Search Results - "Fry, M. J."

Phosphoinositide 3-kinase signalling in breast cancer: how big a role might it play? by Fry, M J

“…Phosphoinositide 3-kinase (PI3K) was first identified as a lipid kinase activity associated with the products of viral oncogenes and with activated…”
Get full text

An assessment of the surface water resources of the Juba-Shabelle basin in southern Somalia by Houghton-Carr, H. A., Print, C. R., Fry, M. J., Gadain, H., Muchiri, P.

“…The water resources of the Juba and Shabelle rivers in southern Somalia are important for irrigation and food production, but are influenced by seasonal…”
Get full text

Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation by KAMALATI, T, JOLIN, H. E, FRY, M. J, CROMPTON, M. R

“…A high proportion of human breast cancers, in contrast with normal mammary tissue, express the intracellular tyrosine kinase BRK. BRK expression enhances the…”
Get full text

Phosphatidylinositol-3-OH kinase direct target of Ras by Rodriguez-Viciana, Pablo, Warne, Patricia H, Dhand, Ritu, Vanhaesebroeck, Bart, Gout, Ivan, Fry, Michael J, Waterfield, Michael D, Downward, Julian

“…Ras (p21ras) interacts directly with the catalytic subunit of phosphatidylinositol-3-OH kinase in a GTP-dependent manner through the Ras effector site. In…”
Get full text

Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C by Cook, D, Fry, M.J, Hughes, K, Sumathipala, R, Woodgett, J.R, Dale, T.C

“…The Drosophila gene product Wingless (Wg) is a secreted glycoprotein and a member of the Wnt gene family. Genetic analysis of Drosophila epidermal development…”
Get full text

Long-Term follow-up on restless legs syndrome patients treated with opioids by Walters, Arthur S., Winkelmann, Juliane, Trenkwalder, Claudia, Fry, June M., Kataria, Vandana, Wagner, Mary, Sharma, Rakesh, Hening, Wayne, Li, Liren

“…The medical records of 493 patients with restless legs syndrome (RLS) from three major centers were studied to determine the number and outcome of patients who…”
Get full text

Exogenous and endogenous market crashes as phase transitions in complex financial systems by Fry, J.M.

“…In this paper we provide a unifying framework for a set of seemingly disparate models for exogenous and endogenous shocks in complex financial systems. Markets…”
Get full text

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting by Schu, P.V. (University of California at San Diego), Takegawa, K, Fry, M.J, Stack, J.H, Waterfield, M.D, Emr, S.D

“…The VPS34 gene product (Vps34p) is required for protein sorting to the lysosome-like vacuole of the yeast Saccharomyces cerevisiae. Vps34p shares significant…”
Get full text

Interactions between SH2 domains and tyrosine-phosphorylated platelet-derived growth factor beta-receptor sequences: analysis of kinetic parameters by a novel biosensor-based approach by PANAYOTOU, G, GISH, G, END, P, TRUONG, O, GOUT, I, DHAND, R, FRY, M. J, HILES, I, PAWSON, T, WATERFIELD, M. D

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Structure, regulation and function of phosphoinositide 3-kinases by Fry, M J

Get more information

Treatment modalities for narcolepsy by FRY, J. M

“…Narcolepsy, a lifelong disorder, requires long-term management of symptoms. Interventions may be nonpharmacologic, such as lifestyle changes, and pharmacologic…”
Get full text

PI 3‐kinase is a dual specificity enzyme: autoregulation by an intrinsic protein‐serine kinase activity by Dhand, R., Hiles, I., Panayotou, G., Roche, S., Fry, M.J., Gout, I., Totty, N.F., Truong, O., Vicendo, P., Yonezawa, K.

“…Phosphatidylinositol 3‐kinase (PI 3‐kinase) has a regulatory 85 kDa adaptor subunit whose SH2 domains bind phosphotyrosine in specific recognition motifs, and…”
Get full text

'In the local context': Singaporean challenges to teaching games on practicum by McNeill, M.C., Fry, J.M., Wright, S.C., Tan, W.K.C., Tan, K.S.S., Schempp, P.G.

“…This is an investigation of 'situated learning' among Singaporean physical education student teachers (STs) (n=11) who used a games concept approach (GCA) on…”
Get full text

The indications for polysomnography and related procedures by CHESSON, A. L, FERBER, R. A, SANGAL, R. B, SCHMIDT-NOWARA, W, SHER, A, FRY, J. M, GRIGG-DAMBERGER, M, HARTSE, K. M, HURWITZ, T. D, JOHNSON, S, KADER, G. A, LITTNER, M, ROSEN, G

“…This paper is a review of the literature on the use of polysomnography in the diagnosis of sleep disorders in the adult. It is based on a search of MEDLINE…”
Get full text

An integrated water resource management tool for the Himalayan region by Rees, H.G., Holmes, M.G.R., Fry, M.J., Young, A.R., Pitson, D.G., Kansakar, S.R.

“…The Himalayan region of Nepal and northern India experiences hydrological extremes from monsoonal floods during July–September to periods of very low flows…”
Get full text

PI 3‐kinase: structural and functional analysis of intersubunit interactions by Dhand, R., Hara, K., Hiles, I., Bax, B., Gout, I., Panayotou, G., Fry, M.J., Yonezawa, K., Kasuga, M., Waterfield, M.D.

“…Phosphatidylinositol (PI) 3‐kinase has an 85 kDa subunit (p85 alpha) which mediates its association with activated protein tyrosine kinase receptors through…”
Get full text

A high-density immunoblotting methodology for quantification of total protein levels and phosphorylation modifications by Mazet, F., Dunster, J. L., Jones, C. I., Vaiyapuri, S., Tindall, M. J., Fry, M. J., Gibbins, J. M.

“…The components of many signaling pathways have been identified and there is now a need to conduct quantitative data-rich temporal experiments for systems…”
Get full text

Activated phosphoinositide 3-kinase associates with membrane skeleton in thrombin-exposed platelets by JIN ZHANG, FRY, M. J, WATERFIELD, M. D, JAKEN, S, LAN LIAO, FOX, J. E. B, RITTENHOUSE, S. E

“…Human platelets undergo a rapid, major reorganization of the cytoskeletal matrix upon exposure to thrombin, and accumulate 3-phosphorylated phosphoinositides…”
Get full text

Pediatricians and sleep disorders : training and practice by MINDELL, J. A, MOLINE, M. L, ZENDELL, S. M, BROWN, L. W, FRY, J. M

“…A series of studies were conducted to investigate pediatricians' training, knowledge, and practices regarding sleep and sleep disorders in children and…”
Get full text

Full polysomnography in the home by FRY, J. M, DIPHILLIPO, M. A, CURRAN, K, GOLDBERG, R, SINAN BARAN, A

“…To evaluate unattended full polysomnography (PSG) recorded in the home by the DigiTrace Home Sleep System (DHSS) and to assess the ability to acquire, store…”
Get full text