Search Results - "Frizelle, Sandra"

A comparison of DigiGait™ and TreadScan™ imaging systems: assessment of pain using gait analysis in murine monoarthritis by Dorman, Christopher W, Krug, Hollis E, Frizelle, Sandra P, Funkenbusch, Sonia, Mahowald, Maren L

“…Carrageenan-induced arthritis is a painful acute arthritis model that is simple to induce, with peak pain and inflammation occurring at about 3 hours. This…”
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The effect of intra-articular vanilloid receptor agonists on pain behavior measures in a murine model of acute monoarthritis by Abdullah, Mishal, Mahowald, Maren L, Frizelle, Sandra P, Dorman, Christopher W, Funkenbusch, Sonia C, Krug, Hollis E

“…Arthritis is the most common cause of disability in the US, and the primary manifestation of arthritis is joint pain that leads to progressive physical…”
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Gene expression profiling identifies matriptase overexpression in malignant mesothelioma by Hoang, Chuong D, D'Cunha, Jonathan, Kratzke, Marian G, Casmey, Carrie E, Frizelle, Sandra P, Maddaus, Michael A, Kratzke, Robert A

“…We investigated the gene expression profiles of malignant pleural mesothelioma (MPM) specimens to identify novel genes that are potentially involved in the…”
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Pain Behavior Measures to Quantitate Joint Pain and Response to Neurotoxin Treatment in Murine Models of Arthritis by Krug, Hollis E., Frizelle, Sandra, McGarraugh, Pari, Mahowald, Maren L.

“…ABSTRACT Objective.  To evaluate the validity of newly developed pain behavior measures in two murine models of inflammatory arthritis and to determine the…”
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Ras pathway activation in malignant mesothelioma by Patel, Manish R, Jacobson, Blake A, De, Arpita, Frizelle, Sandra P, Janne, Pasi, Thumma, Saritha C, Whitson, Brian A, Farassati, Faris, Kratzke, Robert A

“…Mutations in Ras family genes are rare in malignant mesothelioma. The role of activation of the Ras signaling pathway in the pathogenesis of mesothelioma is…”
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Human lung carcinomas express Fas ligand by NIEHANS, G. A, BRUNNER, T, FRIZELLE, S. P, LISTON, J. C, SALERNO, C. T, KNAPP, D. J, GREEN, D. R, KRATZKE, R. A

“…To reach a clinically detectable size, neoplasms must be able to suppress or evade a host immune response. Activated T cells may enter apoptosis in the…”
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Repression of cap-dependent translation attenuates the transformed phenotype in non-small cell lung cancer both In vitro and In vivo by JACOBSON, Blake A, ALTER, Michael D, POLUNOVSKY, Vitaly A, KRATZKE, Robert A, KRATZKE, Marian G, FRIZELLE, Sandra P, YING ZHANG, PETERSON, Mark S, AVDULOV, Svetlana, MOHORN, Riikka P, WHITSON, Bryan A, BITTERMAN, Peter B

“…Aberrant hyperactivation of the cap-dependent protein synthesis apparatus has been documented in a wide range of solid tumors, including epithelial carcinomas,…”
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Detection of occult micrometastases in non-small cell lung carcinoma by reverse transcriptase-polymerase chain reaction by Salerno, C T, Frizelle, S, Niehans, G A, Ho, S B, Jakkula, M, Kratzke, R A, Maddaus, M A

“…The 5-year survival rate following surgical resection of Stage I or Stage II non-small cell lung carcinoma (NSCLC) is 30% to 50%, probably because of…”
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Mechanisms of G1 checkpoint loss in resected early stage non-small cell lung cancer by ZHOU, Joan X, NIEHANS, Gloria A, SHAR, Alexander, RUBINS, Jeffrey B, FRIZELLE, Sandra P, KRATZKE, Robert A

“…Loss of the G1 checkpoint appears to be extremely common among virtually all neoplasms. A variety of genetic and epigenetic mechanisms have been demonstrated…”
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Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain by Krug, Hollis E, Dorman, Christopher, Blanshan, Nicole, Frizelle, Sandra, Mahowald, Maren

“…Pain is the main cause of disability from arthritis. There is currently an unmet need for adequate treatments for arthritis pain. Pre-clinical models are…”
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Inhibition of Both Mesothelioma Cell Growth and Cdk4 Activity following Treatment with a TATp16INK4a Peptide by FRIZELLE, Sandra P, KRATZKE, Marian G, CARREON, Richard R, ENGEL, Sean C, YOUNGQUIST, Laura, KLEIN, Mark A, FOURRE, Laura, SHEKELS, Laurie L, KRATZKE, Robert A

“…Disruption of the 9p21 locus is common in mesothelioma and leads to loss of both the p16 INK4a and the p14 ARF gene products. This study tested the hypothesis…”
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The analgesic effect of intraarticular OnabotulinumtoxinA in a female murine model of collagenase induced chronic degenerative monoarthritis by Blanshan, Nicole, Mahowald, Maren L., Dorman, Christopher, Frizelle, Sandra, Krug, Hollis E.

“…We previously reported the efficacy of intraarticular (IA) rimabotulinumtoxinB (BoNT/B) in a murine model of chronic degenerative arthritis pain. This study…”
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Analgesic effects of intra-articular botulinum toxin Type B in a murine model of chronic degenerative knee arthritis pain by Anderson, Stephanie, Krug, Hollis, Dorman, Christopher, McGarraugh, Pari, Frizelle, Sandra, Mahowald, Maren

“…To evaluate the analgesic effectiveness of intra-articular botulinum toxin Type B (BoNT/B) in a murine model of chronic degenerative arthritis pain. Chronic…”
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Re-expression of p16INK4a in mesothelioma cells results in cell cycle arrest, cell death, tumor suppression and tumor regression by FRIZELLE, S. P, GRIM, J, ZHOU, J, GUPTA, P, CURIEL, D. T, GERADTS, J, KRATZKE, R. A

“…Absence of expression of the p16IKN4a gene product is commonly observed in mesothelioma tumors and cell lines, while wild-type pRB expression is maintained. We…”
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Effects of Insulin-Like Growth Factor-1 Receptor Inhibition in Mesothelioma by Whitson, Bryan A., Jacobson, Blake A., Frizelle, Sandra, Patel, Manish R., Yee, Douglas, Maddaus, Michael A., Kratzke, Robert A.

“…Malignant mesothelioma is a devastating disease with a poor prognosis. Recent data have shown that insulin-like growth factor-1 receptor (IGF-1R) may play a…”
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Effects of insulin-like growth factor-1 receptor inhibition in mesothelioma. Discussion by WHITSON, Bryan A, JACOBSON, Blake A, FRIZELLE, Sandra, PATEL, Manish R, YEE, Douglas, MADDAUS, Michael A, KRATZKE, Robert A, LINDEN, Philip A, SMYTHE, W. Roy, BOFFA, Daniel J

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P-515 Gene therapy of mesothelioma with p16 peptide therapy by Frizelle, Sandra P., Tricker, Erin M., Kratzke, Marian G., Niehans, Gloria A., Kratzke, Robert A.

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Adenovirus-mediated delivery of p16 to p16-deficient human bladder cancer cells confers chemoresistance to cisplatin and paclitaxel by GRIM, J, D'AMICO, A, FRIZELLE, S, ZHOU, J, KRATZKE, R. A, CURIEL, D. T

“…We have previously established the efficacy of adenoviral gene delivery vectors for the treatment of bladder carcinoma in vivo. In the present work, we…”
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Effects of insulin-like growth factor-1 receptor inhibition in mesothelioma. Thoracic Surgery Directors Association Resident Research Award by Whitson, Bryan A, Jacobson, Blake A, Frizelle, Sandra, Patel, Manish R, Yee, Douglas, Maddaus, Michael A, Kratzke, Robert A

“…Malignant mesothelioma is a devastating disease with a poor prognosis. Recent data have shown that insulin-like growth factor-1 receptor (IGF-1R) may play a…”
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Mechanisms of G 1 checkpoint loss in resected early stage non-small cell lung cancer by Zhou, Joan X, Niehans, Gloria A, Shar, Alexander, Rubins, Jeffrey B, Frizelle, Sandra P, Kratzke, Robert A

“…Loss of the G 1 checkpoint appears to be extremely common among virtually all neoplasms. A variety of genetic and epigenetic mechanisms have been demonstrated…”
Get full text