Search Results - "Fristrom, J W"
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Drosophila Broad-Complex encodes a family of related proteins containing zinc fingers
Published in Genetics (Austin) (01-10-1991)“…The Broad-Complex (BR-C) is essential for metamorphosis in Drosophila melanogaster. This locus is coextensive with the 2B5 ecdysone-responsive early puff and…”
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Autosomal mutations affecting adhesion between wing surfaces in Drosophila melanogaster
Published in Genetics (Austin) (01-05-1997)“…Integrins are evolutionarily conserved transmembrane alpha,beta heterodimeric receptors involved in cell-to-matrix and cell-to-cell adhesions. In Drosophila…”
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3
Interactions and developmental effects of mutations in the broad-complex of Drosophila melanogaster
Published in Genetics (Austin) (01-02-1988)“…The 2B5 region on the X chromosome of Drosophila melanogaster forms an early ecdysone puff at the end of the third larval instar. The region contains a complex…”
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4
Apical cell shape changes during Drosophila imaginal leg disc elongation: a novel morphogenetic mechanism
Published in Development (Cambridge) (01-01-1991)“…Imaginal discs of Drosophila are simple epithelial tissues that undergo dramatic changes in shape during metamorphosis, including elongation to form adult…”
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Blistered: a gene required for vein/intervein formation in wings of Drosophila
Published in Development (Cambridge) (01-09-1994)“…We have characterized the blistered (bs) locus phenotypically, genetically and developmentally using a set of new bs alleles. Mutant defects range from wings…”
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Talin Is Essential for Integrin Function in Drosophila
Published in Developmental cell (01-10-2002)“…We show that the Drosophila gene rhea, isolated because its wing blister phenotype is typical of mutants affecting integrin function, encodes talin. Embryos…”
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Gene within a gene: nested Drosophila genes encode unrelated proteins on opposite DNA strands
Published in Cell (17-01-1986)“…A pupal cuticle protein gene has been found within an intron of a Drosophila gene that encodes three purine pathway enzymatic activities. The intronic gene is…”
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The Pupal Cuticle of Drosophila: Biphasic Synthesis of Pupal Cuticle Proteins in Vivo and in vitro in Response to 20-Hydroxyecdysone
Published in The Journal of cell biology (01-07-1985)“…We investigated the synthesis and localization of Drosophila pupal cuticle proteins by immunochemical techniques using both a complex antiserum and monoclonal…”
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Three neighboring genes interact with the Broad-Complex and the Stubble-stubbloid locus to affect imaginal disc morphogenesis in Drosophila
Published in Genetics (Austin) (01-04-1991)“…The Broad-Complex (BR-C) is a complex regulatory locus at 2B-5 on the X chromosome of Drosophila melanogaster. The wild-type BR-C products are apparent…”
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10
Isolation of genes active during hormone-induced morphogenesis in Drosophila imaginal discs
Published in The Journal of biological chemistry (25-04-1986)“…Mass-isolated Drosophila imaginal discs cultured in vitro undergo morphogenesis (evagination) in response to the insect steroid hormone 20-hydroxyecdysone. In…”
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Site-specific cleavage of basement membrane collagen IV during Drosophila metamorphosis
Published in Development (Cambridge) (01-03-1993)“…Breakdown of basement membranes is an important step in the controlled rearrangement of cells during metamorphosis, cell migration, and metastatic spread of…”
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switch in Broad-Complex zinc-finger isoform expression is regulated posttranscriptionally during the metamorphosis of Drosophila imaginal discs
Published in Developmental biology (10-07-1996)“…The Broad-Complex (BR-C) is a key member of the 20-hydroxyecdysone regulatory hierarchy that coordinates changes in gene expression during Drosophila…”
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The Pupal Cuticle of Drosophila: Differential Ultrastructural Immunolocalization of Cuticle Proteins
Published in The Journal of cell biology (01-01-1986)“…Precise ultrastructural localization of Drosophila melanogaster pupal cuticle proteins (PCPs) was achieved by the immunogold labeling of frozen thin sections…”
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Prepupal differentiation of Drosophila imaginal discs: identification of four genes whose transcripts accumulate in response to a pulse of 20-hydroxyecdysone
Published in Genetics (Austin) (01-10-1988)“…We have isolated and initially characterized a novel set of four genes expressed during the prepupal differentiation of imaginal discs of Drosophila…”
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Relationships between protein isoforms and genetic functions demonstrate functional redundancy at the Broad-Complex during Drosophila metamorphosis
Published in Developmental biology (15-07-1997)“…Metamorphosis in holometabolous insects is an ecdysone-dependent process by which the larval form is replaced by a reproductive, adult form. At the onset of…”
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Mutational Analysis of Stubble-stubbloid Gene Structure and Function in Drosophila Leg and Bristle Morphogenesis
Published in Genetics (Austin) (01-03-2006)“…The Stubble-stubbloid (Sb-sbd) gene is required for ecdysone-regulated epithelial morphogenesis of imaginal tissues during Drosophila metamorphosis. Mutations…”
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Dynamic Expression of Broad-Complex Isoforms Mediates Temporal Control of an Ecdysteroid Target Gene at the Onset of Drosophila Metamorphosis
Published in Developmental biology (01-11-2000)“…Metamorphosis in Drosophila melanogaster is orchestrated by the steroid hormone ecdysone, which triggers a cascade of primary-response transcriptional…”
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Genetic interactions between the RhoA and Stubble-stubbloid loci suggest a role for a type II transmembrane serine protease in intracellular signaling during Drosophila imaginal disc morphogenesis
Published in Genetics (Austin) (01-11-2003)“…The Drosophila RhoA (Rho1) GTPase is essential for postembryonic morphogenesis of leg and wing imaginal discs. Mutations in RhoA enhance leg and wing defects…”
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Ecdysteroid Receptors in Imaginal Discs of Drosophila melanogaster
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1978)“…[3H]Ponasterone A (PNA) of high specific activity has been used to identify and begin characterization of ecdysteroid (formerly called ecdysone) receptors in…”
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Prepupal differentiation in Drosophila: distinct cell types elaborate a shared structure, the pupal cuticle, but accumulate transcripts in unique patterns
Published in Development (Cambridge) (01-08-1989)“…The components of the pupal cuticle are the main differentiation products synthesized by both the larval and adult epidermis during the prepupal period of…”
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