Search Results - "Frostig, Ron D"
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Astrocyte-neuron lactate shuttle plays a pivotal role in sensory-based neuroprotection in a rat model of permanent middle cerebral artery occlusion
Published in Scientific reports (07-08-2023)“…We have previously demonstrated protection from impending cortical ischemic stroke is achievable by sensory stimulation of the ischemic area in an adult rat…”
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Testing the effects of sensory stimulation as a collateral-based therapeutic for ischemic stroke in C57BL/6J and CD1 mouse strains
Published in PloS one (13-09-2017)“…Utilizing a rat model of ischemic stroke, we have previously shown that sensory stimulation can completely protect rats from impending ischemic damage of…”
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Sensory stimulation-based protection from impending stroke following MCA occlusion is correlated with desynchronization of widespread spontaneous local field potentials
Published in Scientific reports (02-02-2022)“…In a rat model of ischemic stroke by permanent occlusion of the medial cerebral artery (pMCAo), we have demonstrated using continuous recordings by…”
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Hypertension prevents a sensory stimulation-based collateral therapeutic from protecting the cortex from impending ischemic stroke damage in a spontaneously hypersensitive rat model
Published in PloS one (23-10-2018)“…Assessing potential stroke treatments in the presence of risk factors can improve screening of treatments prior to clinical trials and is important in testing…”
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Rapid development of strong, persistent, spatiotemporally extensive cortical synchrony and underlying oscillations following acute MCA focal ischemia
Published in Scientific reports (08-12-2020)“…Stroke is a leading cause of death and the leading cause of long-term disability, but its electrophysiological basis is poorly understood. Characterizing acute…”
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Author Correction: Rapid development of strong, persistent, spatiotemporally extensive cortical synchrony and underlying oscillations following acute MCA focal ischemia
Published in Scientific reports (24-03-2021)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Complete protection from impending stroke following permanent middle cerebral artery occlusion in awake, behaving rats
Published in The European journal of neuroscience (01-11-2014)“…Using a rodent model of ischemic stroke [permanent middle cerebral artery occlusion (pMCAO)], our laboratory has previously demonstrated that sensory‐evoked…”
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Mild sensory stimulation completely protects the adult rodent cortex from ischemic stroke
Published in PloS one (23-06-2010)“…Despite progress in reducing ischemic stroke damage, complete protection remains elusive. Here we demonstrate that, after permanent occlusion of a major…”
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Unimodal primary sensory cortices are directly connected by long-range horizontal projections in the rat sensory cortex
Published in Frontiers in neuroanatomy (24-09-2014)“…Research based on functional imaging and neuronal recordings in the barrel cortex subdivision of primary somatosensory cortex (SI) of the adult rat has…”
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Long-Range, Border-Crossing, Horizontal Axon Radiations Are a Common Feature of Rat Neocortical Regions That Differ in Cytoarchitecture
Published in Frontiers in neuroanatomy (21-06-2018)“…Employing wide-field optical imaging techniques supported by electrophysiological recordings, previous studies have demonstrated that stimulation of a…”
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Large-Scale Organization of Rat Sensorimotor Cortex Based on a Motif of Large Activation Spreads
Published in The Journal of neuroscience (03-12-2008)“…Parcellation according to function (e.g., visual, somatosensory, auditory, motor) is considered a fundamental property of sensorimotor cortical organization,…”
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Fully distributed absolute blood flow velocity measurement for middle cerebral arteries using Doppler optical coherence tomography
Published in Biomedical optics express (01-02-2016)“…Doppler optical coherence tomography (DOCT) is considered one of the most promising functional imaging modalities for neuro biology research and has…”
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Spatiotemporal dynamics of pial collateral blood flow following permanent middle cerebral artery occlusion in a rat model of sensory-based protection: a Doppler optical coherence tomography study
Published in Neurophotonics (Print) (01-10-2019)“…There is a growing recognition regarding the importance of pial collateral flow in the protection from impending ischemic stroke both in preclinical and…”
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Early stimulation treatment provides complete sensory-induced protection from ischemic stroke under isoflurane anesthesia
Published in The European journal of neuroscience (01-08-2013)“…Using a rodent model of ischemia [permanent middle cerebral artery occlusion (pMCAO)], previous studies demonstrated that whisker stimulation treatment…”
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Imaging cortical absorption, scattering, and hemodynamic response during ischemic stroke using spatially modulated near-infrared illumination
Published in Journal of Biomedical Optics (2009)“…We describe a technique that uses spatially modulated near-infrared (NIR) illumination to detect and map changes in both optical properties (absorption and…”
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Naturalistic experience transforms sensory maps in the adult cortex of caged animals
Published in Nature (06-05-2004)“…Much of what is known about the functional organization and plasticity of adult sensory cortex is derived from animals housed in standard laboratory cages…”
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Break point detection for functional covariance
Published in Scandinavian journal of statistics (01-06-2023)“…Many neuroscience experiments record sequential trajectories where each trajectory consists of oscillations and fluctuations around zero. Such trajectories can…”
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Emergence of spatiotemporal invariance in large neuronal ensembles in rat barrel cortex
Published in Frontiers in neural circuits (08-07-2015)“…Invariant sensory coding is the robust coding of some sensory information (e.g., stimulus type) despite major changes in other sensory parameters (e.g.,…”
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Variation pattern classification of functional data
Published in Canadian journal of statistics (01-12-2023)“…Abstract A new classification method for functional data is proposed in this article. This work is motivated by the need to identify features that discriminate…”
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Regularized matrix data clustering and its application to image analysis
Published in Biometrics (01-09-2021)“…We propose a novel regularized mixture model for clustering matrix‐valued data. The proposed method assumes a separable covariance structure for each cluster…”
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