Search Results - "Fryer, Susanna"

Dynamic functional connectivity impairments in early schizophrenia and clinical high-risk for psychosis by Du, Yuhui, Fryer, Susanna L., Fu, Zening, Lin, Dongdong, Sui, Jing, Chen, Jiayu, Damaraju, Eswar, Mennigen, Eva, Stuart, Barbara, Loewy, Rachel L., Mathalon, Daniel H., Calhoun, Vince D.

“…Individuals at clinical high-risk (CHR) for psychosis are characterized by attenuated psychotic symptoms. Only a minority of CHR individuals convert to…”
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Cortical Thickness, Surface Area, and Volume of the Brain Reward System in Alcohol Dependence: Relationships to Relapse and Extended Abstinence by Durazzo, Timothy C., Tosun, Duygu, Buckley, Shannon, Gazdzinski, Stefan, Mon, Anderson, Fryer, Susanna L., Meyerhoff, Dieter J.

“…Background:  At least 60% of those treated for an alcohol use disorder will relapse. Empirical study of the integrity of the brain reward system (BRS) is…”
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Brain Age Gap in Early Illness Schizophrenia and the Clinical High-Risk Syndrome: Associations With Experiential Negative Symptoms and Conversion to Psychosis by Hua, Jessica P Y, Abram, Samantha V, Loewy, Rachel L, Stuart, Barbara, Fryer, Susanna L, Vinogradov, Sophia, Mathalon, Daniel H

“…Abstract Background and Hypothesis Brain development/aging is not uniform across individuals, spawning efforts to characterize brain age from a biological…”
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Blunted amygdala activity is associated with depression severity in treatment-resistant depression by Ferri, Jamie, Eisendrath, Stuart J., Fryer, Susanna L., Gillung, Erin, Roach, Brian J., Mathalon, Daniel H.

“…Up to 50% of individuals with major depressive disorder (MDD) do not recover after two antidepressant medication trials, and therefore meet the criteria for…”
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Age affects temporal response, but not durability, to serial ketamine infusions for treatment refractory depression by Pennybaker, Steven, Roach, Brian J., Fryer, Susanna L., Badathala, Anusha, Wallace, Art W., Mathalon, Daniel H., Marton, Tobias F.

“…Rationale Ketamine is a novel, rapid-acting antidepressant for treatment refractory depression (TRD); however, clinical durability is poor and treatment…”
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Doubling Down on Developing Reward System Neurobiology Markers of Antidepressant Treatment Response by Fryer, Susanna L.

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Thalamic dysconnectivity in the psychosis risk syndrome and early illness schizophrenia by Fryer, Susanna L, Ferri, Jamie M, Roach, Brian J, Loewy, Rachel L, Stuart, Barbara K, Anticevic, Alan, Ford, Judith M, Mathalon, Daniel H

“…Schizophrenia (SZ) is associated with thalamic dysconnectivity. Compared to healthy controls (HCs), individuals with SZ have hyperconnectivity with sensory…”
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Validation of ketamine as a pharmacological model of thalamic dysconnectivity across the illness course of schizophrenia by Abram, Samantha V., Roach, Brian J., Fryer, Susanna L., Calhoun, Vince D., Preda, Adrian, van Erp, Theo G. M., Bustillo, Juan R., Lim, Kelvin O., Loewy, Rachel L., Stuart, Barbara K., Krystal, John H., Ford, Judith M., Mathalon, Daniel H.

“…N -methyl-D-aspartate receptor (NMDAR) hypofunction is a leading pathophysiological model of schizophrenia. Resting-state functional magnetic resonance imaging…”
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Rich-club connectivity and structural connectome organization in youth at clinical high-risk for psychosis and individuals with early illness schizophrenia by Hua, Jessica P.Y., Cummings, Jennifer, Roach, Brian J., Fryer, Susanna L., Loewy, Rachel L., Stuart, Barbara K., Ford, Judith M., Vinogradov, Sophia, Mathalon, Daniel H.

“…Brain dysconnectivity has been posited as a biological marker of schizophrenia. Emerging schizophrenia connectome research has focused on rich-club…”
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Evaluation of Psychopathological Conditions in Children With Heavy Prenatal Alcohol Exposure by Fryer, Susanna L, McGee, Christie L, Matt, Georg E, Riley, Edward P, Mattson, Sarah N

“…This study compared the prevalence of psychopathological conditions in children with heavy prenatal alcohol exposure (N = 39) and nonexposed, typically…”
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Psychological Dimensions Relevant to Motivation and Pleasure in Schizophrenia by Abram, Samantha V, Weittenhiller, Lauren P, Bertrand, Claire E, McQuaid, John R, Mathalon, Daniel H, Ford, Judith M, Fryer, Susanna L

“…Motivation and pleasure deficits are common in schizophrenia, strongly linked with poorer functioning, and may reflect underlying alterations in brain…”
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Reduced higher-dimensional resting state fMRI dynamism in clinical high-risk individuals for schizophrenia identified by meta-state analysis by Mennigen, Eva, Miller, Robyn L., Rashid, Barnaly, Fryer, Susanna L., Loewy, Rachel L., Stuart, Barbara K., Mathalon, Daniel H., Calhoun, Vince D.

“…New techniques to investigate functional network connectivity in resting state functional magnetic resonance imaging data have recently emerged. One novel…”
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Cortical and subcortical brain morphometry abnormalities in youth at clinical high-risk for psychosis and individuals with early illness schizophrenia by Hua, Jessica P.Y., Loewy, Rachel L., Stuart, Barbara, Fryer, Susanna L., Niendam, Tara A., Carter, Cameron S., Vinogradov, Sophia, Mathalon, Daniel H.

“…•Compared clinical high-risk (CHR-P) and early illness schizophrenia (ESZ) profiles.•ESZ morphometric profiles differed from healthy controls (HC) and…”
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Relating Intrinsic Low-Frequency BOLD Cortical Oscillations to Cognition in Schizophrenia by Fryer, Susanna L, Roach, Brian J, Ford, Judith M, Turner, Jessica A, van Erp, Theo G M, Voyvodic, James, Preda, Adrian, Belger, Aysenil, Bustillo, Juan, O'Leary, Daniel, Mueller, Bryon A, Lim, Kelvin O, McEwen, Sarah C, Calhoun, Vince D, Diaz, Michelle, Glover, Gary, Greve, Douglas, Wible, Cynthia G, Vaidya, Jatin, Potkin, Steven G, Mathalon, Daniel H

“…The amplitude of low-frequency fluctuations (ALFF) in the blood oxygenation level-dependent (BOLD) signal during resting-state fMRI reflects the magnitude of…”
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Reduced Amplitude of Low-Frequency Brain Oscillations in the Psychosis Risk Syndrome and Early Illness Schizophrenia by Fryer, Susanna L, Roach, Brian J, Wiley, Katherine, Loewy, Rachel L, Ford, Judy M, Mathalon, Daniel H

“…Low-frequency oscillations (LFOs) of the blood oxygen level-dependent (BOLD) signal are gaining interest as potential biomarkers sensitive to neuropsychiatric…”
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Should I Stay or Should I Go? FMRI Study of Response Inhibition in Early Illness Schizophrenia and Risk for Psychosis by Fryer, Susanna L, Roach, Brian J, Ford, Judith M, Donaldson, Kayla R, Calhoun, Vince D, Pearlson, Godfrey D, Kiehl, Kent A, Srihari, Vinod H, McGlashan, Thomas H, Woods, Scott W, Mathalon, Daniel H

“…Abstract Response inhibition (RI) is a component of the cognitive control systems that support optimal cognition. Cognitive control deficits are well-described…”
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Neuroimaging and fetal alcohol spectrum disorders by Spadoni, Andrea D., McGee, Christie L., Fryer, Susanna L., Riley, Edward P.

“…Heavy prenatal alcohol exposure causes permanent structural alterations to the brain and can lead to numerous cognitive and behavioral outcomes. Consistent…”
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Advanced brain age correlates with greater rumination and less mindfulness in schizophrenia by Abram, Samantha V., Roach, Brian J., Hua, Jessica P.Y., Han, Laura K.M., Mathalon, Daniel H., Ford, Judith M., Fryer, Susanna L.

“…•Brain age was estimated from high-resolution anatomical scans and compared with chronological age.•Emotional well-being was derived from measures of…”
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Identifying functional network changing patterns in individuals at clinical high-risk for psychosis and patients with early illness schizophrenia: A group ICA study by Du, Yuhui, Fryer, Susanna L., Lin, Dongdong, Sui, Jing, Yu, Qingbao, Chen, Jiayu, Stuart, Barbara, Loewy, Rachel L., Calhoun, Vince D., Mathalon, Daniel H.

“…Although individuals at clinical high risk (CHR) for psychosis exhibit a psychosis-risk syndrome involving attenuated forms of the positive symptoms typical of…”
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Another Step Forward in Relating Facial and Brain Dysmorphologies Associated with Prenatal Alcohol Exposure by Fryer, Susanna L.

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