Search Results - "Frontera, Vincent"

Microhomologies are prevalent at Cas9-induced larger deletions by Owens, Dominic D G, Caulder, Adam, Frontera, Vincent, Harman, Joe R, Allan, Alasdair J, Bucakci, Akin, Greder, Lucas, Codner, Gemma F, Hublitz, Philip, McHugh, Peter J, Teboul, Lydia, de Bruijn, Marella F T R

“…Abstract The CRISPR system is widely used in genome editing for biomedical research. Here, using either dual paired Cas9D10A nickases or paired Cas9 nuclease…”
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The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition by Azzoni, Emanuele, Frontera, Vincent, Anselmi, Giorgio, Rode, Christina, James, Chela, Deltcheva, Elitza M., Demian, Atanasiu S., Brown, John, Barone, Cristiana, Patelli, Arianna, Harman, Joe R., Nicholls, Matthew, Conway, Simon J., Morrissey, Edward, Jacobsen, Sten Eirik W., Sparrow, Duncan B., Harris, Adrian L., Enver, Tariq, de Bruijn, Marella F.T.R.

“…Hematopoietic stem cells (HSCs) emerge during development from the vascular wall of the main embryonic arteries. The onset of circulation triggers several…”
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Function of Jam‐B/Jam‐C Interaction in Homing and Mobilization of Human and Mouse Hematopoietic Stem and Progenitor Cells by Arcangeli, Marie‐Laure, Bardin, Florence, Frontera, Vincent, Bidaut, Ghislain, Obrados, Elodie, Adams, Ralf H., Chabannon, Christian, Aurrand‐Lions, Michel

“…The junctional adhesion molecules Jam‐b and Jam‐c interact together at interendothelial junctions and have been involved in the regulation of immune response,…”
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The Junctional Adhesion Molecule-B regulates JAM-C-dependent melanoma cell metastasis by Arcangeli, Marie-Laure, Frontera, Vincent, Bardin, Florence, Thomassin, Jeanne, Chetaille, Bruno, Adams, Susanne, Adams, Ralf H., Aurrand-Lions, Michel

“…► JAM-B is highly expressed on Lung Microvascular Endothelial Cells. ► JAM-B/JAM-C interaction mediates melanoma cell adhesion to endothelial cells in vitro. ►…”
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JAM-B regulates maintenance of hematopoietic stem cells in the bone marrow by Arcangeli, Marie-Laure, Frontera, Vincent, Bardin, Florence, Obrados, Elodie, Adams, Susanne, Chabannon, Christian, Schiff, Claudine, Mancini, Stephane. J.C., Adams, Ralf H., Aurrand-Lions, Michel

“…In adult mammals, hematopoietic stem cells (HSCs) reside in the bone marrow (BM) and are maintained in a quiescent and undifferentiated state through adhesive…”
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3008 – HARNESSING RUNX1 ENHANCER-REPORTER MODELS TO ELUCIDATE THE SPECIFICATION OF HSC IN THE MOUSE EMBRYO by Anselmi, Giorgio, Rode, Christina, Frontera, Vincent, Jarratt, Andrew, Harman, Joe, de Bruijn, Marella

“…During embryonic development, hematopoietic stem and progenitor cells (HSPCs) originate in asynchronous waves from hemogenic endothelium (HE) via a tightly…”
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Circulating plasmablasts and high level of BAFF are hallmarks of minimal change nephrotic syndrome in adults by Oniszczuk, Julie, Beldi-Ferchiou, Asma, Audureau, Etienne, Azzaoui, Imane, Molinier-Frenkel, Valérie, Frontera, Vincent, Karras, Alexandre, Moktefi, Anissa, Pillebout, Evangeline, Zaidan, Mohamad, El Karoui, Khalil, Delfau-Larue, Marie-Hélène, Hénique, Carole, Ollero, Mario, Sahali, Dil, Mahévas, Matthieu, Audard, Vincent

“…Abstract Background The recent success achieved with the use of B cell-depleting agents in some patients with minimal change nephrotic syndrome (MCNS) suggests…”
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2018 – RECONSTRUCTION OF A DORSAL AORTA HEMOGENIC ENDOTHELIUM GENE REGULATORY NETWORK IDENTIFIES A RUNX1:IKZF1:NOTCH FEED-FORWARD LOOP by Harman, Joe, Greder, Lucas, Swiers, Gemma, Owens, Dominic, Suciu, Maria, Downes, Damien, Telenius, Jelena, Frontera, Vincent, Antoniou, Stella, Repapi, Emmanouela, Azzoni, Emanuele, de Bruijn, Marella

“…In vertebrate embryos, hematopoietic stem cells (HSCs) are generated from a subset of the aortic endothelium, the hemogenic endothelium, via a process called…”
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2003 - The Mouse Hematopoietic Stem Cell Lineage Fails to Develop Beyond the Pro-HSC Stage in the Absence of Blood Flow by Azzoni, Emanuele, Frontera, Vincent, Harman, Joe, Jacobsen, Sten Eirik, De Bruijn, Marella

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Kit ligand has a critical role in mouse yolk sac and aorta–gonad–mesonephros hematopoiesis by Azzoni, Emanuele, Frontera, Vincent, McGrath, Kathleen E, Harman, Joe, Carrelha, Joana, Nerlov, Claus, Palis, James, Jacobsen, Sten Eirik W, de Bruijn, Marella FTR

“…Few studies report on the in vivo requirement for hematopoietic niche factors in the mammalian embryo. Here, we comprehensively analyze the requirement for Kit…”
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3129 - Dynamic Regulation of Runx1 at the Onset of Definitive Hematopoiesis by Owens, Dominic, Rode, Christina, Frontera, Vincent, Greder, Lucas, Jarratt, Andrew, Harman, Joe, Downes, Damien, Hughes, Jim, de Bruijn, Marella

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Dynamic Regulation of Runx1 at the Onset of Definitive Hematopoiesis by Owens, Dominic, Rode, Christina, Frontera, Vincent, Greder, Lucas, Jarratt, Andrew, Harman, Joe, Downes, Damien, Hughes, Jim, de Bruijn, Marella

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CMIP is a negative regulator of T cell signaling by Oniszczuk, Julie, Sendeyo, Kelhia, Chhuon, Cerina, Savas, Berkan, Cogné, Etienne, Vachin, Pauline, Henique, Carole, Guerrera, Ida Chiara, Astarita, Giuseppe, Frontera, Vincent, Pawlak, Andre, Audard, Vincent, Sahali, Dil, Ollero, Mario

“…Upon their interaction with cognate antigen, T cells integrate different extracellular and intracellular signals involving basal and induced protein–protein…”
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The Mouse Hematopoietic Stem Cell Lineage Fails to Develop Beyond the Pro-HSC Stage in the Absence of Blood Flow by Azzoni, Emanuele, Frontera, Vincent, Harman, Joe, Jacobsen, Sten Eirik, De Bruijn, Marella

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LACK OF BLOOD FLOW BLOCKS MOUSE HSC DEVELOPMENT AT THE PRO-HSC STAGE by Azzoni, Emanuele, Frontera, Vincent, Deltcheva, Elitza, James, Chela, Brown, John, Harman, Joe, Jacobsen, Sten Eirik, Enver, Tariq, de Bruijn, Marella

“…Hematopoietic stem cells (HSCs) emerge from aortic hemogenic endothelium through a continuum of precursors, the pro- and pre-HSCs. Studies in zebrafish have…”
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Function of Junctional Adhesion Molecules (JAMs) in Leukocyte Migration and Homeostasis by Arcangeli, Marie-Laure, Frontera, Vincent, Aurrand-Lions, Michel

“…Homeostasis is a word widely used in the scientific community to refer to the property of a system to maintain its uniformity and functionality. In living…”
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Embryonic hematopoietic progenitors depend on kit ligand for in vivo expansion and differentiation by Azzoni, Emanuele, McGrath, Kathleen, Frontera, Vincent, Harman, Joe, Carrelha, Joana, Nerlov, Claus, Palis, James, Jacobsen, Sten Eirik, Bruijn, Marella Dr

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Cutting edge: JAM-C controls homeostatic chemokine secretion in lymph node fibroblastic reticular cells expressing thrombomodulin by Frontera, Vincent, Arcangeli, Marie-Laure, Zimmerli, Claudia, Bardin, Florence, Obrados, Elodie, Audebert, Stéphane, Bajenoff, Marc, Borg, Jean-Paul, Aurrand-Lions, Michel

“…The development and maintenance of secondary lymphoid organs, such as lymph nodes, occur in a highly coordinated manner involving lymphoid chemokine production…”
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