Search Results - "Fu, Rongfeng"

Multi-omics analysis of human mesenchymal stem cells shows cell aging that alters immunomodulatory activity through the downregulation of PD-L1 by Gao, Yuchen, Chi, Ying, Chen, Yunfei, Wang, Wentian, Li, Huiyuan, Zheng, Wenting, Zhu, Ping, An, Jinying, Duan, Yanan, Sun, Ting, Liu, Xiaofan, Xue, Feng, Liu, Wei, Fu, Rongfeng, Han, Zhibo, Zhang, Yingchi, Yang, Renchi, Cheng, Tao, Wei, Jun, Zhang, Lei, Zhang, Xiaomin

“…Mesenchymal stem cells (MSCs) possess potent immunomodulatory activity and have been extensively investigated for their therapeutic potential in treating…”
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Sex-specific impact on disease outcome and the mutational landscape in essential thrombocythemia: A retrospective cohort study by Chen, Jia, Dong, Huan, Li, Yang, Sun, Ting, Fu, Rongfeng, Liu, Xiaofan, Xue, Feng, Liu, Wei, Chen, Yunfei, Ju, Mankai, Dai, Xinyue, Chi, Ying, Wang, Wentian, Li, Huiyuan, Yang, Renchi, Zhang, Lei

“…The study design was approved by the Ethics Committee of the Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking…”
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Gadd45g insufficiency drives the pathogenesis of myeloproliferative neoplasms by Zhang, Peiwen, You, Na, Ding, Yiyi, Zhu, Wenqi, Wang, Nan, Xie, Yueqiao, Huang, Wanling, Ren, Qian, Qin, Tiejun, Fu, Rongfeng, Zhang, Lei, Xiao, Zhijian, Cheng, Tao, Ma, Xiaotong

“…Despite the identification of driver mutations leading to the initiation of myeloproliferative neoplasms (MPNs), the molecular pathogenesis of MPNs remains…”
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Paediatric essential thrombocythaemia: clinical and molecular features, diagnosis and treatment by Fu, Rongfeng, Zhang, Lei, Yang, Renchi

“…Summary The incidence of essential thrombocythaemia (ET) in children (age ≤18 years) is extremely low. The natural course of the disorder in children has not…”
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Targeted genome engineering in human induced pluripotent stem cells from patients with hemophilia B using the CRISPR-Cas9 system by Lyu, Cuicui, Shen, Jun, Wang, Rui, Gu, Haihui, Zhang, Jianping, Xue, Feng, Liu, Xiaofan, Liu, Wei, Fu, Rongfeng, Zhang, Liyan, Li, Huiyuan, Zhang, Xiaobing, Cheng, Tao, Yang, Renchi, Zhang, Lei

“…Replacement therapy for hemophilia remains a lifelong treatment. Only gene therapy can cure hemophilia at a fundamental level. The clustered regularly…”
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Multi-omics differences in the bone marrow between essential thrombocythemia and prefibrotic primary myelofibrosis by Zhang, Anqi, Sun, Ting, Yu, Dandan, Fu, Rongfeng, Liu, Xiaofan, Xue, Feng, Liu, Wei, Ju, Mankai, Dai, Xinyue, Dong, Huan, Gu, Wenjing, Chen, Jia, Chi, Ying, Li, Huiyuan, Wang, Wentian, Yang, Renchi, Chen, Yunfei, Zhang, Lei

“…Essential thrombocythemia (ET) and prefibrotic primary myelofibrosis (pre-PMF) are Philadelphia chromosome-negative myeloproliferative neoplasms. These…”
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Multilevel defects in the hematopoietic niche in essential thrombocythemia by Sun, Ting, Ju, Mankai, Dai, Xinyue, Dong, Huan, Gu, Wenjing, Gao, Yuchen, Fu, Rongfeng, Liu, Xiaofan, Huang, Yueting, Liu, Wei, Ch, Ying, Wang, Wentian, Li, Huiyuan, Zhou, Yuan, Shi, Lihong, Yang, Renchi, Zhang, Lei

“…The role of the bone marrow niche in essential thrombocythemia (ET) remains unclear. Here, we observed multilevel defects in the hematopoietic niche of…”
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Genetically determined telomere length and risk for haematologic diseases: results from large prospective cohorts and Mendelian Randomization analysis by Li, Yang, Chen, Jia, Sun, Ting, Chen, Yunfei, Fu, Rongfeng, Liu, Xiaofan, Xue, Feng, Liu, Wei, Ju, Mankai, Dai, Xinyue, Dong, Huan, Li, Huiyuan, Wang, Wentian, Chi, Ying, Zhang, Lei

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Ropeginterferon alfa-2b shows anti-polycythaemia vera activity without causing clinically significant anaemia by Kirito, Keita, Qin, Albert, Suo, Shanshan, Fu, Rongfeng, Wu, Daoxiang, Sato, Toshiaki, Zagrijtschuk, Oleh, Shimoda, Kazuya, Komatsu, Norio, Jin, Jie

“…Anaemia could develop in polycythemia vera (PV) due to phlebotomy-caused iron-deficiency and cytotoxic effect of cytoreductive therapy. Ropeginterferon alfa-2b…”
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Mutation profiling by targeted sequencing of “triple‐negative” essential thrombocythaemia patients by Ju, Mankai, Fu, Rongfeng, Li, Huiyuan, Liu, Xiaofan, Xue, Feng, Chen, Yunfei, Liu, Wei, Huang, Yueting, Zhang, Liyan, Yang, Renchi, Zhang, Lei

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A single-center study of patients with rare isolated acquired clotting factor deficiencies other than acquired hemophilia A by Yu, Dandan, Xue, Feng, Liu, Xiaofan, Chen, Yunfei, Fu, Rongfeng, Sun, Ting, Dai, Xinyue, Ju, Mankai, Dong, Huan, Yang, Renchi, Liu, Wei, Zhang, Lei

“…Isolated acquired clotting factor deficiencies (ACFDs) are mainly caused by the existence of anti-factor antibodies or adsorption of clotting factors onto…”
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Efficacy and safety of human umbilical cord-derived mesenchymal stem cells in the treatment of refractory immune thrombocytopenia: a prospective, single arm, phase I trial by Chen, Yunfei, Xu, Yanmei, Chi, Ying, Sun, Ting, Gao, Yuchen, Dou, Xueqing, Han, Zhibo, Xue, Feng, Li, Huiyuan, Liu, Wei, Liu, Xiaofan, Dong, Huan, Fu, Rongfeng, Ju, Mankai, Dai, Xinyue, Wang, Wentian, Ma, Yueshen, Song, Zhen, Gu, Jundong, Gong, Wei, Yang, Renchi, Zhang, Lei

“…Patients with refractory immune thrombocytopenia (ITP) frequently encounter substantial bleeding risks and demonstrate limited responsiveness to existing…”
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Reduced expression of MIR409‐3p in primary immune thrombocytopenia by Li, Huiyuan, Zhao, Haifeng, Xue, Feng, Zhang, Xian, Zhang, Donglei, Ge, Jing, Yang, Yanhui, Xuan, Min, Fu, Rongfeng, Yang, Renchi

“…Summary Primary immune thrombocytopenia (ITP) is an acquired autoimmune disease with many immune dysfunctions. MicroRNAs (miRNAs) are a class of non‐coding…”
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Decreased TLR4 expression on monocytes may cause regulatory T cells abnormality in patients with primary immune thrombocytopenia by Hao, Yating, Li, Huiyuan, Li, Yang, Lyu, Mingen, Zhang, Donglei, Fu, Rongfeng, Guan, Yue, Wang, Shixuan, Sun, Boyang, Dou, Xueqing, Yang, Renchi

“…Primary immune thrombocytopenia (ITP) is an autoimmune disease with many immune dysfunctions including T helper type 1 cell (Th1) polarization and regulatory T…”
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External validation and clinical evaluation of the International Prognostic Score of Thrombosis for Essential Thrombocythemia (IPSET-thrombosis) in a large cohort of Chinese patients by Fu, Rongfeng, Xuan, Min, Lv, Cuicui, Zhang, Liyan, Li, Huiyuan, Zhang, Xian, Zhang, Donglei, Sun, Tiantian, Xue, Feng, Liu, Xiaofan, Liang, Haoyue, Zhang, Lei, Yang, Renchi

“…Objectives In patients with essential thrombocythemia (ET), vascular complications contribute to both morbidity and mortality. To better predict the occurrence…”
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Immune thrombocytopenia in the elderly: clinical course in 525 patients from a single center in China by Zhou, Hu, Fu, Rongfeng, Wang, Hongmei, Zhou, Fangfang, Li, Huiyuan, Zhou, Zeping, Zhang, Lei, Yang, Renchi

“…Immune thrombocytopenia (ITP), often diagnosed in the elderly, is a hematologic disorder induced by autoimmune mechanism. In this retrospective study, we…”
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Molecular Analysis of JAK2V617F-Positive Myeloproliferative Neoplasms Reveals Wnt/β-Catenin As a Potential Target for Therapy by Wenjing, Gu, Tong, Jingyuan, Fu, Rongfeng, Shi, Lihong, Zhang, Lei

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Sex-Specific Impact on Disease Outcome and Mutational Landscape in Essential Thrombocythemia by Jia, Chen, Dong, Huan, Sun, Ting, Fu, Rongfeng, Yang, Renchi, Zhang, Lei

“…Background:Male sex has been confirmed as an independent risk factor on survival effect in patients withessential thrombocythemia by mutation-enhanced…”
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An Innovative Dynamic Nomogram for Stratifying Survival Prognosis in Essential Thrombocythemia Patients with a History of Thrombosis by Jia, Chen, Sun, Ting, Fu, Rongfeng, Dong, Huan, Yang, Renchi, Zhang, Lei

“…Background:Essential thrombocythemia (ET) with a previous history of thrombosis was classified as high risk according to the revised International Prognostic…”
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Clinical and molecular characteristics of forty Chinese children with essential thrombocythemia: A single‐center, retrospective analysis by Zhang, Luyang, Chen, Xiaoli, Hu, Tianyuan, Xu, Zefeng, Yang, Wenyu, Fu, Rongfeng, Zhang, Lei, Zhu, Xiaofan

“…Summary Due to the infrequency of essential thrombocythemia (ET) in children, little is known about its pathophysiological mechanism. To learn about the…”
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