanced Brightness by Dumat, Blaise, Bood, Mattias, Wranne, Moa S., Lawson, Christopher P., Larsen, Anders Foller, Preus, Søren, Streling, Jens, Gradén, Henrik, Wellner, Eric, Grøtli, Morten, Wilhelmsson, L. Marcus

“…Fluorescent base analogues comprise a group of increasingly important molecules for the investigation of nucleic acid structure, dynamics, and interactions…”
Get full text

Synthesis, oligonucleotide incorporation and fluorescence properties in DNA of a bicyclic thymine analogue by Lawson, Christopher P., Füchtbauer, Anders F., Wranne, Moa S., Giraud, Tristan, Floyd, Thomas, Dumat, Blaise, Andersen, Nicolai K., H. El-Sagheer, Afaf, Brown, Tom, Gradén, Henrik, Wilhelmsson, L. Marcus, Grøtli, Morten

“…Fluorescent base analogues (FBAs) have emerged as a powerful class of molecular reporters of location and environment for nucleic acids. In our overall mission…”
Get full text

Development of bright fluorescent quadracyclic adenine analogues: TDDFT-calculation supported rational design by Foller Larsen, Anders, Dumat, Blaise, Wranne, Moa S., Lawson, Christopher P., Preus, Søren, Bood, Mattias, Gradén, Henrik, Marcus Wilhelmsson, L., Grøtli, Morten

“…Fluorescent base analogues (FBAs) comprise a family of increasingly important molecules for the investigation of nucleic acid structure and dynamics. We…”
Get full text

Lighting Up DNA with the Environment‐Sensitive Bright Adenine Analogue qAN4 by Füchtbauer, Anders F., Wranne, Moa S., Sarangamath, Sangamesh, Bood, Mattias, El‐Sagheer, Afaf H., Brown, Tom, Gradén, Henrik, Grøtli, Morten, Wilhelmsson, L. Marcus

“…The fluorescent adenine analogue qAN4 was recently shown to possess promising photophysical properties, including a high brightness as a monomer. Here we…”
Get full text