Search Results - "Frisen, J"

Human Adult Neurogenesis: Evidence and Remaining Questions by Kempermann, Gerd, Gage, Fred H., Aigner, Ludwig, Song, Hongjun, Curtis, Maurice A., Thuret, Sandrine, Kuhn, H. Georg, Jessberger, Sebastian, Frankland, Paul W., Cameron, Heather A., Gould, Elizabeth, Hen, Rene, Abrous, D. Nora, Toni, Nicolas, Schinder, Alejandro F., Zhao, Xinyu, Lucassen, Paul J., Frisén, Jonas

“…Renewed discussion about whether or not adult neurogenesis exists in the human hippocampus, and the nature and strength of the supporting evidence, has been…”
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The Age of Olfactory Bulb Neurons in Humans by Bergmann, Olaf, Liebl, Jakob, Bernard, Samuel, Alkass, Kanar, Yeung, Maggie S.Y., Steier, Peter, Kutschera, Walter, Johnson, Lars, Landén, Mikael, Druid, Henrik, Spalding, Kirsty L., Frisén, Jonas

“…Continuous turnover of neurons in the olfactory bulb is implicated in several key aspects of olfaction. There is a dramatic decline postnatally in the number…”
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Evidence for Neurogenesis in the Adult Mammalian Substantia Nigra by Zhao, Ming, Momma, Stefan, Delfani, Kioumars, Carlén, Marie, Cassidy, Robert M., Johansson, Clas B., Brismar, Hjalmar, Shupliakov, Oleg, Frisén, Jonas, Janson, Ann Marie

“…New neurons are generated from stem cells in a few regions of the adult mammalian brain. Here we provide evidence for the generation of dopaminergic projection…”
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Regulation of repulsion versus adhesion by different splice forms of an Eph receptor by Clarke, Diana L, Frisén, Jonas, Holmberg, Johan

“…Eph tyrosine kinase receptors and their membrane-bound ephrin ligands mediate cell interactions and participate in several developmental processes. Ligand…”
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Functional Integration of Adult-Born Neurons by Carlén, Marie, Cassidy, Robert M., Brismar, Hjalmar, Smith, Gregory A., Enquist, Lynn W., Frisén, Jonas

“…Over the past decade, it has become clear that neural stem cells in the adult mammalian brain continuously generate new neurons, predominantly in the…”
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Renal agenesis and the absence of enteric neurons in mice lacking GDNF by Sánchez, Marina P, Silos-Santiago, Inmaculada, Frisén, Jonas, He, Bin, Lira, Sergio A, Barbacid, Mariano

“…Glial-cell-line-derived neurotrophic factor (GDNF) is a potent survival factor for dopaminergic neurons and motor neurons in culture. It also protects these…”
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Safety and efficacy of recombinant human platelet derived growth factor (Rhpdgf) in Parkinson's disease by Paul, G, Zachrisson, O, Varrone, A, Almqvist, P, Jerling, M, Lindh, G, Rehncrona, S, Linderoth, B, Bjartmarz, H, Svensson, M, Mercer, K. Jansson, Forsberg, A, Shafer, L.L, Lang, A.M. Janson, Halldin, C, Svenningsson, P, Widner, H, Frisen, J, Pålhagen, S, Haegerstrand, A

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Clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics by Ratz, Michael, von Berlin, Leonie, Larsson, Ludvig, Martin, Marcel, Westholm, Jakub Orzechowski, La Manno, Gioele, Lundeberg, Joakim, Frisén, Jonas

“…The mammalian brain contains many specialized cells that develop from a thin sheet of neuroepithelial progenitor cells. Single-cell transcriptomics revealed…”
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Differential Expression of mRNAs for Neurotrophins and Their Receptors after Axotomy of the Sciatic Nerve by Funakoshi, Hiroshi, Frisén, Jonas, Barbany, Gisela, Timmusk, Tõnis, Zachrisson, Olof, Valerie M. K. Verge, Persson, Håkan

“…The neurotrophin family includes NGF, brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). Previous studies have…”
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Radiocarbon analysis of neurogenesis in the adult human brain by Spalding, Kl, Bergmann, O., Alkass, K., Buchholz, B., Salehpour, Mehran, Possnert, Göran, Liebl, J., Steier, P., Kutschera, W., Bernard, S., Druid, H., Frisen, J.

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Scar formation in the injured spinal cord - mechanisms and opportunities by Frisen, J

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Characterization of Glial trkB Receptors: Differential Response to Injury in the Central and Peripheral Nervous Systems by Frisen, Jonas, Valerie M. K. Verge, Fried, Kaj, Risling, Marten, Persson, Hakan, Trotter, Jacqueline, Hokfelt, Tomas, Lindholm, Dan

“…In situ hybridization on sections from the adult rat peripheral and central nervous systems demonstrated that trkB mRNA was expressed not only by neurons but…”
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Inferring clonal somatic mutations directed by X chromosome inactivation status in single cells by Demirci, Ilke, Larsson, Anton J M, Chen, Xinsong, Hartman, Johan, Sandberg, Rickard, Frisén, Jonas

“…Analysis of clonal dynamics in human tissues is enabled by somatic genetic variation. Here, we show that analysis of mitochondrial mutations in single cells is…”
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Spatially resolved transcriptomics adds a new dimension to genomics by Larsson, Ludvig, Frisén, Jonas, Lundeberg, Joakim

“…As single-cell omics continue to advance, the field of spatially resolved transcriptomics has emerged with a set of experimental and computational methods to…”
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Neurogenesis and Gliogenesis in Nervous System Plasticity and Repair by Frisen, Jonas

“…The brain constantly changes to store memories and adapt to new conditions. One type of plasticity that has gained increasing interest during the last years is…”
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Retrospective Birth Dating of Cells in Humans by Spalding, Kirsty L., Bhardwaj, Ratan D., Buchholz, Bruce A., Druid, Henrik, Frisén, Jonas

“…The generation of cells in the human body has been difficult to study, and our understanding of cell turnover is limited. Testing of nuclear weapons resulted…”
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Adult neurogenesis in humans- common and unique traits in mammals by Ernst, Aurélie, Frisén, Jonas

“…New neurons are continuously generated in specific regions in the adult brain. Studies in rodents have demonstrated that adult-born neurons have specific…”
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Role of endogenous neural stem cells in spinal cord injury and repair by Stenudd, Moa, Sabelström, Hanna, Frisén, Jonas

“…Spinal cord injury is followed by glial scar formation, which has positive and negative effects on recovery from the lesion. More than half of the astrocytes…”
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p53 suppresses the self-renewal of adult neural stem cells by Meletis, Konstantinos, Wirta, Valtteri, Hede, Sanna-Maria, Nistér, Monica, Lundeberg, Joakim, Frisén, Jonas

“…There is increasing evidence that tumors are heterogeneous and that a subset of cells act as cancer stem cells. Several proto-oncogenes and tumor suppressors…”
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Adult Neurogenesis in Humans by Bergmann, Olaf, Spalding, Kirsty L, Frisén, Jonas

“…Adult neurogenesis appears very well conserved among mammals. It was, however, not until recently that quantitative data on the extent of this process became…”
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