Search Results - "Fromigué, O."
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TRIB3: A new transcriptional target gene of rapalogs, modulating their effects on splicing
Published in Annals of oncology (01-09-2018)Get full text
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Sp1/Sp3 and the myeloid zinc finger gene MZF1 regulate the human N-cadherin promoter in osteoblasts
Published in Experimental cell research (2005)“…To determine the molecular mechanisms by which N-cadherin transcription is regulated, we cloned and sequenced a 3681-bp of the 5′-flanking region of the human…”
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Bone Morphogenetic Protein-2 Promotes Osteoblast Apoptosis through a Smad-independent, Protein Kinase C-dependent Signaling Pathway
Published in The Journal of biological chemistry (03-08-2001)“…Bone morphogenetic protein-2 (BMP-2), a member of the transforming growth factor-β (TGF-β) family, regulates osteoblast differentiation and bone formation…”
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The LIM-only protein FHL2 controls osteoblast mesenchymal cell differentiation through non-canonical Wnt signalling
Published in Bone (New York, N.Y.) (01-05-2012)Get full text
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The LIM-only protein FHL2 controls mesenchymal cell osteogenic differentiation and bone formation through Wnt5a and Wnt10b
Published in Bone (New York, N.Y.) (01-12-2012)Get full text
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Bone morphogenetic protein-2 and transforming growth factor-β2 interact to modulate human bone marrow stromal cell proliferation and differentiation
Published in Journal of cellular biochemistry (15-03-1998)“…Osteoprogenitor cells in the human bone marrow stroma can be induced to differentiate into osteoblasts under stimulation with hormonal and local factors. We…”
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Strontium ranelate promotes osteoblast gene expression through activation of NFAT signaling
Published in Bone (New York, N.Y.) (01-06-2009)Get full text
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Peptide-based activation of alpha5 integrin promotes murine mesenchymal cell osteoblast differentiation and bone formation in vivo
Published in Bone (New York, N.Y.) (01-05-2011)Get full text
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Zinc chelation: a metallothionein 2A’s mechanism of action involved in osteosarcoma cell death and chemotherapy resistance
Published in Cell death & disease (01-10-2013)“…Osteosarcoma is the most common primary tumor of bone occurring in children and adolescents. The histological response to chemotherapy represents a key…”
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Cyr61 silencing reduces vascularization and dissemination of osteosarcoma tumors
Published in Oncogene (11-06-2015)“…Osteosarcoma is the most prevalent primary pediatric cancer-related bone disease. These tumors frequently develop resistance to chemotherapy and are highly…”
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Increased Osteoblast Apoptosis in Apert Craniosynostosis : Role of Protein Kinase C and Interleukin-1
Published in The American journal of pathology (01-05-2001)“…Apert syndrome is an autosomal dominant disorder characterized by premature cranial ossification resulting from fibroblast growth factor receptor-2…”
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RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42 p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation
Published in Cell death and differentiation (01-11-2006)“…Osteosarcoma is the most common primary bone tumour in young adults. Despite improved prognosis, resistance to chemotherapy remains responsible for failure of…”
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Gene expression profiling of normal human pulmonary fibroblasts following coculture with non-small-cell lung cancer cells reveals alterations related to matrix degradation, angiogenesis, cell growth and survival
Published in Oncogene (20-11-2003)“…Increasing evidence supports a major role for the microenvironment in carcinoma formation and progression. The influence of the stroma is partly mediated by…”
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Active stromelysin‐3 (MMP‐11) increases MCF‐7 survival in three‐dimensional Matrigel culture via activation of p42/p44 MAP‐kinase
Published in International journal of cancer (01-09-2003)“…Stromelysin‐3 (ST3) has the characteristic structure of matrix metalloproteinases (MMP), but its substrate specificity and pattern of expression differ…”
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Bisphosphonates influence the proliferation and the maturation of normal human osteoblasts
Published in Journal of endocrinological investigation (01-06-2002)“…The key pharmacological action for the clinical use of bisphosphonates lies in the inhibition of osteoclast-mediated bone resorption. Osteoblasts could be…”
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Plasticity and regulation of human bone marrow stromal osteoprogenitor cells: potential implication in the treatment of age-related bone loss
Published in Histology and histopathology (01-01-2004)“…Human bone marrow stroma contains pluripotent mesenchymal progenitor cells that can give rise to many mesenchymal lineages, including chondroblasts, adipocytes…”
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60PTRIB3: A new transcriptional target gene of rapalogs, modulating their effects on splicing
Published in Annals of oncology (01-09-2018)Get full text
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Repair of critical-size mouse cranial and long bone defects using human adult mesenchymal stromal cells expressing integrin alpha 5
Published in Bone (New York, N.Y.) (01-05-2011)Get full text
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