Search Results - "Fu, Liezhen"
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Histone methyltransferase Dot1L is a coactivator for thyroid hormone receptor during Xenopus development
Published in The FASEB journal (01-11-2017)“…Histone modifications are associated with transcriptional regulation by diverse transcription factors. Genome‐wide correlation studies have revealed that…”
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The Sox transcriptional factors: Functions during intestinal development in vertebrates
Published in Seminars in cell & developmental biology (01-03-2017)“…The intestine has long been studied as a model for adult stem cells due to the life-long self-renewal of the intestinal epithelium through the proliferation of…”
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Thyroid hormone activates Xenopus MBD3 gene via an intronic TRE in vivo
Published in Frontiers in bioscience (01-01-2020)“…Thyroid hormone (T3) is important for adult organ function and vertebrate development. Amphibian metamorphosis is totally dependent on T3 and can be easily…”
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4
Competitive PCR with dual fluorescent primers enhances the specificity and reproducibility of genotyping animals generated from genome editing
Published in Cell & bioscience (11-05-2023)“…Targeted genome editing is a powerful tool for studying gene function in almost every aspect of biological and pathological processes. The most widely used…”
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Functional Studies of Transcriptional Cofactors via Microinjection-Mediated Gene Editing in Xenopus
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…The anuran Xenopus laevis has been studied for decades as a model for vertebrate cell and developmental biology. More recently, the highly related species…”
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Genome-wide identification of thyroid hormone receptor targets in the remodeling intestine during Xenopus tropicalis metamorphosis
Published in Scientific reports (25-07-2017)“…Thyroid hormone (T3) affects development and metabolism in vertebrates. We have been studying intestinal remodeling during T3-dependent Xenopus metamorphosis…”
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Thyroid hormone receptor knockout prevents the loss of Xenopus tail regeneration capacity at metamorphic climax
Published in Cell & bioscience (23-02-2023)“…Animal regeneration is the natural process of replacing or restoring damaged or missing cells, tissues, organs, and even entire body to full function. Studies…”
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Direct activation of tRNA methyltransferase-like 1 (Mettl1) gene by thyroid hormone receptor implicates a role in adult intestinal stem cell development and proliferation during Xenopus tropicalis metamorphosis
Published in Cell & bioscience (04-05-2020)“…Thyroid hormone (T3) plays an important role in vertebrate development. Compared to the postembryonic development of uterus-enclosed mammalian embryos,…”
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Liganded Thyroid Hormone Receptor Induces Nucleosome Removal and Histone Modifications to Activate Transcription during Larval Intestinal Cell Death and Adult Stem Cell Development
Published in Endocrinology (Philadelphia) (01-02-2012)“…Thyroid hormone (T3) plays an important role in regulating multiple cellular and metabolic processes, including cell proliferation, cell death, and energy…”
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10
Cytological and morphological analyses reveal distinct features of intestinal development during Xenopus tropicalis metamorphosis
Published in PloS one (10-10-2012)“…The formation and/or maturation of adult organs in vertebrates often takes place during postembryonic development, a period around birth in mammals when…”
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Thyroid hormone receptor actions on transcription in amphibia: The roles of histone modification and chromatin disruption
Published in Cell & bioscience (20-12-2012)“…Thyroid hormone (T3) plays diverse roles in adult organ function and during vertebrate development. The most important stage of mammalian development affected…”
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12
Simplifying Genotyping of Mutants from Genome Editing with a Parallel qPCR-Based iGenotype Index
Published in Cells (Basel, Switzerland) (01-01-2024)“…Targeted genome editing is a powerful tool in reverse genetic studies of gene function in many aspects of biological and pathological processes. The CRISPR/Cas…”
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Gene Expression Program Underlying Tail Resorption During Thyroid Hormone-Dependent Metamorphosis of the Ornamented Pygmy Frog Microhyla fissipes
Published in Frontiers in endocrinology (Lausanne) (2019)“…Thyroid hormone (T3) is essential for vertebrate development, especially during the so-called postembryonic development, a period around birth in mammals when…”
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The development of the adult intestinal stem cells: Insights from studies on thyroid hormone-dependent amphibian metamorphosis
Published in Cell & bioscience (06-09-2011)“…Adult organ-specific stem cells are essential for organ homeostasis and repair in adult vertebrates. The intestine is one of the best-studied organs in this…”
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Epigenetic regulation of thyroid hormone-induced adult intestinal stem cell development during anuran metamorphosis
Published in Cell & bioscience (28-11-2014)“…Epigenetic modifications of histones are emerging as key factors in gene regulation by diverse transcription factors. Their roles during vertebrate development…”
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Expression Profiling of Intestinal Tissues Implicates Tissue-Specific Genes and Pathways Essential for Thyroid Hormone-Induced Adult Stem Cell Development
Published in Endocrinology (Philadelphia) (01-11-2013)“…The study of the epithelium during development in the vertebrate intestine touches upon many contemporary aspects of biology: to name a few, the formation of…”
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Genome-wide identification of Xenopus matrix metalloproteinases: conservation and unique duplications in amphibians
Published in BMC genomics (17-02-2009)“…Matrix metalloproteinases (MMPs) are members of the superfamily of Zn2+ dependent extracellular or membrane-bound endopeptidases which have been implicated to…”
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Histone H3K79 methyltransferase Dot1L is directly activated by thyroid hormone receptor during Xenopus metamorphosis
Published in Cell & bioscience (16-07-2012)“…Thyroid hormone (T3) is important for adult organ function and vertebrate development. Amphibian metamorphosis is totally dependent on T3 and offers a unique…”
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Thyroid hormone-induced sonic hedgehog signal up-regulates its own pathway in a paracrine manner in the Xenopus laevis intestine during metamorphosis
Published in Developmental dynamics (01-02-2012)“…Background: During Xenopus laevis metamorphosis, Sonic hedgehog (Shh) is directly induced by thyroid hormone (TH) at the transcription level as one of the…”
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Spatio-temporal expression profile of stem cell-associated gene LGR5 in the intestine during thyroid hormone-dependent metamorphosis in Xenopus laevis
Published in PloS one (22-10-2010)“…The intestinal epithelium undergoes constant self-renewal throughout adult life across vertebrates. This is accomplished through the proliferation and…”
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