Search Results - "Fu, Xinhui"
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Stool DNA Test of Methylated Syndecan-2 for the Early Detection of Colorectal Neoplasia
Published in Cancer epidemiology, biomarkers & prevention (01-09-2017)“…Although the incidence of colorectal cancer is steadily increasing, screening for colorectal cancer with conventional approaches is not routinely performed in…”
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KRAS and PIK3CA bi-mutations predict a poor prognosis in colorectal cancer patients: A single-site report
Published in Translational oncology (01-12-2020)“…The coexistence of KRAS and PIK3CA mutations in cells implies potential synergistic hyperactivation of the Ras/MAPK and PI3K/Akt oncogenic pathways. Therefore,…”
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Novel Regulatory Roles of Wnt1 in Infection-Associated Colorectal Cancer
Published in Neoplasia (New York, N.Y.) (01-05-2018)“…Salmonella infection is a major public health concern, and colonization in humans can be chronic and increases the risk of cancers. Wnt signaling is a key…”
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Demographic trends and KRAS/BRAFV600E mutations in colorectal cancer patients of South China: A single‐site report
Published in International journal of cancer (01-05-2019)“…The incidence of colorectal cancer (CRC) is increasing in China. Here, we aimed to evaluate the latest demographic trends and KRAS/BRAF mutations status of…”
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Robust performance of a novel stool DNA test of methylated SDC2 for colorectal cancer detection: a multicenter clinical study
Published in Clinical epigenetics (30-10-2020)“…Stool DNA testing is an emerging and attractive option for colorectal cancer (CRC) screening. We previously evaluated the feasibility of a stool DNA (sDNA)…”
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The Spectrum, Tendency and Predictive Value of PIK3CA Mutation in Chinese Colorectal Cancer Patients
Published in Frontiers in oncology (26-03-2021)“…is a high-frequency mutation gene in colorectal cancer, while its prognostic value remains unclear. This study evaluated the mutation tendency, spectrum,…”
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Characteristics of late reformation and petroleum prospect of Carboniferous strata in the Bayanhot Basin, N. China
Published in Geological journal (Chichester, England) (01-10-2022)“…The Bayanhot Basin is located at the intersection of the Alxa Block, Ordos Basin, and Corridor Transitional Zone. Although the Carboniferous palaeo‐sedimentary…”
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CSN6‐SPOP‐HMGCS1 Axis Promotes Hepatocellular Carcinoma Progression via YAP1 Activation
Published in Advanced science (01-04-2024)“…Cholesterol metabolism has important roles in maintaining membrane integrity and countering the development of diseases such as obesity and cancers. Cancer…”
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NFκB1 and NFκBIA polymorphisms are associated with increased risk for sporadic colorectal cancer in a southern Chinese population
Published in PloS one (2011)“…Nuclear factor κB (NFκB) plays a key role in the regulation of apoptosis. The function of NFκB is inhibited by binding to NFκB inhibitor (IκB), and disruption…”
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Celecoxib Downregulates CD133 Expression Through Inhibition of the Wnt Signaling Pathway in Colon Cancer Cells
Published in Cancer investigation (01-02-2013)“…CD133-positive cancer stem cells in colon cancer are resistant to conventional chemotherapy. The aim of the present study was to investigate the effect of…”
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Nomograms for Prediction of Molecular Phenotypes in Colorectal Cancer
Published in OncoTargets and therapy (01-01-2020)“…Colorectal cancer (CRC) patients with different molecular phenotypes, including microsatellite instability (MSI), CpG island methylator phenotype (CIMP), and…”
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12
Mutations of p53 and K-ras correlate TF expression in human colorectal carcinomas: TF downregulation as a marker of poor prognosis
Published in International journal of colorectal disease (01-05-2011)“…Background Tissue factor (TF) is emphasized as the promising target in the future targeted therapy strategy for colorectal cancer (CRC). Recent evidence showed…”
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Expression of the phosphorylated MEK5 protein is associated with TNM staging of colorectal cancer
Published in BMC cancer (30-03-2012)“…Activation of MEK5 in many cancers is associated with carcinogenesis through aberrant cell proliferation. In this study, we determined the level of…”
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Trends in Molecular Testing of Lung Cancer in Mainland People’s Republic of China Over the Decade 2010 to 2019
Published in JTO clinical and research reports (01-04-2021)“…Lung cancer is the leading cause of cancer-related morbidity and mortality in the People’s Republic of China. Targeted therapies for patients with lung cancer,…”
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Functional variants of -1318T > G and -673C > T in c-Jun promoter region associated with increased colorectal cancer risk by elevating promoter activity
Published in Carcinogenesis (New York) (01-07-2011)“…C-Jun plays important roles in the development of multiple cancers, but no well-designed association studies have been conducted to assess the roles of its…”
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Construction of a SSH library of Aegiceras corniculatum under salt stress and expression analysis of four transcripts
Published in Plant science (Limerick) (01-07-2005)“…Suppressive subtractive hybridization was used to clone transcripts that showed enhanced expression during salt stress in the leaves of a salt-tolerant…”
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Expression patterns and polymorphisms of PTCH in Chinese hepatocellular carcinoma patients
Published in Experimental and molecular pathology (01-06-2008)“…Aberrant activation of Hedgehog signaling pathway leads to pathological consequences in a variety of human tumors. PTCH (PTCH1), the receptor of Hedgehog…”
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Protein diaphanous homolog 1 (Diaph1) promotes myofibroblastic activation of hepatic stellate cells by regulating Rab5a activity and TGFβ receptor endocytosis
Published in The FASEB journal (01-06-2020)“…TGFβ induces the differentiation of hepatic stellate cells (HSCs) into tumor‐promoting myofibroblasts but underlying mechanisms remain incompletely understood…”
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Prognosis and immunotherapy efficacy in dMMR&MSS colorectal cancer patients and an MSI status predicting model
Published in International journal of cancer (15-08-2024)“…The inconsistency between mismatch repair (MMR) protein immunohistochemistry (IHC) and microsatellite instability PCR (MSI‐PCR) methods has been widely…”
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Head-to-head comparative study: evaluating three panels for MSI-PCR testing in patients with colorectal and gastric cancer
Published in Journal of clinical pathology (27-11-2023)“…Due to the lack of large clinical cohorts in the Chinese populations with colorectal cancer (CRC) and gastric cancer (GC), there is no consensus among the…”
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