Search Results - "Frisch, Kim"

MALDI MSI Separation of Same Donor's Fingermarks Based on Time of Deposition-A Proof-of-Concept Study by Frisch, Kim, Nielsen, Kristine Lykke, Francese, Simona

“…Despite the advent of DNA profiling, fingerprints still play an important role in suspect identification. However, if single crime scene marks may be…”
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Organocatalytic Diastereo- and Enantioselective Annulation Reactions-Construction of Optically Active 1,2-Dihydroisoquinoline and 1,2-Dihydrophthalazine Derivatives by Frisch, Kim, Landa, Aitor, Saaby, Steen, Jørgensen, Karl Anker

“…Good to high conversions (70–100 %) into optically active tri‐ or tetracyclic nitrogen‐containing compounds 1 based on 1,2‐dihydroisoquinolines and…”
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A Retrospective Metabolomics Analysis of Gamma-Hydroxybutyrate in Humans: New Potential Markers and Changes in Metabolism Related to GHB Consumption by Wang, Tingting, Nielsen, Kirstine L, Frisch, Kim, Lassen, Johan K, Nielsen, Camilla B, Andersen, Charlotte U, Villesen, Palle, Andreasen, Mette F, Hasselstrøm, Jørgen B, Johannsen, Mogens

“…GHB is an endogenous short-chain organic acid presumably also widely applied as a rape and knock out drug in cases of drug-facilitated crimes or sexual…”
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Intravenous and oral copper kinetics, biodistribution and dosimetry in healthy humans studied by [64Cu]copper PET/CT by Kjærgaard, Kristoffer, Sandahl, Thomas Damgaard, Frisch, Kim, Vase, Karina Højrup, Keiding, Susanne, Vilstrup, Hendrik, Ott, Peter, Gormsen, Lars Christian, Munk, Ole Lajord

“…Purpose Copper is essential for enzymatic processes throughout the body. [ 64 Cu]copper ( 64 Cu) positron emission tomography (PET) has been investigated as a…”
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Organocatalytic Asymmetric Deconjugative Michael Additions by Bell, Mark, Frisch, Kim, Jørgensen, Karl Anker

“…The organocatalytic allylic C−C bond-forming addition of activated alkylidenes to acrolein has been achieved with good yield and regio- and enantioselectivity…”
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Reply to: “Obeticholic acid and hepatic bile acids: Excellent study faulty conclusion” by Keiding, Susanne, Frisch, Kim, Hofmann, Alan Frederick

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Obeticholic acid improves hepatic bile acid excretion in patients with primary biliary cholangitis by Kjærgaard, Kristoffer, Frisch, Kim, Sørensen, Michael, Munk, Ole Lajord, Hofmann, Alan Frederick, Horsager, Jacob, Schacht, Anna Christina, Erickson, Mary, Shapiro, David, Keiding, Susanne

“…Obeticholic acid (OCA) is an agonist of the nuclear bile acid receptor farnesoid X receptor, which regulates hepatic bile acid metabolism. We tested whether…”
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On the Evolution of Bile Salts and the Farnesoid X Receptor in Vertebrates by Frisch, Kim, Alstrup, Aage Kristian Olsen

“…In recent decades, our knowledge of bile salts has undergone a vast development, and bile salts are now known not only for their detergent properties that aid…”
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N-(4-[18F]fluorobenzyl)cholylglycine, a potential tracer for positron emission tomography of enterohepatic circulation and drug-induced inhibition of ileal bile acid transport. A proof-of-concept PET/CT study in pigs by Frisch, Kim, Mortensen, Frank Viborg, Munk, Ole Lajord, Gormsen, Lars Christian, Alstrup, Aage Kristian Olsen

“…Enterohepatic circulation (EHC) of conjugated bile acids is an important physiological process crucial for bile acids to function as detergents and signal…”
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Desorption Electrospray Ionization Mass Spectrometry Imaging of Powder-Treated Fingermarks on Forensic Gelatin Lifters and its Application for Separating Overlapping Fingermarks by Frisch, Kim, Nielsen, Kirstine L., Hasselstro̷m, Jo̷rgen B., Fink, Rikke, Rasmussen, Stine V., Johannsen, Mogens

“…Fingermarks are frequently collected at crime scenes by using gelatin lifters for preservation and transport of the marks to a forensic laboratory for…”
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Functional assessment of hepatobiliary secretion by 11C-cholylsarcosine positron emission tomography by Ørntoft, Nikolaj, Frisch, Kim, Ott, Peter, Keiding, Susanne, Sørensen, Michael

“…Positron emission tomography (PET) with 11C-cholylsarcosine (11C-CSar), a radiolabelled synthetic N-methylglycine (sarcosine) conjugate of cholic acid, is a…”
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Functional assessment of hepatobiliary secretion by 11 C-cholylsarcosine positron emission tomography by Ørntoft, Nikolaj, Frisch, Kim, Ott, Peter, Keiding, Susanne, Sørensen, Michael

“…Positron emission tomography (PET) with C-cholylsarcosine ( C-CSar), a radiolabelled synthetic N-methylglycine (sarcosine) conjugate of cholic acid, is a novel…”
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The role of dopaminergic and serotonergic transmission in the processing of primary and monetary reward by Schmidt, Casper, Skandali, Nikolina, Gleesborg, Carsten, Kvamme, Timo L, Schmidt, Hema, Frisch, Kim, Møller, Arne, Voon, Valerie

“…Natural rewards such as erotic stimuli activate common neural pathways with monetary rewards. In human studies, the manipulation of dopamine and serotonin play…”
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Human biodistribution, dosimetry, radiosynthesis and quality control of the bile acid PET tracer [N-methyl-11C]cholylsarcosine by Frisch, Kim, Kjærgaard, Kristoffer, Horsager, Jacob, Schacht, Anna Christina, Munk, Ole Lajord

“…[N-methyl-11C]cholylsarcosine ([11C]CSar) is a tracer for imaging and quantitative assessment of intrahepatic cholestatic liver diseases and drug-induced…”
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Radiosynthesis of N- super(11)C-Methyl-Taurine-Conjugated Bile Acids and Biodistribution Studies in Pigs by PET/CT by Schacht, Anna Christina, Soerensen, Michael, Munk, Ole Lajord, Frisch, Kim

“…During cholestasis, accumulation of conjugated bile acids may occur in the liver and lead to hepatocellular damage. Inspired by our recent development of…”
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Radiosynthesis of N - 11 C-Methyl-Taurine–Conjugated Bile Acids and Biodistribution Studies in Pigs by PET/CT by Schacht, Anna Christina, Sørensen, Michael, Munk, Ole Lajord, Frisch, Kim

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Radiosynthesis of N-^sup 11^C-Methyl-Taurine-Conjugated Bile Acids and Biodistribution Studies in Pigs by PET/CT by Schacht, Anna Christina, Sørensen, Michael, Munk, Ole Lajord, Frisch, Kim

“…During cholestasis, accumulation of conjugated bile acids may occur in the liver and lead to hepatocellular damage. Inspired by our recent development of…”
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The potential use of 2-[18F]fluoro-2-deoxy-D-galactose as a PET/CT tracer for detection of hepatocellular carcinoma by Sørensen, Michael, Frisch, Kim, Bender, Dirk, Keiding, Susanne

“…Purpose The aim of the study was to evaluate the feasibility of using the hepatocyte-specific positron emission tomography (PET) tracer 2-[ 18…”
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Hepatobiliary transport kinetics of the conjugated bile acid tracer 11C-CSar quantified in healthy humans and patients by positron emission tomography by Ørntoft, Nikolaj Worm, Munk, Ole Lajord, Frisch, Kim, Ott, Peter, Keiding, Susanne, Sørensen, Michael

“…[Display omitted] Hepatobiliary secretion of bile acids is an important liver function. Here, we quantified the hepatic transport kinetics of conjugated bile…”
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Hepatobiliary transport kinetics of the conjugated bile acid tracer ^sup 11^C-CSar quantified in healthy humans and patients by positron emission tomography by Ørntoft, Nikolaj Worm, Munk, Ole Lajord, Frisch, Kim, Ott, Peter, Keiding, Susanne, Sørensen, Michael

“…Background & Aims Hepatobiliary secretion of bile acids is an important liver function. Here, we quantified the hepatic transport kinetics of conjugated bile…”
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