Search Results - "Friess, W"

Analysis of antibody self-interaction by bio-layer interferometry as tool to support lead candidate selection during preformulation and developability assessments by Domnowski, M., Hackner, B., Neuber, T., Jaehrling, J., Frieß, W.

“…[Display omitted] Developability assessment of therapeutic mAb candidates before entering CMC development mitigates the risk of later failure because of…”
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Collagen sponges for bone regeneration with rhBMP-2 by Geiger, M, Li, R.H, Friess, W

“…In the US alone, approximately 500,000 patients annually undergo surgical procedures to treat bone fractures, alleviate severe back pain through spinal fusion…”
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Functionally graded materials for biomedical applications by Pompe, W, Worch, H, Epple, M, Friess, W, Gelinsky, M, Greil, P, Hempel, U, Scharnweber, D, Schulte, K

“…Functional gradation is one characteristic feature of living tissue. Bio-inspired materials open new approaches for manufacturing implants for bone…”
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Synthesis, characterization and assessment of suitability of trehalose fatty acid esters as alternatives for polysorbates in protein formulation by Schiefelbein, L., Keller, M., Weissmann, F., Luber, M., Bracher, F., Frieß, W.

“…Trehalose fatty acid esters can be synthesized from natural products in a few step synthesis. These surfactants were evaluated for their potential to stabilize…”
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Stabilization of IgG1 in spray-dried powders for inhalation by Schüle, S., Schulz-Fademrecht, T., Garidel, P., Bechtold-Peters, K., Frieß, W.

“…The protein stabilizing capabilities of spray-dried IgG1/mannitol formulations were evaluated. The storage stability was tested at different residual moisture…”
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Zinc Gluconate in the Treatment of Dysgeusia—a Randomized Clinical Trial by Heckmann, S.M., Hujoel, P., Habiger, S., Friess, W., Wichmann, M., Heckmann, J.G., Hummel, T.

“…In the treatment of dysgeusia, the use of zinc has been frequently tried, with equivocal results. The aim of the present randomized clinical trial, which…”
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New Anti-Infective Coatings of Medical Implants by MATL, F. D, OBERMEIER, A, REPMANN, S, FRIESS, W, STEMBERGER, A, KUEHN, K.-D

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Incidence of epithelial ingrowth in primary and retreatment laser in situ keratomileusis by Caster, Andrew I., MD, Friess, David W., OD, Schwendeman, Frank J., OD

“…Purpose To analyze the risk for clinically significant epithelial ingrowth after primary laser in situ keratomileusis (LASIK) and flap-lift retreatment LASIK…”
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Drug release from collagen matrices including an evolving microstructure by Ray, N., van Noorden, T., Radu, F.A., Friess, W., Knabner, P.

“…Biodegradable collagen matrices have become a promising alternative to traditional drug delivery systems. The relevant mechanisms in controlled drug release…”
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Augmentation of antibiotic activity by low-frequency electric and electromagnetic fields examining Staphylococcus aureus in broth media by Matl, F. D., Obermeier, A., Zlotnyk, J., Friess, W., Stemberger, A., Burgkart, R.

“…Systemic treatment of biomaterial‐associated bacterial infections with high doses of antibiotics is an established therapeutic concept. The purpose of this in…”
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Optimization of a pharmaceutical freeze-dried product and its process using an experimental design approach and innovative process analyzers by De Beer, T.R.M., Wiggenhorn, M., Hawe, A., Kasper, J.C., Almeida, A., Quinten, T., Friess, W., Winter, G., Vervaet, C., Remon, J.P.

“…The aim of the present study was to examine the possibilities/advantages of using recently introduced in-line spectroscopic process analyzers (Raman, NIR and…”
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Basic thermoanalytical studies of insoluble collagen matrices by Friess, W., Lee, G.

“…Insoluble collagen has been utilized as a base material for parenteral drug carrier systems. Information on its physicochemical properties was obtained by…”
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Characterization of absorbable collagen sponges as rhBMP-2 carriers by Friess, W, Uludag, H, Foskett, S, Biron, R, Sargeant, C

“…For clinical use recombinant human bone morphogenetic protein (rhBMP-2) is soaked onto an absorbable collagen sponge (ACS) for bone regeneration. Therefore,…”
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Importance of Using Complementary Process Analyzers for the Process Monitoring, Analysis, and Understanding of Freeze Drying by De Beer, T. R. M, Wiggenhorn, M, Veillon, R, Debacq, C, Mayeresse, Y, Moreau, B, Burggraeve, A, Quinten, T, Friess, W, Winter, G, Vervaet, C, Remon, J. P, Baeyens, W. R. G

“…The aim of the present paper is to demonstrate the importance of using complementary process analyzers (PAT tools) for the process monitoring, analysis, and…”
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Porosity and mechanically optimized PLGA based in situ hardening systems by Schloegl, W., Marschall, V., Witting, M.Y., Volkmer, E., Drosse, I., Leicht, U., Schieker, M., Wiggenhorn, M., Schaubhut, F., Zahler, S., Friess, W.

“…Highly porous in situ hardening systems mechanically stable and elastic. Goal of the present study was to develop and to characterize in situ-hardening, porous…”
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New Anti-infective Coatings of Surgical Sutures Based on a Combination of Antiseptics and Fatty Acids by Matl, F. D., Zlotnyk, J., Obermeier, A., Friess, W., Vogt, S., Büchner, H., Schnabelrauch, H., Stemberger, A., Kühn, K.-D.

“…Wound infection is a complication feared in surgery. The aim of this study was to develop new anti-infective coatings of surgical sutures and to compare the…”
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Delivery Systems for BMPs: Factors Contributing to Protein Retention at an Application Site by Uludag, Hasan, Gao, Tiejun, Porter, Thomas J, Friess, Wolfgang, Wozney, John M

“…BackgroundRecombinant human bone morphogenetic proteins (rhBMPs) are being tested in clinical studies for their capacity to elicit bone formation. Biomaterials…”
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Magnetic Drug Targeting as New Therapeutic Option for the Treatment of Biomaterial Infections by Obermeier, A., Kuchler, S., Matl, F.D., Pirzer, T., Stemberger, A., Mykhaylyk, O., Friess, W., Burgkart, R.

“…Implant-associated infections are a challenging problem in surgery. Bacteria in biofilms are difficult to treat as they are less susceptible to antibiotics or…”
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Residual transglutaminase in collagen – Effects, detection, quantification, and removal by Schloegl, W., Klein, A., Fürst, R., Leicht, U., Volkmer, E., Schieker, M., Jus, S., Guebitz, G.M., Stachel, I., Meyer, M., Wiggenhorn, M., Friess, W.

“…A new ELISA detects high amounts of residual transglutaminase (mTG) in mTG-treated collagen despite intensive washing. Dialysis enables the complete removal of…”
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Effects of processing conditions on the rheological behavior of collagen dispersions by Friess, Wolfgang, Schlapp, Monika

“…Biomedical collagen preparations are mainly based on liquid aqueous preparations either used directly as injectables or transferred for example into solid…”
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