Search Results - "Frungieri, M. B"
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Ageing and inflammation in the male reproductive tract
Published in Andrologia (01-12-2018)“…Summary Ageing is usually characterised by a mild chronic proinflammatory state. Despite the tight association between both processes, the phenomenon has…”
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Evidence for an adaptation in ROS scavenging systems in human testicular peritubular cells from infertility patients
Published in International journal of andrology (01-12-2012)“…Summary Fibrosis, increased amounts of immune cells and expression of COX‐2 in the testes of infertility patients provide circumstantial evidence for a…”
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Human testicular mast cells contain tryptase: increased mast cell number and altered distribution in the testes of infertile men
Published in Fertility and sterility (01-08-2000)“…To determine whether human testicular mast cells contain the potent fibroblast growth factor tryptase and to examine changes in mast cell morphology and…”
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Aging in the Syrian hamster testis: Inflammatory-oxidative status and the impact of photoperiod
Published in Experimental gerontology (01-09-2019)“…Testicular aging is linked to histological, morphological and functional alterations. In the present study, we investigated whether aging affects the…”
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Mast cell–sperm interaction: evidence for tryptase and proteinase‐activated receptors in the regulation of sperm motility
Published in Human reproduction (Oxford) (01-12-2003)“…BACKGROUND: The detection of significant levels of tryptase in human seminal plasma and follicular fluid and of tryptase‐positive mast cells (MCs) in the wall…”
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Divergent effects of the major mast cell products histamine, tryptase and TNF-alpha on human fibroblast behaviour
Published in Cellular and molecular life sciences : CMLS (01-12-2005)“…Fibroblast proliferation is a key process in tissue remodeling and mast cells (MCs) are thought to play a crucial role. Having established that the three major…”
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Melatonin in testes of infertile men: evidence for anti‐proliferative and anti‐oxidant effects on local macrophage and mast cell populations
Published in Andrology (Oxford) (01-05-2014)“…Summary Melatonin acting through the hypothalamus and pituitary regulates testicular function. In addition, direct actions of melatonin at the testicular level…”
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The Ca2+-activated, large conductance K+-channel (BKCa) is a player in the LH/hCG signaling cascade in testicular Leydig cells
Published in Molecular and cellular endocrinology (10-03-2013)“…► The Ca2+-activated K+-channel (BKCa) is expressed by Leydig cells in adult hamster and human testis. ► BKCa is activated upon LH-receptor activation. ► It is…”
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Evidence for catecholaminergic, neuronlike cells in the adult human testis: changes associated with testicular pathologies
Published in Journal of andrology (01-05-1999)“…Neuronlike, catecholaminergic cells expressing tyrosine‐hydroxylase (TH) have recently been found in the testis of a nonhuman primate species, the rhesus…”
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The action of the mast cell product tryptase on cyclooxygenase-2 (COX2) and subsequent fibroblast proliferation involves activation of the extracellular signal-regulated kinase isoforms 1 and 2 (erk1/2)
Published in Cellular signalling (01-04-2005)“…The mast cell product tryptase, via protease-activated receptor 2 (PAR2), induces cyclooxygenase-2 (COX2) and 15-deoxy-prostaglandin J2 (15d-PGJ2) synthesis…”
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Influence of photoinhibition on GABA and glutamic acid levels, and on glutamate decarboxylase activity in the testis and epididymis of the golden hamster
Published in International journal of andrology (01-06-1996)“…Gamma-aminobutyric acid (GABA) is found in the gonads and accessory reproductive organs, and a direct effect on steroidogenesis and sperm viability and…”
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Evidence for a GABAergic system in rodent and human testis: local GABA production and GABA receptors
Published in Neuroendocrinology (01-05-2003)“…The major neurotransmitter of the central nervous system, gamma-aminobutyric acid (GABA), exerts its actions through GABA(A), GABA(B) and GABA(C) receptors…”
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Influence of age and photoperiod on steroidogenic function of the testis in the golden hamster
Published in International journal of andrology (01-08-1999)“…The golden (Syrian) hamster is a seasonal breeder, and exposure of adult animals to short days results in severe gonadal regression with morphological features…”
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Testicular gamma-aminobutyric acid and circulating androgens in Syrian and Djungarian hamsters during sexual development
Published in International journal of andrology (01-06-1996)“…Several factors, besides luteinizing hormone (LH), participate in the modulation of testicular function. A number of neurotransmitters are reported to be…”
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Interactions between testicular serotoninergic, catecholaminergic, and corticotropin-releasing hormone systems modulating cAMP and testosterone production in the golden hamster
Published in Neuroendocrinology (01-07-2002)“…We previously reported the presence of serotonin (5-HT) in testes from golden hamster, a photoperiodic species which is a useful model for the study of states…”
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Polyamine levels in testes and seminal vesicles from adult golden hamsters during gonadal regression-recrudescence
Published in Journal of andrology (01-11-1996)“…The exposure of golden hamsters to short days results in early regression of the reproductive organs and subsequent spontaneous recrudescence characterized by…”
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Insights into GABA receptor signalling in TM3 Leydig cells
Published in Neuroendocrinology (01-01-2005)“…Gamma-aminobutyric acid (GABA) is an emerging signalling molecule in endocrine organs, since it is produced by endocrine cells and acts via GABA(A) receptors…”
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Neuronal elements in the testis of the rhesus monkey: ontogeny, characterization and relationship to testicular cells
Published in Neuroendocrinology (01-01-2000)“…Intrinsic neuron-like cells expressing the catecholamine-biosynthetic enzyme tyrosine hydroxylase (TH) were recently identified in the testis of the…”
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Serotonin in golden hamster testes: testicular levels, immunolocalization and role during sexual development and photoperiodic regression-recrudescence transition
Published in Neuroendocrinology (01-04-1999)“…Serotonin (5-HT) is found in the gonads and accessory reproductive organs of several species. The golden (Syrian) hamster is a seasonal breeder. Exposure of…”
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