Search Results - "Fu, Yingxue"
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1
Large-scale exploration and analysis of drug combinations
Published in Bioinformatics (Oxford, England) (15-06-2015)“…Drug combinations are a promising strategy for combating complex diseases by improving the efficacy and reducing corresponding side effects. Currently, a…”
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2
Treadmill training improves lung function and inhibits alveolar cell apoptosis in spinal cord injured rats
Published in Scientific reports (27-04-2024)“…Secondary lung injury after SCI is a major cause of patient mortality, with apoptosis playing a key role. This study aimed to explore the impact of treadmill…”
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3
Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons
Published in Nature communications (10-04-2024)“…Autophagy is a conserved, catabolic process essential for maintaining cellular homeostasis. Malfunctional autophagy contributes to neurodevelopmental and…”
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4
An adaptive stress response that confers cellular resilience to decreased ubiquitination
Published in Nature communications (14-11-2023)“…Ubiquitination is a post-translational modification initiated by the E1 enzyme UBA1, which transfers ubiquitin to ~35 E2 ubiquitin-conjugating enzymes. While…”
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5
Network based approach to drug discovery: a mini review
Published in Mini reviews in medicinal chemistry (01-01-2015)“…With the rapid development of high-throughput genomic technologies and the accumulation of genome-wide datasets for human disease, it has been shown that using…”
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6
PEAC: An Ultrasensitive and Cost-Effective MRD Detection System in Non-small Cell Lung Cancer Using Plasma Specimen
Published in Frontiers in medicine (03-03-2022)“…Circulating tumor DNA (ctDNA), a tumor-derived fraction of cell-free DNA (cfDNA), has emerged as a promising marker in targeted therapy, immunotherapy, and…”
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Integrated Multiomics Analyses Revealing Different Molecular Profiles Between Early- and Late-Stage Lung Adenocarcinoma
Published in Frontiers in oncology (21-10-2021)“…The molecular differences in genetic and epigenetic profiling between early-stage (ES) and late-stage (LS) lung adenocarcinoma (LUAD), which might help to…”
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8
Research on the Selective Electrocatalytic Reduction of SO2 to Recover S0 by Pb Electrode
Published in Metals (Basel ) (01-03-2023)“…Resource utilization of SO2 from flue gas is a key challenge for the green development of the smelting industry. Recovery of sulfur resources in the form of…”
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Deciphering the multicomponent synergy mechanism from a systems pharmacology perspective: Application to Gualou Xiebai Decoction for coronary heart disease
Published in Journal of functional foods (01-08-2018)“…[Display omitted] •GXD is a famous TCM formula to confront CHD.•ADME evaluation and PEA are employed to predict potential drug combination pairs.•The multiple…”
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10
Systematic Evaluation of the Diagnostic and Prognostic Significance of Competitive Endogenous RNA Networks in Prostate Cancer
Published in Frontiers in genetics (30-07-2020)“…Long non-coding RNA (lncRNA)-mediated competitive endogenous RNA (ceRNA) networks act as essential mechanisms in tumor initiation and progression, but their…”
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NOGEA: A Network-oriented Gene Entropy Approach for Dissecting Disease Comorbidity and Drug Repositioning
Published in Genomics, proteomics & bioinformatics (01-08-2021)“…Rapid development of high-throughput technologies has permitted the identification of an increasing number of disease-associated genes (DAGs), which are…”
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12
Systems pharmacology uncovers serotonergic pathway mediated psychotherapeutic effects of Lonicerae Japonicae Flos
Published in Journal of functional foods (01-09-2019)“…The concrete implementation process of systems pharmacology approach in treating psychiatric disorder with LJF (Lonicerae Japonicae Flos) is described as…”
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13
Systems-Mapping of Herbal Effects on Complex Diseases Using the Network-Perturbation Signatures
Published in Frontiers in pharmacology (18-10-2018)“…The herbs have proven to hold great potential to improve people's health and wellness during clinical practice over the past millennia. However, herbal…”
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14
Systems pharmacology for traditional Chinese medicine with application to cardio-cerebrovascular diseases
Published in Journal of Traditional Chinese Medical Sciences (01-10-2014)“…Identified as a treasure of natural herbal products, traditional Chinese medicine (TCM) has attracted extensive attention for their moderate treatment effect…”
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15
Ligustrazine suppresses neuron apoptosis via the Bax/Bcl‐2 and caspase‐3 pathway in PC12 cells and in rats with vascular dementia
Published in IUBMB life (01-01-2018)“…The aim of this study was to examine the comprehensive neuroprotective mechanism of ligustrazine, which is extracted from Ligusticum Chuanxiong Hort., against…”
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16
Prediction surface tension of ionic liquid–water mixtures using a hybrid group contribution and artificial neural network method
Published in Fluid phase equilibria (01-01-2023)“…In this work, a database was established to collect relevant surface tension data (4578 sets of data points in total) for 138 ionic liquids (ILs)-H2O hybrid…”
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17
A layered g-C3N4 support Single-Atom Fe-N4 catalyst derived from hemin to Activate PMS for Selective degradation of electron-rich compounds via singlet oxygen species
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-10-2023)“…A Layered g-C3N4 Support Single-Atom Fe-N4 Catalyst Derived from Hemin to Activate PMS for Selective Degradation of Aromatic Compounds via Singlet Oxygen…”
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18
Machine learning-assisted modeling study on the density and heat capacity of ionic liquid-organic solvent binary systems
Published in Journal of molecular liquids (15-11-2023)“…•Three methods are applied to predict the properties of the IL-organic solvent binary systems.•The SHAP method is employed to assess the importance of each…”
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19
Synergy of copper vacancies and amorphous regions in copper sulfides enables superior capacity for Hg0 adsorption
Published in Journal of hazardous materials (15-01-2024)“…Adsorption is a high-efficiency and low-cost approach to control elemental mercury emission from industrial flue gas. However, the adsorption capacity is…”
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Systematic understanding the mechanisms of vitiligo pathogenesis and its treatment by Qubaibabuqi formula
Published in Journal of ethnopharmacology (22-08-2016)“…Vitiligo is a depigmentation disorder, which results in substantial cosmetic disfigurement and poses a detriment to patients' physical as well as mental. Now…”
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