Search Results - "Fryer, A. A."

Criteria for the Research Institute for Fragrance Materials, Inc. (RIFM) safety evaluation process for fragrance ingredients by Api, A.M., Belsito, D., Bruze, M., Cadby, P., Calow, P., Dagli, M.L., Dekant, W., Ellis, G., Fryer, A.D., Fukayama, M., Griem, P., Hickey, C., Kromidas, L., Lalko, J.F., Liebler, D.C., Miyachi, Y., Politano, V.T., Renskers, K., Ritacco, G., Salvito, D., Schultz, T.W., Sipes, I.G., Smith, B., Vitale, D., Wilcox, D.K.

“…•This publication is designed to update the RIFM safety assessment process, which follows a series of decision trees.•This process incorporates advances in…”
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Evaluation of Different Interstimulus Rinse Protocols on Smoke Attribute Perception in Wildfire-Affected Wines by Fryer, Jenna A, Collins, Thomas S, Tomasino, Elizabeth

“…Wildfires produce smoke that can carry organic compounds to a vineyard, which are then absorbed by the grape berry and result in wines with elevated levels of…”
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Global mapping of RNA-chromatin contacts reveals a proximity-dominated connectivity model for ncRNA-gene interactions by Limouse, Charles, Smith, Owen K., Jukam, David, Fryer, Kelsey A., Greenleaf, William J., Straight, Aaron F.

“…Non-coding RNAs (ncRNAs) are transcribed throughout the genome and provide regulatory inputs to gene expression through their interaction with chromatin. Yet,…”
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Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma by Melchor, L, Brioli, A, Wardell, C P, Murison, A, Potter, N E, Kaiser, M F, Fryer, R A, Johnson, D C, Begum, D B, Hulkki Wilson, S, Vijayaraghavan, G, Titley, I, Cavo, M, Davies, F E, Walker, B A, Morgan, G J

“…Although intratumor heterogeneity has been inferred in multiple myeloma (MM), little is known about its subclonal phylogeny. To describe such phylogenetic…”
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Non‐bronchodilating mechanisms of tiotropium prevent airway hyperreactivity in a guinea‐pig model of allergic asthma by Buels, KS, Jacoby, DB, Fryer, AD

“…BACKGROUND AND PURPOSE Asthma is characterized by reversible bronchoconstriction and airway hyperreactivity. Although M3 muscarinic receptors mediate…”
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Epigenetic control of fetal gene expression by NAFEE, T. M, FARRELL, W. E, CARROLL, W. D, FRYER, A. A, ISMAIL, K. M. K

“…Each differentiated cell type has its own epigenetic signature, which reflects its genotype, developmental history, and environmental influences, and is…”
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Glutathione-S-transferase family of enzymes by Strange, R C, Spiteri, M A, Ramachandran, S, Fryer, A A

“…The loci encoding the glutathione-S-transferase (GST) enzymes comprise a large supergene family located on at least seven chromosomes. The function of the GST…”
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Route to improving Type 1 diabetes mellitus glycaemic outcomes: real‐world evidence taken from the National Diabetes Audit by Heald, A. H., Livingston, M., Fryer, A., Moreno, G. Y. C., Malipatil, N., Gadsby, R., Ollier, W., Lunt, M., Stedman, M., Young, R. J.

“…Aim To use general practice‐level data for England, available through the National Diabetes Audit, and primary care prescribing data to identify prescription…”
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Different Olfactory Percepts Evoked by Orthonasal and Retronasal Odorant Delivery by Hannum, Mackenzie, Stegman, Margaret A, Fryer, Jenna A, Simons, Christopher T

“…Abstract The Duality of Smell hypothesis suggests odorants delivered orthonasally elicit different sensations compared with those delivered retronasally…”
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Methylation of HOXA9 and ISL1 Predicts Patient Outcome in High-Grade Non-Invasive Bladder Cancer by Kitchen, Mark O, Bryan, Richard T, Haworth, Kim E, Emes, Richard D, Luscombe, Christopher, Gommersall, Lyndon, Cheng, K K, Zeegers, Maurice P, James, Nicholas D, Devall, Adam J, Fryer, Anthony A, Farrell, William E

“…Inappropriate DNA methylation is frequently associated with human tumour development, and in specific cases, is associated with clinical outcomes. Previous…”
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Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies by Wu, Pensee, Farrell, William E, Haworth, Kim E, Emes, Richard D, Kitchen, Mark O, Glossop, John R, Hanna, Fahmy W, Fryer, Anthony A

“…Several recent reports have described associations between gestational diabetes (GDM) and changes to the epigenomic landscape where the DNA samples were…”
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RIFM fragrance ingredient safety assessment, acetyl cedrene, CAS Registry Number 32388-55-9 by Api, A.M., Belsito, D., Botelho, D., Bruze, M., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Date, M., Dekant, W., Deodhar, C., Fryer, A.D., Jones, L., Joshi, K., Kumar, M., Lapczynski, A., Lavelle, M., Lee, I., Liebler, D.C., Moustakas, H., Na, M., Penning, T.M., Ritacco, G., Romine, J., Sadekar, N., Schultz, T.W., Selechnik, D., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Acetyl cedrene; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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Analysis of Retronasal Flavor Alterations in Smoke-Affected Wines and the Efficacy of Various Inter-Stimulus Rinse Protocols in Clearing Smoke-Related Attributes by Fryer, Jenna A., Tomasino, Elizabeth

“…Wildfires produce smoke, which can then encounter wine grapes, causing the fruit to absorb smoke-related volatile organic compounds. These compounds impact the…”
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Relationship Between Anemia and Mortality Outcomes in a National Acute Coronary Syndrome Cohort: Insights From the UK Myocardial Ischemia National Audit Project Registry by Mamas, Mamas A., Kwok, Chun Shing, Kontopantelis, Evangelos, Fryer, Anthony A., Buchan, Iain, Bachmann, Max O., Zaman, M. Justin, Myint, Phyo K.

“…Background We aim to determine the prevalence of anemia in acute coronary syndrome (ACS) patients and compare their clinical characteristics, management, and…”
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Monomeric C-Reactive Protein in Serum With Markedly Elevated CRP Levels Shares Common Calcium-Dependent Ligand Binding Properties With an in vitro Dissociated Form of C-Reactive Protein by Williams, Robert D, Moran, Jennifer A, Fryer, Anthony A, Littlejohn, Jamie R, Williams, Harry M, Greenhough, Trevor J, Shrive, Annette K

“…A monomeric form of C-reactive protein (CRP) which precipitates with cell wall pneumococcal C polysaccharide (CWPS) and retains the ability to reversibly bind…”
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Update to RIFM fragrance ingredient safety assessment, tricyclodecanyl acetate, CAS registry number 64001-15-6 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Tricyclodecanyl acetate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints…”
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Update to RIFM fragrance ingredient safety assessment, 1-naphthalenol, 1,2,3,4,4a,5,8,8a-octahydro-2,2,6,8-tetramethyl-, CAS Registry Number 103614-86-4 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•1-Naphthalenol, 1,2,3,4,4a,5,8,8a-octahydro-2,2,6,8-tetramethyl-; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health…”
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Update to RIFM fragrance ingredient safety assessment, (Z)-octadec-9-enol, CAS registry number 143-28-2 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•(Z)-Octadec-9-enol; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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RIFM fragrance ingredient safety assessment, nonanoyl 4-hydroxy-3-methoxybenzylamide, CAS Registry Number 2444-46-4 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Nonanoyl 4-hydroxy-3-methoxybenzylamide; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus…”
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RIFM fragrance ingredient safety assessment, linalyl formate, CAS registry number 115-99-1 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Linalyl formate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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