Search Results - "Frtús, Adam"
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Analyzing the mechanisms of iron oxide nanoparticles interactions with cells: A road from failure to success in clinical applications
Published in Journal of controlled release (10-12-2020)“…Iron oxide nanoparticles (IONPs) were the first generation of nanomaterials that reached real clinic use. Particularly, several IONPs-based magnetic resonance…”
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Lysosomal nanotoxicity: Impact of nanomedicines on lysosomal function
Published in Advanced drug delivery reviews (01-06-2023)“…[Display omitted] •A critical review on adverse drug reactions of current nanomedicines.•Overview of literature on how nanoparticles bias lysosomal…”
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Protein Corona Inhibits Endosomal Escape of Functionalized DNA Nanostructures in Living Cells
Published in ACS applied materials & interfaces (06-10-2021)“…DNA nanostructures (DNs) can be designed in a controlled and programmable manner, and these structures are increasingly used in a variety of biomedical…”
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Critical Analysis of Non-Thermal Plasma-Driven Modulation of Immune Cells from Clinical Perspective
Published in International journal of molecular sciences (28-08-2020)“…The emerged field of non-thermal plasma (NTP) shows great potential in the alteration of cell redox status, which can be utilized as a promising therapeutic…”
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Sensitivity of endogenous autofluorescence in HeLa cells to the application of external magnetic fields
Published in Scientific reports (04-07-2023)“…Dramatically increased levels of electromagnetic radiation in the environment have raised concerns over the potential health hazards of electromagnetic fields…”
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The interactions between DNA nanostructures and cells: A critical overview from a cell biology perspective
Published in Acta biomaterialia (01-07-2022)“…DNA nanotechnology has yielded remarkable advances in composite materials with diverse applications in biomedicine. The specificity and predictability of…”
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Mechanical Regulation of Mitochondrial Dynamics and Function in a 3D-Engineered Liver Tumor Microenvironment
Published in ACS biomaterials science & engineering (08-05-2023)“…It has become evident that physical stimuli of the cellular microenvironment transmit mechanical cues regulating key cellular functions, such as proliferation,…”
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Iron Oxide Nanoparticle-Induced Autophagic Flux Is Regulated by Interplay between p53-mTOR Axis and Bcl-2 Signaling in Hepatic Cells
Published in Cells (Basel, Switzerland) (18-04-2020)“…Iron oxide-based nanoparticles have been repeatedly shown to affect lysosomal-mediated signaling. Recently, nanoparticles have demonstrated an ability to…”
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Detection of mitochondrial haplogroups in a small avar‐slavic population from the eigth–ninth century AD
Published in American journal of physical anthropology (01-03-2018)“…Objectives In the sixth century AD, Avars came to Central Europe from middle Eurasian steppes and founded a strong Empire called the Avar Khagante (568–799/803…”
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Hepatic Tumor Cell Morphology Plasticity under Physical Constraints in 3D Cultures Driven by YAP-mTOR Axis
Published in Pharmaceuticals (Basel, Switzerland) (28-11-2020)“…Recent studies undoubtedly show that the mammalian target of rapamycin (mTOR) and the Hippo-Yes-associated protein 1 (YAP) pathways are important mediators of…”
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Serious chronic disease of the cervical spine and trauma in a young female from the middle ages (Czech Republic)
Published in International journal of paleopathology (01-03-2019)“…The skeletal remains of the young female (20-24 years) from Grave JP/106, discovered in the Southern Suburb of the Břeclav - Pohansko Stronghold (Early Middle…”
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