Search Results - "Frodsham, Angela"

A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis by Khan, Amir, Sow, Oumou Y, Lienhardt, Christian, Day, Nicholas P, Grignani, Robert T, Maitland, Kathryn, Vannberg, Fredrik O, Williams, Thomas N, Crook, Derrick W, Aucan, Christophe, Segal, Shelley, Peshu, Nobert, Aaby, Peter, O'Neill, Luke A J, Kyrieleis, Otto, Moore, Catrin E, Sillah, Jackson, Chapman, Stephen J, Walley, Andrew J, Khor, Chiea C, Dunne, Aisling, Scott, Anthony, Campbell, Sarah J, Murphy, Caroline, Yala, Djamel, Berkley, James A, Ling, Edmund Y, Frodsham, Angela J, Knox, Kyle, Davies, Robert J O, Marsh, Kevin, Hill, Adrian V S, Kwiatkowski, Dominic P, Sirugo, Giorgio

“…Toll-like receptors (TLRs) and members of their signaling pathway are important in the initiation of the innate immune response to a wide variety of pathogens…”
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Consanguinity and susceptibility to infectious diseases in humans by Lyons, Emily J., Frodsham, Angela J., Zhang, Lyna, Hill, Adrian V.S., Amos, William

“…Studies of animal populations suggest that low genetic heterozygosity is an important risk factor for infection by a diverse range of pathogens, but relatively…”
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Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP‐2, with outcome of HCV infection by Hellier, Simon, Frodsham, Angela J., Hennig, Branwen J. W., Klenerman, Paul, Knapp, Suzanne, Ramaley, Patricia, Satsangi, Jack, Wright, Mark, Zhang, Lyna, Thomas, Howard C., Thursz, Mark, Hill, Adrian V. S.

“…The effect of host genetic variation on the outcome of hepatitis C virus (HCV) infection and its treatment is poorly understood. The chemokine receptors CCR5,…”
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Class II Cytokine Receptor Gene Cluster Is a Major Locus for Hepatitis B Persistence by Frodsham, Angela J., Zhang, Lyna, Dumpis, Uga, Taib, Nor Azizah Mohd, Best, Steve, Durham, Andrew, Hennig, Branwen J. W., Hellier, Simon, Knapp, Susanne, Wright, Mark, Chiaramonte, Maria, Bell, John I., Graves, Mary, Whittle, Hilton C., Thomas, Howard C., Thursz, Mark R., Hill, Adrian V. S.

“…Persistent hepatitis B virus infection is a major risk factor for hepatocellular carcinoma, the most frequent cancer in some developing countries. Up to 95% of…”
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Host genetics and the outcome of hepatitis B viral infection by Frodsham, Angela J.

“…Hepatitis B Virus (HBV) infection can result in numerous different clinical outcomes. A complex combination of environment, and viral and host genetic factors…”
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Genetics of infectious diseases by Frodsham, Angela J., Hill, Adrian V.S.

“…Infectious diseases represent a major health problem worldwide, both in terms of morbidity and mortality. A complex combination of environmental, pathogen and…”
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Interleukin-10 promoter polymorphisms and the outcome of hepatitis C virus infection by Knapp, Susanne, Hennig, Branwen J W, Frodsham, Angela J, Zhang, Lyna, Hellier, Simon, Wright, Mark, Goldin, Rob, Hill, Adrian V S, Thomas, Howard C, Thursz, Mark R

“…The natural outcome and response to treatment in hepatitis C virus (HCV) infection varies between individuals. Whereas some variation may be attributable to…”
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Influence of IL-10RA and IL-22 polymorphisms on outcome of hepatitis C virus infection by Hennig, Branwen J., Frodsham, Angela J., Hellier, Simon, Knapp, Susanne, Yee, Leland J., Wright, Mark, Zhang, Lyna, Thomas, Howard C., Thursz, Mark, Hill, Adrian V.

“…Background: Two receptor chains, IL‐10RA and IL‐10RB, are known to mediate the functions of interleukin‐10 (IL‐10), which has been shown to be involved in the…”
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Online genetic databases informing human genome epidemiology by Frodsham, Angela J, Higgins, Julian P T

“…With the advent of high throughput genotyping technology and the information available via projects such as the human genome sequencing and the HapMap project,…”
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Inverse Associations of Human Leukocyte Antigen and Malaria Parasite Types in Two West African Populations by KAREN YOUNG, FRODSHAM, Angela, DOUMBO, Ogobara K, GUPTA, Sunetra, DOLO, Amagana, JIANG TING HU, ROBSON, Kathryn J. H, CRISANTI, Andrea, HILL, Adrian V. S, GILBERT, Sarah C

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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IκB genetic polymorphisms and invasive pneumococcal disease by CHAPMAN, Stephen J, KHOR, Chiea C, DENNY, Paul, DAY, Nicholas P, CROOK, Derrick W, DAVIES, Robert J. O, HILL, Adrian V. S, VANNBERG, Fredrik O, FRODSHAM, Angela, WALLEY, Andrew, MASKELL, Nicholas A, DAVIES, Christopher W. H, SEGAL, Shelley, MOORE, Catrin E, GILLESPIE, Stephen H

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Identification of a Major Susceptibility Locus on Chromosome 6p and Evidence for Further Disease Loci Revealed by a Two Stage Genome-Wide Search in Psoriasis by Trembath, Richard C., Lee Clough, R., Rosbotham, Jane L., Jones, Andrew B., Camp, Richard D. R., Frodsham, Angela, Browne, Julie, Barber, Ruth, Terwilliger, Joseph, Mark Lathrop, G., Barker, Jonathan N. W. N.

“…Psoriasis is a common chronic inflammatory disorder of the skin. To further understand the pathogenesis of psoriasis we have chosen to investigate the…”
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I{kappa}B Genetic Polymorphisms and Invasive Pneumococcal Disease by Chapman, Stephen J, Khor, Chiea C, Vannberg, Fredrik O, Frodsham, Angela, Walley, Andrew, Maskell, Nicholas A, Davies, Christopher W. H, Segal, Shelley, Moore, Catrin E, Gillespie, Stephen H, Denny, Paul, Day, Nicholas P, Crook, Derrick W, Davies, Robert J. O, Hill, Adrian V. S

“…Increasing evidence supports a key role for the transcription factor nuclear factor (NF)-kappaB in the host response to pneumococcal infection. Control of…”
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IkappaB genetic polymorphisms and invasive pneumococcal disease by Chapman, Stephen J, Khor, Chiea C, Vannberg, Fredrik O, Frodsham, Angela, Walley, Andrew, Maskell, Nicholas A, Davies, Christopher W H, Segal, Shelley, Moore, Catrin E, Gillespie, Stephen H, Denny, Paul, Day, Nicholas P, Crook, Derrick W, Davies, Robert J O, Hill, Adrian V S

“…Increasing evidence supports a key role for the transcription factor nuclear factor (NF)-kappaB in the host response to pneumococcal infection. Control of…”
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A functional variant in TIRAP, also known as MAL, and protection against invasive pneumococcal disease, bacteraemia, malaria and tuberculosis by Khor, Chiea C., Chapman, Stephen J., Vannberg, Fredrik O, Dunne, Aisling, Murphy, Caroline, Ling, Edmund Y, Frodsham, Angela J., Walley, Andrew J, Kyrieleis, Otto, Khan, Amir, Aucan, Christophe, Segal, Shelley, Moore, Catrin E., Knox, Kyle, Campbell, Sarah J., Lienhardt, Christian, Scott, Anthony, Aaby, Peter, Sow, Oumou Y., Grignani, Robert T., Sillah, Jackson, Sirugo, Girogio, Peshu, Nobert, Williams, Thomas N., Maitland, Kathryn, Davies, Robert J. O., Kwiatkowski, Dominic P., Day, Nicholas P., Yala, Djamel, Crook, Derrick W., Marsh, Kevin, Berkley, James A, O’Neill, Luke A.J., Hill, Adrian V. S.

“…Toll-like receptors (TLRs) and members of their signalling pathway play an important role in the initiation of the innate immune response to a wide variety of…”
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A Μal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis by KHOR, Chiea C, CHAPMAN, Stephen J, AUCAN, Christophe, SEGAL, Shelley, MOORE, Catrin E, KNOX, Kyle, CAMPBELL, Sarah J, LIENHARDT, Christian, SCOTT, Anthony, AABY, Peter, SOW, Oumou Y, GRIGNANI, Robert T, VANNBERG, Fredrik O, SILLAH, Jackson, SIRUGO, Giorgio, PESHU, Nobert, WILLIAMS, Thomas N, MAITLAND, Kathryn, DAVIES, Robert J. O, KWIATKOWSKI, Dominic P, DAY, Nicholas P, YALA, Djamel, CROOK, Derrick W, DUNNE, Aisling, MARSH, Kevin, BERKLEY, James A, O'NEILL, Luke A. J, HILL, Adrian V. S, MURPHY, Caroline, LING, Edmund Y, FRODSHAM, Angela J, WALLEY, Andrew J, KYRIELEIS, Otto, KHAN, Amir

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Genetic linkage of mild malaria to the major histocompatibility complex in Gambian children: study of affected sibling pairs by Jepson, Annette, Sisay-Joof, Fatoumatta, Banya, Winston, Hassan-King, Musa, Frodsham, Angela, Bennett, Stephen, Hill, Adrian, Whittle, Hilton

“…Analysis was by GAS (Genetic Analysis System, version 1.6; Alan Young, Oxford) and the MAPMAKER/SIBS program, which uses a maximum likelihood method that takes…”
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Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP-2, with outcome of HCV infection by Hellier, Simon, Frodsham, Angela J., Hennig, Branwen J.W., Klenerman, Paul, Knapp, Suzanne, Ramaley, Patricia, Satsangi, Jack, Wright, Mark, Zhang, Lyna, Thomas, Howard C., Thursz, Mark, Hill, Adrian V.S.

“…The effect of host genetic variation on the outcome of hepatitis C virus (HCV) infection and its treatment is poorly understood. The chemokine receptors CCR5,…”
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614 Association of genetic variants of the interferon alpha receptor-2 gene with outcome of treatment of persistant HCV infection by Hellier, Simon, Frodsham, Angela J., Hennig, Branwen J., Knapp, Suzanne, Wright, Mark, Zhang, Lyna, Thomas, Howard C., Thursz, Mark, Hill, Adrian V.S.

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An Empirical Exploration of the (Δμ) 2 Genetic Distance for 213 Human Microsatellite Markers by Cooper, Gillian, Amos, William, Bellamy, Richard, Siddiqui, Mahveen Ruby, Frodsham, Angela, Hill, Adrian V.S., Rubinsztein, David C.

“…Microsatellites are now used ubiquitously as genetic markers. One important application is to the assessment of population subdivision and phylogenetic…”
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