Search Results - "Fruchart, C"

FDG-PET–driven consolidation strategy in diffuse large B-cell lymphoma: final results of a randomized phase 2 study by Casasnovas, R.-O., Ysebaert, L., Thieblemont, C., Bachy, E., Feugier, P., Delmer, A., Tricot, S., Gabarre, J., Andre, M., Fruchart, C., Mounier, N., Delarue, R., Meignan, M., Berriolo-Riedinger, A., Bardet, S., Emile, J.-F., Jais, J.-P., Haioun, C., Tilly, H., Morschhauser, F.

“…Dose-dense induction and up-front consolidation with autologous stem cell transplantation (ASCT) remain controversial issues when treating patients with…”
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Peroxisome proliferator-activated receptors in inflammation control by Delerive, P, Fruchart, JC, Staels, B

“…Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the nuclear receptor superfamily. PPARalpha is…”
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Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation by Chinetti, G, Fruchart, J C, Staels, B

“…Peroxisome proliferator-activated (PPARs) are ligand-activated transcription factors belonging to the nuclear receptor family. PPARs function as regulators of…”
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Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis by BARBIER, O, PINEDA TORRA, I, DUGUAY, Y, BLANQUART, C, FRUCHART, J.-C, GLINEUR, C, STAELS, B

“…Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors activated by fatty acids and derivatives. Although PPARalpha mediates the…”
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Deletion of the 1p32 region is a major independent prognostic factor in young patients with myeloma: the IFM experience on 1195 patients by Hebraud, B, Leleu, X, Lauwers-Cances, V, Roussel, M, Caillot, D, Marit, G, Karlin, L, Hulin, C, Gentil, C, Guilhot, F, Garderet, L, Lamy, T, Brechignac, S, Pegourie, B, Jaubert, J, Dib, M, Stoppa, A-M, Sebban, C, Fohrer, C, Fontan, J, Fruchart, C, Macro, M, Orsini-Piocelle, F, Lepeu, G, Sohn, C, Corre, J, Facon, T, Moreau, P, Attal, M, Avet-Loiseau, H

“…Deletions of the 1p region appear as a pejorative prognostic factor in multiple myeloma patients (especially 1p22 and 1p32 deletions) but there is a lack of…”
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An Apolipoprotein Influencing Triglycerides in Humans and Mice Revealed by Comparative Sequencing by Pennacchio, Len A., Olivier, Michael, Hubacek, Jaroslav A., Cohen, Jonathan C., Cox, David R., Fruchart, Jean-Charles, Krauss, Ronald M., Rubin, Edward M.

“…Comparison of genomic DNA sequences from human and mouse revealed a new apolipoprotein (APO) gene (APOAV) located proximal to the well-characterized…”
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Real-world data for marginal zone lymphoma patients in the French REALYSA cohort: The REALMA study by Bommier, C, Donzel, M, Rossi, C, Fornecker, L M, Bijou, F, Chauchet, A, Lebras, L, Ysabaert, L, Haioun, C, Bouabdallah, K, Gastinne, T, Morineau, N, Amorim, S, Jardin, F, Abraham, J, Lamy de la Chapelle, T, Gressin, R, Fouillet, L, Fruchart, C, Olivier, G, Morschhauser, F, Cherblanc, F, Belot, A, Le Guyader, S, Monnereau, A, Ghesquieres, H, Thieblemont, C

“…Marginal Zone Lymphoma (MZL) comprises three subtypes: extranodal MZL (EMZL), splenic MZL (SMZL) and nodal MZL (NMZL). Since clinical trials have limited…”
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Peroxisome Proliferator-Activated Receptor α Reduces Cholesterol Esterification in Macrophages by Chinetti, G, Lestavel, S, Fruchart, J.-C, Clavey, V, Staels, B

“…ABSTRACT—Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor activated by fatty acid derivatives and hypolipidemic drugs of the fibrate…”
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REALMA: Subset of patients with Marginal Zone Lymphomas from the French nationwide REALYSA real‐world prospective cohort by Bommier, C., Donzel, M., Rossi, C., Fornecker, L., Bijou, F., Chauchet, A., Lebras, L., Ysebaert, L., Haioun, C., Bouabdallah, K., Morineau, N., Gastinne, T., Amorim, S., Jardin, F., Abraham, J., Lamy de la Chapelle, T., Gressin, R., Fouillet, L., Fruchart, C., Morschhauser, F., Olivier, G., Cherblanc, F., Belot, A., Le Guyader, S., Monnereau, A., Ghesquières, H., Thieblemont, C.

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Alteration of the in vivo nicotinic receptor density in ADNFLE patients: a PET study by Picard, F., Bruel, D., Servent, D., Saba, W., Fruchart-Gaillard, C., Schöllhorn-Peyronneau, M.-A., Roumenov, D., Brodtkorb, E., Zuberi, S., Gambardella, A., Steinborn, B., Hufnagel, A., Valette, H., Bottlaender, M.

“…Nicotinic acetylcholine receptors (nAChRs) are involved in a familial form of frontal lobe epilepsy, autosomal dominant nocturnal frontal lobe epilepsy…”
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PI3K inhibition and modulation of immune and tumor microenvironment markers by copanlisib in patients with non-Hodgkin's lymphoma or advanced solid tumors by Awada, A.H., Morschhauser, F., Machiels, J.-P., Salles, G., Rottey, S., Rule, S., Cunningham, D., Peyrade, F., Fruchart, C., Arkenau, H.-T., Genvresse, I., Koechert, K., Cisternas, G., Granvil, C., Pena, C., Liu, L.

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LONG‐TERM OUTCOMES OF ELDERLY PATIENTS TREATED WITH FRONTLINE R‐CHOP: UPDATE OF THE LNH03‐6B TRIAL by Camus, V., Belot, Aurél., Oberic, L., Sibon, D., Ghesquières, H., Thieblemont, C., Fruchart, C., Casasnovas, O., Michot, Jean‐M., Molina, T. J., Bosly, A., Joubert, Clém., Haioun, C., Delarue, R., Tilly, H.

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Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARα, PPARγ, and LXR by Chinetti, G, Zawadski, C, Fruchart, J.C, Staels, B

“…Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors expressed in macrophages where they control cholesterol homeostasis and inflammation…”
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Long-term follow-up of high-dose treatment with autologous haematopoietic progenitor cell support in 693 patients with follicular lymphoma: an EBMT registry study by MONTOTO, S, CANALS, C, SLAVIN, S, CONDE, E, FRUCHART, C, FERRANT, A, LEBLOND, V, TILLY, H, LISTER, T. A, GOLDSTONE, A. H, ROHATINER, A. Z. S, TAJHIPOUR, G, SUREDA, A, SCHMITZ, N, GISSELBRECHT, C, FOUILLARD, L, MILPIED, N, HAIOUN, C

“…To evaluate the outcome of a large series of patients who received high-dose treatment (HDT) for follicular lymphoma (FL), 693 patients undergoing HDT…”
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An update on the mechanisms of action of the peroxisome proliferator-activated receptors (PPARs) and their roles in inflammation and cancer by Gelman, L, Fruchart, J C, Auwerx, J

“…Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors and have been initially described as molecular targets for compounds which induce…”
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Hypodiploidy is a major prognostic factor in multiple myeloma by Smadja, Nicole Véronique, Bastard, Christian, Brigaudeau, Christophe, Leroux, Dominique, Fruchart, Christophe

“…Conventional karyotypes performed before any treatment in 208 patients with multiple myeloma were reviewed by the Groupe Français de Cytogénétique…”
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Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators by Staels, Bart, Koenig, Wolfgang, Habib, Aïda, Merval, Régine, Lebret, Marilyne, Torra, Inés Pineda, Delerive, Philippe, Fadel, Abdessamad, Chinetti, Giulia, Fruchart, Jean-Charles, Najib, Jamila, Maclouf, Jacques, Tedgui, Alain

“…Peroxisome proliferator-activated receptors (PPARs) are key players in lipid and glucose metabolism and are implicated in metabolic disorders predisposing to…”
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Impact of the use of autologous stem cell transplantation at first relapse both in naïve and previously rituximab exposed follicular lymphoma patients treated in the GELA/GOELAMS FL2000 study by LE GOUILL, Steven, DE GUIBERT, Sophie, FRUCHART, Christophe, DECONINCK, Eric, FITOUSSI, Olivier, GASTAUD, Lauris, DELWAIL, Vincent, GABARRE, Jean, GRESSIN, Rémy, BLANC, Michel, FOUSSARD, Charles, SALLES, Gilles, PLANCHE, Lucie, BRICE, Pauline, DUPUIS, Jehan, CARTRON, Guillaume, VAN HOOF, Achiel, CASASNOVAS, Olivier, GYAN, Emmanuel, TILLY, Hervé

“…We analyzed detailed characteristics and salvage treatment in 175 follicular lymphoma patients from the FL2000 study who were in progression after first-line…”
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Peroxisome proliferator-activated receptors and inflammation: from basic science to clinical applications by Chinetti, G, Fruchart, J.C, Staels, B

“…Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor family. After activation by specific ligands, they regulate the…”
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Lymphoma occurring in patients over 90 years of age: characteristics, outcomes, and prognostic factors. A retrospective analysis of 234 cases from the LYSA by Trebouet, A., Marchand, T., Lemal, R., Gyan, E., Broussais-Guillaumot, F., Guillermin, Y., Monjanel, H., Salles, G., Le Gouill, S., Godmer, P., Fruchart, C., Damaj, G., Feugier, P., Thieblemont, C., Maynadié, M., Monnereau, A., Troussard, X., Rossille, D., Lamy, T., Houot, R.

“…Lymphoma occurring in patients aged 90 or older is not uncommon, and its incidence is expected to increase over time. Management of these patients is difficult…”
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