Search Results - "Froger, N."
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3β-Methoxypregnenolone, a pregnenolone analogue, enhances neurite outgrowth and neuronal plasticity in neuronal culture
Published in European neuropsychopharmacology (01-03-2017)Get full text
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From Arabidopsis thaliana to Brassica napus: development of amplified consensus genetic markers (ACGM) for construction of a gene map
Published in Theoretical and applied genetics (01-12-2002)“…The evolution of genomes can be studied by comparing maps of homologous genes which show changes in nucleic acid sequences and chromosome rearrangements. In…”
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Importance of taurine in maintaining retinal function
Published in Acta ophthalmologica (Oxford, England) (01-08-2013)“…Taurine depletion has been known to induce photoreceptor degeneration since the 70s. Recently, investigating the retinal toxicity of the antiepileptic drug,…”
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Taurine: The comeback of a neutraceutical in the prevention of retinal degenerations
Published in Progress in retinal and eye research (01-07-2014)“…Taurine is the most abundant amino acid in the retina. In the 1970s, it was thought to be involved in retinal diseases with photoreceptor degeneration, because…”
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P.1.023 - 3β-Methoxypregnenolone, a pregnenolone analogue, enhances neurite outgrowth and neuronal plasticity in neuronal culture
Published in European neuropsychopharmacology (01-03-2017)Get full text
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Proinflammatory cytokines released from microglia inhibit gap junctions in astrocytes: potentiation by β‐amyloid
Published in The FASEB journal (01-03-2006)“…Brain inflammation is characterized by a reactive gliosis involving the activation of astrocytes and microglia. This process, common to many brain injuries and…”
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3β Methoxypregnenolone (MAP4343), a synthetic pregnenolone derivative, promotes neuronal and synaptic plasticity in vitro
Published in European neuropsychopharmacology (01-10-2017)Get full text
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SHOC1, an XPF Endonuclease-Related Protein, Is Essential for the Formation of Class I Meiotic Crossovers
Published in Current biology (23-09-2008)“…Crossovers (COs) are essential for the completion of meiosis in most species and lead to new allelic combinations in gametes [1]. Two pathways of meiotic…”
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Possible future strategies in Neuroprotection
Published in Acta ophthalmologica (Oxford, England) (01-09-2014)“…Retinal ganglion cell (RGC) degeneration is causing blindness in retinal diseases like glaucoma. However, all therapeutic strategies in glaucoma are targeting…”
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Microglial activation in a rat model of NAION
Published in Acta ophthalmologica (Oxford, England) (01-09-2014)“…Purpose Nonarteritic anterior ischemic optic neuropathy (NAION) is the most common optic neuropathy over 50 years and there is no treatment for this condition…”
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Neurochemical and Behavioral Alterations in Glucocorticoid Receptor-Impaired Transgenic Mice after Chronic Mild Stress
Published in The Journal of neuroscience (17-03-2004)“…Mice (GR-i) bearing a transgene encoding a glucocorticoid receptor (GR) antisense RNA under the control of a neuron-specific neurofilament promoter were used…”
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5-Hydroxytryptamine (5-HT)1A Autoreceptor Adaptive Changes in Substance P (Neurokinin 1) Receptor Knock-Out Mice Mimic Antidepressant-Induced Desensitization
Published in The Journal of neuroscience (15-10-2001)“…Antagonists at substance P receptors of the neurokinin 1 (NK1) type have been shown to represent a novel class of antidepressant drugs, with comparable…”
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Minocycline as a new neuroprotective agent in a rodent model of NAION
Published in Acta ophthalmologica (Oxford, England) (01-08-2013)“…Purpose To study the neuroprotective properties of minocycline in a rodent model of NAION. Methods 6 weeks old Long Evans male rats had induction of NAION in…”
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Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice
Published in Journal of neurochemistry (01-04-2004)“…Substance P antagonists of the neurokinin‐1 receptor type (NK1) are gaining growing interest as new antidepressant therapies. It has been postulated that these…”
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FANCM Limits Meiotic Crossovers
Published in Science (American Association for the Advancement of Science) (22-06-2012)“…The number of meiotic crossovers (COs) is tightly regulated within a narrow range, despite a large excess of molecular precursors. The factors that limit COs…”
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Sustained pharmacological blockade of NK1 substance P receptors causes functional desensitization of dorsal raphe 5‐HT1A autoreceptors in mice
Published in Journal of neurochemistry (01-12-2005)“…Antagonists at NK1 substance P receptors have demonstrated similar antidepressant properties in both animal paradigms and in human as selective serotonin…”
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Proinflammatory cytokines released from microglia inhibit gap junctions in astrocytes: Potentiation by ss-amyloid
Published in The FASEB journal (01-03-2006)“…In astrocytes, gap junctions provide an important mode of intercellular communication involved in several glial functions, including neuroprotection. We have…”
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