Search Results - "Froehlich, Matthias"
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Case Report: Effectiveness of secukinumab in systemic sclerosis with early skin progress after autologous hematopoietic stem cell transplantation and end-stage kidney disease
Published in Frontiers in immunology (17-11-2023)“…Autologous hematopoietic stem cell transplantation (aHSCT) represents an effective treatment option in patients with severe forms of systemic sclerosis (SSc)…”
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Drug survival superiority of tumor necrosis factor inhibitors and interleukin-17 inhibitors over Janus kinase inhibitors and interleukin-12/23 inhibitors in German psoriatic arthritis outpatients: retrospective analysis of the RHADAR database
Published in Frontiers in immunology (23-05-2024)“…Treatment options with disease-modifying antirheumatic drugs (DMARDs) for psoriatic arthritis (PsA) have evolved over recent years. In addition to Janus kinase…”
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Use of Janus kinase inhibitors before and after European Medicines Agency safety recommendations: a retrospective study
Published in Frontiers in immunology (22-08-2024)“…Safety recommendations for Janus kinase inhibitors (JAKi) issued by the European Medical Agency (EMA) in 2023 could potentially influence treatment patterns…”
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Immunological Adverse Events After Autologous Hematopoietic Stem Cell Transplantation in Systemic Sclerosis Patients
Published in Frontiers in immunology (03-09-2021)“…Autologous hematopoietic stem cell transplantation (aHSCT) represents an effective treatment for systemic sclerosis (SSc), but it also can cause immunological…”
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Differences in rate and medical indication of caesarean section between Germany and Japan
Published in Pediatrics international (01-09-2020)“…Background There are growing concerns about the increasing rate of caesarean section (CS) worldwide. Various strategies have been implemented to reduce the…”
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Simulated Hypergravity Activates Hemostasis in Healthy Volunteers
Published in Journal of the American Heart Association (15-12-2020)“…Background Hypergravity may promote human hemostasis thereby increasing thrombotic risk. Future touristic suborbital spaceflight will expose older individuals…”
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Autologous Stem Cell Transplantation in Common Variable Immunodeficiency: A Case of Successful Treatment of Severe Refractory Autoimmune Encephalitis
Published in Frontiers in immunology (25-06-2020)“…Common variable immunodeficiency (CVID) is the most common primary immunodeficiency in adults. It is associated with hypogammaglobulinemia, recurring…”
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Patient-reported outcomes provide evidence for increased depressive symptoms and increased mental impairment in giant cell arteritis
Published in Frontiers in medicine (2023)“…The spectrum of giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) represents highly inflammatory rheumatic diseases. Patients mostly report severe…”
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Epidemiology and risk factors of multiple-organ failure after multiple trauma: an analysis of 31,154 patients from the TraumaRegister DGU
Published in The journal of trauma and acute care surgery (01-04-2014)“…In the severely injured who survive the early posttraumatic phase, multiple-organ failure (MOF) is the main cause of morbidity and mortality. An enhanced…”
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Sex-Specific Long-Term Trends in Length of Hospital Stay, Postmenstrual Age at Discharge, and Survival in Very Low Birth Weight Infants
Published in Neonatology (Basel, Switzerland) (01-08-2021)“…In very low birth weight (<1,500 g, VLBW) infants, morbidity and mortality have decreased substantially during the past decades, and both are known to be lower…”
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The impact of prehospital tranexamic acid on mortality and transfusion requirements: match-pair analysis from the nationwide German TraumaRegister DGU
Published in Critical care (London, England) (04-08-2021)“…Outcome data about the use of tranexamic acid (TXA) in civilian patients in mature trauma systems are scarce. The aim of this study was to determine how…”
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Global Coagulation Testing in Acute Care Medicine: Back to Bedside?
Published in Hamostaseologie (01-12-2022)“…Detailed and decisive information about the patients' coagulation status is important in various emergency situations. Conventional global coagulation testing…”
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Calprotectin (S100A8/S100A9) detects inflammatory activity in rheumatoid arthritis patients receiving tocilizumab therapy
Published in Arthritis research & therapy (19-08-2022)“…Abstract Background Assessing serological inflammation is difficult in tocilizumab (TCZ)-treated rheumatoid arthritis (RA) patients, as standard inflammation…”
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Heterodimerization of serotonin receptors 5-HT1A and 5-HT7 differentially regulates receptor signalling and trafficking
Published in Journal of cell science (15-05-2012)“…Serotonin receptors 5-HT(1A) and 5-HT(7) are highly coexpressed in brain regions implicated in depression. However, their functional interaction has not been…”
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Vasa vasorum of proximal cerebral arteries after dural crossing — potential imaging confounder in diagnosing intracranial vasculitis in elderly subjects on black-blood MRI
Published in European radiology (01-02-2022)“…Objectives Vessel wall enhancement (VWE) may be commonly seen on MRI images of asymptomatic subjects. This study aimed to characterize the VWE of the proximal…”
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MRVAS-introducing a standardized magnetic resonance scoring system for assessing the extent of inflammatory burden in giant cell arteritis
Published in Rheumatology (Oxford, England) (01-10-2024)“…Our aim was to introduce a standardized system for assessing the extent of GCA on MRI, i.e. the Magnetic Resonance Vasculitis Activity Score (MRVAS). To obtain…”
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"Auditory scene analysis" in hearing instruments
Published in The Journal of the Acoustical Society of America (01-05-2008)“…The term "auditory scene analysis" generally refers to a categorization of a given acoustic situation based on the acoustic signal only, where the results…”
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High-resolution Magnetic Resonance Imaging visualizes intracranial large artery involvement in Giant Cell Arteritis
Published in Rheumatology (Oxford, England) (10-01-2024)“…Giant Cell arteritis (GCA) is a large vessel vasculitis, typically involving the aorta and its branches with predilection for the scalp arteries. Intracranial…”
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Intraorbital findings in giant cell arteritis on black blood MRI
Published in European radiology (01-04-2023)“…Objective Blindness is a feared complication of giant cell arteritis (GCA). However, the spectrum of pathologic orbital imaging findings on magnetic resonance…”
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The exercise-app Axia for axial spondyloarthritis enhances the home-based exercise frequency in axial spondyloarthritis patients – A cross-sectional survey
Published in Rheumatology international (01-06-2024)“…Background: Patients with axial spondyloarthritis (axSpA) benefit from regular home-based exercise (HbE). In spite of recommendations, a relevant proportion of…”
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