Search Results - "Fry, Nicole L."

Triggered Dye Release via Photodissociation of Nitric Oxide from Designed Ruthenium Nitrosyls: Turn-ON Fluorescence Signaling of Nitric Oxide Delivery by Fry, Nicole L, Wei, Julia, Mascharak, Pradip K

“…Two new fluorescein-tethered nitrosyls derived from designed tetradentate ligands with carboxamido-N donors have been synthesized and characterized by…”
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Designed Iron Carbonyls as Carbon Monoxide (CO) Releasing Molecules: Rapid CO Release and Delivery to Myoglobin in Aqueous Buffer, and Vasorelaxation of Mouse Aorta by Gonzalez, Margarita A, Fry, Nicole L, Burt, Richard, Davda, Riddhi, Hobbs, Adrian, Mascharak, Pradip K

“…The physiological roles of CO in neurotransmission, vasorelaxation, and cytoprotective activities have raised interest in the design and syntheses of…”
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Photoactive Ruthenium Nitrosyls as NO Donors: How To Sensitize Them toward Visible Light by Fry, Nicole L, Mascharak, Pradip K

“…Nitric oxide (NO) can induce apoptosis (programmed cell death) at micromolar or higher doses. Although cell death via NO-induced apoptosis has been studied…”
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Oxidation-Induced Trapping of Drugs in Porous Silicon Microparticles by Fry, Nicole L, Boss, Gerry R, Sailor, Michael J

“…An approach for the preparation of an oxidized porous silicon microparticle drug delivery system that can provide efficient trapping and sustained release of…”
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Sensitization of Ruthenium Nitrosyls to Visible Light via Direct Coordination of the Dye Resorufin: Trackable NO Donors for Light-Triggered NO Delivery to Cellular Targets by Rose, Michael J, Fry, Nicole L, Marlow, Rebecca, Hinck, Lindsay, Mascharak, Pradip K

“…Three nitrosyl-dye conjugates, namely, [(Me2bpb)Ru(NO)(Resf)] (1-Resf), [(Me2bQb)Ru(NO)(Resf)] (2-Resf), and [((OMe)2bQb)Ru(NO)(Resf)] (3-Resf) have been…”
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Syntheses, Structures, and Properties of New Manganese Carbonyls as Photoactive CO-Releasing Molecules: Design Strategies That Lead to CO Photolability in the Visible Region by Gonzalez, Margarita A, Carrington, Samantha J, Fry, Nicole L, Martinez, Jose L, Mascharak, Pradip K

“…The unusual role of CO as a signaling molecule in several physiological pathways has spurred research in the area of synthesizing new CO-releasing molecules…”
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Photolability of NO in designed metal nitrosyls with carboxamido-N donors: a theoretical attempt to unravel the mechanism by Fry, Nicole L, Mascharak, Pradip K

“…During the past few years, photoactive metal nitrosyls (NO complexes of metals) have drawn attention as potential drugs for delivery of nitric oxide (NO) to…”
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Development of a cobinamide-based end-of-service-life indicator for detection of hydrogen cyanide gas by Greenawald, Lee A., Snyder, Jay L., Fry, Nicole L., Sailor, Michael J., Boss, Gerry R., Finklea, Harry O., Bell, Suzanne

“…•Monocyanocobinamide fixed on porous paper substrate binds gaseous HCN.•Paper substrate is positioned at end of fiber optic in diffuse reflectance…”
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Dye-Tethered Ruthenium Nitrosyls Containing Planar Dicarboxamide Tetradentate N4 Ligands: Effects of In-Plane Ligand Twist on NO Photolability by Fry, Nicole L, Heilman, Brandon J, Mascharak, Pradip K

“…To examine the steric effects of the in-plane ligands in dye-sensitized {RuNO}6 nitrosyls on their NO photolability, two new ligands, namely,…”
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Mechanism of NO Photodissociation in Photolabile Manganese–NO Complexes with Pentadentate N5 Ligands by Merkle, Anna C, Fry, Nicole L, Mascharak, Pradip K, Lehnert, Nicolai

“…The Mn-nitrosyl complexes [Mn­(PaPy3)­(NO)]­(ClO4) (1; PaPy3 – = N,N-bis­(2-pyridylmethyl)­amine-N-ethyl-2-pyridine-2-carboxamide) and…”
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Ruthenium Nitrosyls Derived from Tetradentate Ligands Containing Carboxamido-N and Phenolato-O Donors: Syntheses, Structures, Photolability, and Time Dependent Density Functional Theory Studies by Fry, Nicole L, Rose, Michael J, Rogow, David L, Nyitray, Crystal, Kaur, Manpreet, Mascharak, Pradip K

“…In order to examine the role(s) of designed ligands on the NO photolability of {Ru-NO}6 nitrosyls, a set of three nitrosyls with ligands containing two…”
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A light-activated NO donor attenuates anchorage independent growth of cancer cells: Important role of a cross talk between NO and other reactive oxygen species by Sen, Suvajit, Kawahara, Brian, Fry, Nicole L., Farias-Eisner, Robin, Zhang, Dalia, Mascharak, Pradip K., Chaudhuri, Gautam

“…•Light activated NO donation reduces anchorage independent growth in breast tumors.•Reduction in ROS is associated with anchorage independent growth.•NO up…”
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Facile Ligand Oxidation and Ring Nitration in Ruthenium Complexes Derived from a Ligand with Dicarboxamide-N and Phosphine-P Donors by Fry, Nicole L, Rose, Michael J, Nyitray, Crystal, Mascharak, Pradip K

“…The reaction of the tetradentate dicarboxamide ligand 1,2-bis-N-[2′(diphenylphosphanyl)benzoyl]diaminobenzene (dppbH2) with RuCl3 in DMF or ethanol results in…”
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Evidence of dexter energy transfer in NO photolability of dye-sensitized ruthenium nitrosyls by deBoer-Maggard, Tara R., Fry, Nicole L., Mascharak, Pradip K.

“…Introduction of a pyridinyloxy-linker between the dye FlEt (donor) and the ruthenium nitrosyl [(Me2bpb)Ru(NO)] unit (acceptor) causes a significant reduction…”
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Density functional theory studies on a designed photoactive {FeNO}6 nitrosyl and the corresponding photoinactive {FeNO}7 species: Insight into the origin of NO photolability by Fry, Nicole L., Zhao, Xiao P., Mascharak, Pradip K.

“…The {FeNO}6 nitrosyl derived from PaPy3H ligand releases NO upon exposure to low power visible light while the corresponding {FeNO}7 nitrosyl shows no NO…”
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