Search Results - "Frontiers in endocrinology (Lausanne)"

Update on Fundamental Mechanisms of Thyroid Cancer by Prete, Alessandro, Borges de Souza, Patricia, Censi, Simona, Muzza, Marina, Nucci, Nicole, Sponziello, Marialuisa

“…The incidence of thyroid cancer (TC) has increased worldwide over the past four decades. TC is divided into three main histological types: differentiated…”
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Vitamin D Binding Protein, Total and Free Vitamin D Levels in Different Physiological and Pathophysiological Conditions by Bikle, Daniel David, Schwartz, Janice

“…This review focuses on the biologic importance of the vitamin D binding protein (DBP) with emphasis on its regulation of total and free vitamin D metabolite…”
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COVID-19 and Diabetes: Understanding the Interrelationship and Risks for a Severe Course by Landstra, Cyril P, de Koning, Eelco J P

“…The relationship between COVID-19 and diabetes mellitus is complicated and bidirectional. On the one hand, diabetes mellitus is considered one of the most…”
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Long-Term Effects of a Novel Continuous Remote Care Intervention Including Nutritional Ketosis for the Management of Type 2 Diabetes: A 2-Year Non-randomized Clinical Trial by Athinarayanan, Shaminie J, Adams, Rebecca N, Hallberg, Sarah J, McKenzie, Amy L, Bhanpuri, Nasir H, Campbell, Wayne W, Volek, Jeff S, Phinney, Stephen D, McCarter, James P

“…Studies on long-term sustainability of low-carbohydrate approaches to treat diabetes are limited. We previously reported the effectiveness of a novel…”
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Unhealthy Lifestyle and Gut Dysbiosis: A Better Understanding of the Effects of Poor Diet and Nicotine on the Intestinal Microbiome by Martinez, Jason E, Kahana, Doron D, Ghuman, Simran, Wilson, Haley P, Wilson, Julian, Kim, Samuel C J, Lagishetty, Venu, Jacobs, Jonathan P, Sinha-Hikim, Amiya P, Friedman, Theodore C

“…The study of the intestinal or gut microbiome is a newer field that is rapidly gaining attention. Bidirectional communication between gut microbes and the host…”
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Molecular Mechanisms of Action of FSH by Casarini, Livio, Crépieux, Pascale

“…The glycoprotein follicle-stimulating hormone (FSH) acts on gonadal target cells, hence regulating gametogenesis. The transduction of the hormone-induced…”
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Endocrine Resistance in Hormone Receptor Positive Breast Cancer-From Mechanism to Therapy by Rani, Aradhana, Stebbing, Justin, Giamas, Georgios, Murphy, John

“…The importance and role of the estrogen receptor (ER) pathway has been well-documented in both breast cancer (BC) development and progression. The treatment of…”
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ANRIL : A lncRNA at the CDKN2A/B Locus With Roles in Cancer and Metabolic Disease by Kong, Yahui, Hsieh, Chih-Heng, Alonso, Laura C

“…The genomic locus is associated with risk of human cancers and metabolic disease. Although the locus contains several important protein-coding genes, studies…”
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Genetics and Epigenetics: New Insight on Gestational Diabetes Mellitus by Dalfrà, Maria Grazia, Burlina, Silvia, Del Vescovo, Gloria Giovanna, Lapolla, Annunziata

“…Gestational diabetes mellitus (GDM) is the most common metabolic complication of pregnancy, with a prevalence that has increased significantly in the last…”
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The p53 Tumor Suppressor in the Control of Metabolism and Ferroptosis by Gnanapradeepan, Keerthana, Basu, Subhasree, Barnoud, Thibaut, Budina-Kolomets, Anna, Kung, Che-Pei, Murphy, Maureen E

“…The p53 tumor suppressor continues to be distinguished as the most frequently mutated gene in human cancer. It is widely believed that the ability of p53 to…”
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Obesity and Weight Gain in Pregnancy and Postpartum: an Evidence Review of Lifestyle Interventions to Inform Maternal and Child Health Policies by Farpour-Lambert, Nathalie J, Ells, Louisa J, Martinez de Tejada, Begoña, Scott, Courtney

“…Maternal obesity, excessive gestational weight gain (GWG) and post-partum weight retention (PPWR) constitute new public health challenges, due to the…”
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The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication by Silva, Ygor Parladore, Bernardi, Andressa, Frozza, Rudimar Luiz

“…A substantial body of evidence supports that the gut microbiota plays a pivotal role in the regulation of metabolic, endocrine and immune functions. In recent…”
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Insulin in the brain: its pathophysiological implications for States related with central insulin resistance, type 2 diabetes and Alzheimer's disease by Blázquez, Enrique, Velázquez, Esther, Hurtado-Carneiro, Verónica, Ruiz-Albusac, Juan Miguel

“…Although the brain has been considered an insulin-insensitive organ, recent reports on the location of insulin and its receptors in the brain have introduced…”
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Obesity: Epidemiology, Pathophysiology, and Therapeutics by Lin, Xihua, Li, Hong

“…Obesity is a complex multifactorial disease that accumulated excess body fat leads to negative effects on health. Obesity continues to accelerate resulting in…”
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Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation by O'Brien, Jacob, Hayder, Heyam, Zayed, Yara, Peng, Chun

“…MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating gene expression. The majority of miRNAs are transcribed from DNA…”
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Prevalence of Overweight and Obesity in People With Severe Mental Illness: Systematic Review and Meta-Analysis by Afzal, Medhia, Siddiqi, Najma, Ahmad, Bilal, Afsheen, Nida, Aslam, Faiza, Ali, Ayaz, Ayesha, Rubab, Bryant, Maria, Holt, Richard, Khalid, Humaira, Ishaq, Kousar, Koly, Kamrun Nahar, Rajan, Sukanya, Saba, Jobaida, Tirbhowan, Nilesh, Zavala, Gerardo A

“…1) To determine the pooled prevalence of overweight and obesity in people with severe mental illness (SMI), overall and by type of SMI, geographical region,…”
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Leptin and Obesity: Role and Clinical Implication by Obradovic, Milan, Sudar-Milovanovic, Emina, Soskic, Sanja, Essack, Magbubah, Arya, Swati, Stewart, Alan J, Gojobori, Takashi, Isenovic, Esma R

“…The peptide hormone leptin regulates food intake, body mass, and reproductive function and plays a role in fetal growth, proinflammatory immune responses,…”
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Immune Cell Confrontation in the Papillary Thyroid Carcinoma Microenvironment by Xie, Zhenyu, Li, Xin, He, Yuzhen, Wu, Song, Wang, Shiyue, Sun, Jianjian, He, Yuchen, Lun, Yu, Zhang, Jian

“…Papillary thyroid cancer has been associated with chronic inflammation. A systematic understanding of immune cell infiltration in PTC is essential for…”
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Prognostic Impact of Hyponatremia and Hypernatremia in COVID-19 Pneumonia. A HOPE-COVID-19 (Health Outcome Predictive Evaluation for COVID-19) Registry Analysis by Ruiz-Sánchez, Jorge Gabriel, Núñez-Gil, Ivan J, Cuesta, Martin, Rubio, Miguel A, Maroun-Eid, Charbel, Arroyo-Espliguero, Ramón, Romero, Rodolfo, Becerra-Muñoz, Victor Manuel, Uribarri, Aitor, Feltes, Gisela, Trabattoni, Daniela, Molina, María, García Aguado, Marcos, Pepe, Martino, Cerrato, Enrico, Alfonso, Emilio, Castro Mejía, Alex Fernando, Roubin, Sergio Raposeiras, Buzón, Luis, Bondia, Elvira, Marin, Francisco, López Pais, Javier, Abumayyaleh, Mohammad, D'Ascenzo, Fabrizio, Rondano, Elisa, Huang, Jia, Fernandez-Perez, Cristina, Macaya, Carlos, de Miguel Novoa, Paz, Calle-Pascual, Alfonso L, Estrada Perez, Vicente, Runkle, Isabelle

“…Dysnatremia is associated with increased mortality in patients with community-acquired pneumonia. SARS-COV2 (Severe-acute-respiratory syndrome caused by…”
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The Bones of Children With Obesity by Fintini, Danilo, Cianfarani, Stefano, Cofini, Marta, Andreoletti, Angela, Ubertini, Grazia Maria, Cappa, Marco, Manco, Melania

“…Excess adiposity in childhood may affect bone development, ultimately leading to bone frailty. Previous reports showing an increased rate of extremity…”
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