Search Results - "Frkanec, Ruža"

Adamantane in Drug Delivery Systems and Surface Recognition by Štimac, Adela, Šekutor, Marina, Mlinarić-Majerski, Kata, Frkanec, Leo, Frkanec, Ruža

“…The adamantane moiety is widely applied in design and synthesis of new drug delivery systems and in surface recognition studies. This review focuses on…”
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Covalently Conjugated NOD2/TLR7 Agonists Are Potent and Versatile Immune Potentiators by Guzelj, Samo, Weiss, Matjaž, Slütter, Bram, Frkanec, Ruža, Jakopin, Žiga

“…The success of vaccination with subunit vaccines often relies on the careful choice of adjuvants. There is great interest in developing new adjuvants that can…”
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Discovery of Nanomolar Desmuramylpeptide Agonists of the Innate Immune Receptor Nucleotide-Binding Oligomerization Domain-Containing Protein 2 (NOD2) Possessing Immunostimulatory Properties by Gobec, Martina, Tomašič, Tihomir, Štimac, Adela, Frkanec, Ruža, Trontelj, Jurij, Anderluh, Marko, Mlinarič-Raščan, Irena, Jakopin, Žiga

“…Muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, has long been known as the smallest fragment possessing adjuvant activity, on the basis of its…”
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Structural Fine-Tuning of Desmuramylpeptide NOD2 Agonists Defines Their In Vivo Adjuvant Activity by Guzelj, Samo, Nabergoj, Sanja, Gobec, Martina, Pajk, Stane, Klančič, Veronika, Slütter, Bram, Frkanec, Ruža, Štimac, Adela, Šket, Primož, Plavec, Janez, Mlinarič-Raščan, Irena, Jakopin, Žiga

“…We report on the design, synthesis, and biological evaluation of a series of nucleotide-binding oligomerization-domain-containing protein 2 (NOD2)…”
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High-Throughput Method for the Simultaneous Determination of Doxorubicin Metabolites in Rat Urine after Treatment with Different Drug Nanoformulations by Zorić, Lara, Drinković, Nikša, Micek, Vedran, Frkanec, Leo, Türeli, Akif Emre, Günday-Türeli, Nazende, Vinković Vrček, Ivana, Frkanec, Ruža

“…Doxorubicin (DOX) is one of the most effective cytotoxic agents against malignant diseases. However, the clinical application of DOX is limited, due to…”
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Arachidonic Acid Metabolites of CYP450 Enzymes and HIF-1α Modulate Endothelium-Dependent Vasorelaxation in Sprague-Dawley Rats under Acute and Intermittent Hyperbaric Oxygenation by Mihaljević, Zrinka, Matić, Anita, Stupin, Ana, Frkanec, Ruža, Tavčar, Branka, Kelava, Vanja, Tartaro Bujak, Ivana, Kolobarić, Nikolina, Kibel, Aleksandar, Drenjančević, Ines

“…Acetylcholine-induced vasorelaxation (AChIR) and responses to reduced pO (hypoxia-induced relaxation (HIR), 0% O ) were assessed in vitro in aortic rings of…”
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Reconstructed membrane vesicles from the microalga Dunaliella as a potential drug delivery system by Levak Zorinc, Maja, Demir-Yilmaz, Irem, Formosa-Dague, Cecile, Vrana, Ivna, Gašparović, Blaženka, Horvat, Lucija, Butorac, Ana, Frkanec, Ruža, Ivošević DeNardis, Nadica

“…[Display omitted] •Reconstructed membrane vesicles were prepared by hypoosmotic shock of microalgae.•The vesicles were soft, hydrophilic and permeable.•The…”
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Spectroscopic study of L-DOPA and dopamine binding on novel gold nanoparticles towards more efficient drug-delivery system for Parkinson’s disease by Kalčec, Nikolina, Peranić, Nikolina, Barbir, Rinea, Hall, Christopher R., Smith, Trevor A., Sani, Marc Antoine, Frkanec, Ruža, Separovic, Frances, Vinković Vrček, Ivana

“…[Display omitted] •Novel gold nanoparticles (AuNPs) were prepared using adamantyl and peptidoglycan derivatives.•AuNPs binding affinity and loading efficiency…”
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Lipidation of NOD2 Agonists with Adamantane and Stearoyl Moieties Differentially Regulates Their In Vivo Adjuvant Activity by Guzelj, Samo, Šišić, Marcela, Bizjak, Špela, Frkanec, Leo, Frkanec, Ruža, Jakopin, Žiga

“…NOD2 is an innate immune receptor that constitutes an important target for the development of small molecule immunopotentiators with great potential to be used…”
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Functional self-assembled nanovesicles based on β-cyclodextrin, liposomes and adamantyl guanidines as potential nonviral gene delivery vectors by Štimac, Adela, Tokić, Matea, Ljubetič, Ajasja, Vuletić, Tomislav, Šekutor, Marina, PoŽar, Josip, Leko, Katarina, HanŽevački, Marko, Frkanec, Leo, Frkanec, RuŽa

“…Multicomponent self-assembled supramolecular nanovesicles based on an amphiphilic derivative of β-cyclodextrin and phosphatidylcholine liposomes (PC-liposomes)…”
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Early Low-Grade Inflammation Induced by High-Salt Diet in Sprague Dawley Rats Involves Th17/Treg Axis Dysregulation, Vascular Wall Remodeling, and a Shift in the Fatty Acid Profile by Mihalj, Martina, Štefanić, Mario, Mihaljević, Zrinka, Kolobarić, Nikolina, Jukić, Ivana, Stupin, Ana, Matić, Anita, Frkanec, Ruža, Tavčar, Branka, Horvatić, Anita, Drenjančević, Ines

“…Unrestricted increased table salt (NaCl) intake is associated with oxidative stress and inflammation, leading to endothelial dysfunction and atherosclerosis…”
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From algal cells to autofluorescent ghost plasma membrane vesicles by Ivošević DeNardis, Nadica, Pletikapić, Galja, Frkanec, Ruža, Horvat, Lucija, Vernier, P. Thomas

“…•Protocol for isolation of algal ghost vesicles is described.•Reconstructed ghost membrane is autofluorescent.•Nanostructural features of ghost membrane are…”
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Design and syntheses of mono and multivalent mannosyl-lipoconjugates for targeted liposomal drug delivery by Štimac, Adela, Cvitaš, Jelena TrmĿiĿ, Frkanec, Leo, Vugrek, Oliver, Frkanec, Ruža

“…[Display omitted] ⿢Mono-, di- and tetravalent mannosyl-lipoconjugates were designed and synthesized.⿢The interaction of mannosylated liposomal preparations…”
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Syntheses and characterization of liposome-incorporated adamantyl aminoguanidines by Šekutor, Marina, Štimac, Adela, Mlinarić-Majerski, Kata, Frkanec, Ruža

“…A series of mono and bis-aminoguanidinium adamantane derivatives has been synthesized and incorporated into liposomes. They combine two biomedically…”
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Adamantyl ferrocene derivatives: Antioxidant abilities and effects on model lipid membranes by Štimac, Adela, Lapić, Jasmina, Blasina, Valentino, Lukinac, Marija, Djaković, Senka, Crnolatac, Ivo, Frkanec, Leo, Frkanec, Ruža

“…A series of homoannularly and heteroannularly substituted adamantyl ferrocene derivatives has been synthesized and their effects on membrane fluidity were…”
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Surface modified liposomes by mannosylated conjugates anchored via the adamantyl moiety in the lipid bilayer by Štimac, Adela, Šegota, Suzana, Dutour Sikirić, Maja, Ribić, Rosana, Frkanec, Leo, Svetličić, Vesna, Tomić, Srđanka, Vranešić, Branka, Frkanec, Ruža

“…The aim of the present study was to encapsulate mannosylated 1-aminoadamantane and mannosylated adamantyltripeptides, namely…”
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Synthesis and Immunostimulating Properties of Novel Adamant-1-yl Tripeptides by Ribić, Rosana, Habjanec, Lidija, Vranešić, Branka, Frkanec, Ruža, Tomić, Srđanka

“…The aim of this work was to prepare L‐ and D‐(adamant‐1‐yl)‐Gly‐L‐Ala‐D‐isoGln peptides in order to study their adjuvant (immunostimulating) activities…”
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Mannosylated Liposomes with Built-in Peptidoglycan Based Immunomodulators for Subunit Vaccine Formulations by Stimac, Adela, Bendelja, Kreso, Sikiric, Maja Dutour, Frkanec, Leo, Frkanec, Ruza

“…The aim of the present study is preparation of mannosylated liposomes with built-in small molecule immunopotentiators for targeted, receptors mediated,…”
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Adhesion Signals of Phospholipid Vesicles at an Electrified Interface by DeNardis, Nadica Ivošević, Žutić, Vera, Svetličić, Vesna, Frkanec, Ruža

“…General adhesion behavior of phospholipid vesicles was examined in a wide range of potentials at the mercury electrode by recording time-resolved adhesion…”
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Influence of Mannosylation on Immunostimulating Activity of Adamant-1-yl Tripeptide by Ribić, Rosana, Habjanec, Lidija, Frkanec, Ruža, Vranešić, Branka, Tomić, Srđanka

“…The mannosylated derivative of adamant‐1‐yl tripeptide (D‐(Ad‐1‐yl)Gly‐L‐Ala‐D‐isoGln) was prepared to study the effects of mannosylation on adjuvant…”
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