Search Results - "Fry, Norman K"
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Effectiveness of maternal pertussis vaccination in England: an observational study
Published in The Lancet (British edition) (25-10-2014)“…Summary Background In October, 2012, a pertussis vaccination programme for pregnant women was introduced in response to an outbreak across England. We aimed to…”
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Sustained Effectiveness of the Maternal Pertussis Immunization Program in England 3 Years Following Introduction
Published in Clinical infectious diseases (01-12-2016)“…The effectiveness of maternal immunization in preventing infant pertussis was first demonstrated in England, 1 year after the program using…”
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Characteristics of Invasive Pneumococcal Disease Caused by Emerging Serotypes After the Introduction of the 13-Valent Pneumococcal Conjugate Vaccine in England: A Prospective Observational Cohort Study, 2014–2018
Published in Clinical infectious diseases (05-11-2020)“…Abstract Background England is experiencing a rapid increase in invasive pneumococcal disease (IPD) caused by serotypes 8, 12F, and 9N; their clinical…”
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Increased Incidence of Invasive Pneumococcal Disease among Children after COVID-19 Pandemic, England
Published in Emerging infectious diseases (01-08-2022)“…During July–December 2021, after COVID-19 restrictions were removed in England, invasive pneumococcal disease incidence in children <15 years of age was higher…”
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Impact of the COVID-19 pandemic on Bordetella pertussis infections in England
Published in BMC public health (28-02-2022)“…In March 2020, England went into its first lockdown in response to the COVID-19 pandemic. Restrictions eased temporarily, followed by second and third waves in…”
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Pneumococcal carriage in children and their household contacts six years after introduction of the 13-valent pneumococcal conjugate vaccine in England
Published in PloS one (25-05-2018)“…In April 2010, 13-valent pneumococcal conjugate vaccine (PCV13) replaced PCV7 in the infant immunisation schedule in England and Wales. Despite limited…”
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Pertussis Prevention: Reasons for Resurgence, and Differences in the Current Acellular Pertussis Vaccines
Published in Frontiers in immunology (03-07-2019)“…Pertussis is an acute respiratory disease caused by . Due to its frequency and severity, prevention of pertussis has been considered an important public health…”
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Effectiveness of the 23-valent pneumococcal polysaccharide vaccine against vaccine serotype pneumococcal pneumonia in adults: A case-control test-negative design study
Published in PLoS medicine (23-10-2020)“…Vaccination with the 23-valent pneumococcal polysaccharide vaccine (PPV23) is available in the United Kingdom to adults aged 65 years or older and those in…”
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Effect of Pneumococcal Conjugate Vaccines on Pneumococcal Meningitis, England and Wales, July 1, 2000-June 30, 2016
Published in Emerging infectious diseases (01-09-2019)“…We describe the effects of the 7-valent (PCV7) and 13-valent (PCV13) pneumococcal conjugate vaccines on pneumococcal meningitis in England and Wales during…”
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Whole genome sequencing of Streptococcus pneumoniae: development, evaluation and verification of targets for serogroup and serotype prediction using an automated pipeline
Published in PeerJ (San Francisco, CA) (14-09-2016)“…Streptococcus pneumoniae typically express one of 92 serologically distinct capsule polysaccharide (cps) types (serotypes). Some of these serotypes are closely…”
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Effectiveness of 23-Valent Polysaccharide Pneumococcal Vaccine and Changes in Invasive Pneumococcal Disease Incidence from 2000 to 2017 in Those Aged 65 and Over in England and Wales
Published in EClinicalMedicine (01-12-2018)“…Invasive Pneumococcal Disease (IPD) is a major public health concern. The effectiveness of 23-valent polysaccharide pneumococcal vaccine (PPV23) against IPD in…”
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Acquisition and loss of virulence-associated factors during genome evolution and speciation in three clades of Bordetella species
Published in BMC genomics (30-09-2016)“…The genus Bordetella consists of nine species that include important respiratory pathogens such as the 'classical' species B. bronchiseptica, B. pertussis and…”
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Rapid Spread of Pneumococcal Nonvaccine Serotype 7C Previously Associated with Vaccine Serotype 19F, England and Wales
Published in Emerging infectious diseases (01-10-2018)“…We observed a sudden and rapid increase in rare invasive pneumococcal disease serotype 7C, from an annual average of 3 cases during 2000-01 through 2015-16 to…”
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Surveillance of Circulating Bordetella pertussis Strains in Europe during 1998 to 2015
Published in Journal of clinical microbiology (01-05-2018)“…One reason for increased pertussis incidence is the adaptation of to vaccine-induced immunity by modulating its genomic structure. This study, EUpert IV,…”
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Addition of neuA, the Gene Encoding N-Acylneuraminate Cytidylyl Transferase, Increases the Discriminatory Ability of the Consensus Sequence-Based Scheme for Typing Legionella pneumophila Serogroup 1 Strains
Published in Journal of Clinical Microbiology (01-06-2007)“…The standard sequence-based method for the typing of Legionella pneumophila serogroup 1 strains was extended by using the gspA and neuA alleles. The use of…”
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Accelerating control of pertussis in England and Wales
Published in Emerging infectious diseases (01-01-2012)“…Results of an accelerated pertussis vaccination schedule for infants introduced in 1990 in England and Wales were examined. Earlier scheduling and sustained…”
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Discovery and description of a new serogroup 7 Streptococcus pneumoniae serotype, 7D, and structural analysis of 7C and 7D
Published in Carbohydrate research (30-06-2018)“…Streptococcus pneumoniae is characterised into 92 serotypes based on antigenic reactions of commercial rabbit sera to the capsular polysaccharides. During…”
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A spitting image: molecular diagnostics applied to saliva enhance detection of Streptococcus pneumoniae and pneumococcal serotype carriage
Published in Frontiers in microbiology (17-04-2023)“…Despite strong historical records on the accuracy of saliva testing, oral fluids are considered poorly suited for pneumococcal carriage detection. We evaluated…”
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Changes in Genetic Diversity of the Bordetella pertussis Population in the United Kingdom between 1920 and 2006 Reflect Vaccination Coverage and Emergence of a Single Dominant Clonal Type
Published in Journal of Clinical Microbiology (01-03-2009)“…Pertussis (whooping cough) is a potentially fatal respiratory disease caused by the bacterium Bordetella pertussis. Despite effective vaccination programs,…”
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It Takes Two to Tango: Combining Conventional Culture With Molecular Diagnostics Enhances Accuracy of Streptococcus pneumoniae Detection and Pneumococcal Serogroup/Serotype Determination in Carriage
Published in Frontiers in microbiology (18-04-2022)“…The specificity of molecular methods for the detection of carriage is under debate. We propose a procedure for carriage surveillance and vaccine impact studies…”
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