Search Results - "Fu, Yu V"
-
1
Selective Bypass of a Lagging Strand Roadblock by the Eukaryotic Replicative DNA Helicase
Published in Cell (16-09-2011)“…The eukaryotic replicative DNA helicase, CMG, unwinds DNA by an unknown mechanism. In some models, CMG encircles and translocates along one strand of DNA while…”
Get full text
Journal Article -
2
Microbe social skill: the cell-to-cell communication between microorganisms
Published in Science bulletin (Beijing) (15-04-2017)“…Although microbes primarily are single-cell organisms, they are not isolated individuals. Microbes use various means to communicate with one another. Based on…”
Get full text
Journal Article -
3
Fine-tuning the expression of target genes using a DDI2 promoter gene switch in budding yeast
Published in Scientific reports (29-08-2019)“…Tuned gene expression is crucial to the proper growth and response to the environmental changes of an organism. To enable tunable gene expression as designed…”
Get full text
Journal Article -
4
Rad5 coordinates translesion DNA synthesis pathway by recognizing specific DNA structures in saccharomyces cerevisiae
Published in Current genetics (01-08-2018)“…DNA repair is essential to maintain genome integrity. In addition to various DNA repair pathways dealing with specific types of DNA lesions, DNA damage…”
Get full text
Journal Article -
5
Using single-molecule approach to visualize the nucleosome assembly in yeast nucleoplasmic extracts
Published in Science bulletin (Beijing) (30-03-2017)“…In eukaryotic cells, the smallest subunit of chromatin is the nucleosome, which consists of a segment of DNA wound on histone protein cores. Despite many years…”
Get full text
Journal Article -
6
Gut microbiota‐CRAMP axis shapes intestinal barrier function and immune responses in dietary gluten‐induced enteropathy
Published in EMBO molecular medicine (09-08-2021)“…In the gut, cathelicidin‐related antimicrobial peptide (CRAMP) has been largely described for its anti‐infective activities. With an increasing recognition of…”
Get full text
Journal Article -
7
A novel cecropin B-derived peptide with antibacterial and potential anti-inflammatory properties
Published in PeerJ (San Francisco, CA) (25-07-2018)“…Cecropins, originally found in insects, are a group of cationic antimicrobial peptides. Most cecropins have an amphipathic N-terminal segment and a largely…”
Get full text
Journal Article -
8
Single cell tells the developmental story
Published in Science bulletin (Beijing) (01-09-2016)“…Stem cells are undifferentiated cells that retain the ability to self-renew and differentiate into specialized cells, offering a promising resource to generate…”
Get full text
Journal Article -
9
A Peptide from Budding Yeast GAPDH Serves as a Promising Antifungal against Cryptococcus neoformans
Published in Microbiology spectrum (23-02-2022)“…Infection of Cryptococcus neoformans is one of the leading causes of morbidity and mortality, particularly among immunocompromised patients. However, currently…”
Get full text
Journal Article -
10
Utilizing Biotinylated Proteins Expressed in Yeast to Visualize DNA-Protein Interactions at the Single-Molecule Level
Published in Frontiers in microbiology (24-10-2017)“…Much of our knowledge in conventional biochemistry has derived from bulk assays. However, many stochastic processes and transient intermediates are hidden when…”
Get full text
Journal Article -
11
Yeast Nucleoplasmic Extracts and an Application to Visualize Chromatin Assembly on Single Molecules of DNA
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2021)“…In eukaryotic cells, the genomic DNA is packaged into chromatin, the basic unit of which is the nucleosome. Studying the mechanism of chromatin formation under…”
Get more information
Journal Article -
12
Scarless Genomic Protein Labeling in Saccharomyces cerevisiae
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2021)“…Labeling a protein of interest is widely used to examine its quantity, modification, localization, and dynamics in the budding yeast Saccharomyces cerevisiae…”
Get more information
Journal Article -
13
A Peptide Derived from GAPDH Enhances Resistance to DNA Damage in Saccharomyces cerevisiae Cells
Published in Applied and environmental microbiology (22-02-2022)“…Social behaviors do not exist only in higher organisms but are also present in microbes that interact for the common good. Here, we report that budding yeast…”
Get full text
Journal Article -
14
Antifungal Peptide SP1 Damages Polysaccharide Capsule of Cryptococcus neoformans and Enhances Phagocytosis of Macrophages
Published in Microbiology spectrum (14-03-2023)“…Cryptococcus neoformans is a fungal pathogen which causes nearly half a million deaths worldwide each year. Under host-relevant conditions, it produces a…”
Get full text
Journal Article -
15
The application of thermophilic DNA primase TtDnaG2 to DNA amplification
Published in Scientific reports (09-10-2017)“…For DNA replication in vivo , DNA primase uses a complementary single-stranded DNA template to synthesize RNA primers ranging from 4 to 20 nucleotides in…”
Get full text
Journal Article -
16
DNA Replication: Metazoan Sld3 Steps Forward
Published in Current biology (22-06-2010)“…In yeast, phosphorylation of the Sld3 protein by cyclin-dependent kinases is essential for replication initiation. In metazoans, three potential Sld3…”
Get full text
Journal Article -
17
New insights in pre-replication complex formation with single-molecule visualization
Published in Science bulletin (Beijing) (01-06-2015)Get full text
Journal Article -
18
Nonequilibrium and nonlinear kinetics as key determinants for bistability in fission yeast G2-M transition
Published 30-10-2016“…A living cell is an open, nonequilibrium biochemical system where ATP hydrolysis serves as the energy source for a wide range of intracellular processes,…”
Get full text
Journal Article