Search Results - "Friesen, Marlin"
-
1
Plasma phospholipid fatty acid concentration and incident coronary heart disease in men and women: the EPIC-Norfolk prospective study
Published in PLoS medicine (01-07-2012)“…The lack of association found in several cohort studies between dietary saturated fat and coronary heart disease (CHD) risk has renewed debate over the link…”
Get full text
Journal Article -
2
Serum α-tocopherol and γ-tocopherol concentrations and prostate cancer risk in the PLCO Screening Trial: a nested case-control study
Published in PloS one (05-07-2012)“…Vitamin E compounds exhibit prostate cancer preventive properties experimentally, but serologic investigations of tocopherols, and randomized controlled trials…”
Get full text
Journal Article -
3
Bioavailability of Sulforaphane from two broccoli sprout beverages: results of a short-term, cross-over clinical trial in Qidong, China
Published in Cancer prevention research (Philadelphia, Pa.) (01-03-2011)“…One of several challenges in design of clinical chemoprevention trials is the selection of the dose, formulation, and dose schedule of the intervention agent…”
Get full text
Journal Article -
4
Serum Lycopene, Other Carotenoids, and Prostate Cancer Risk: a Nested Case-Control Study in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
Published in Cancer epidemiology, biomarkers & prevention (01-05-2007)“…Background: Reports from several studies have suggested that carotenoids, and in particular lycopene, could be prostate cancer–preventive agents. This has…”
Get full text
Journal Article -
5
Aflatoxin-induced TP53 R249S mutation in hepatocellular carcinoma in Thailand: association with tumors developing in the absence of liver cirrhosis
Published in PloS one (04-06-2012)“…Primary Liver Cancer (PLC) is the leading cause of death by cancer among males in Thailand and the 3(rd) among females. Most cases are hepatocellular carcinoma…”
Get full text
Journal Article -
6
Quantification of Sulforaphane Mercapturic Acid Pathway Conjugates in Human Urine by High-Performance Liquid Chromatography and Isotope-Dilution Tandem Mass Spectrometry
Published in Chemical research in toxicology (01-10-2008)“…We report validation of the first high-pressure liquid chromatography isotope-dilution mass spectrometry method to measure sulforaphane (SFN) and its…”
Get full text
Journal Article -
7
TP53 R249S mutation, genetic variations in HBX and risk of hepatocellular carcinoma in The Gambia
Published in Carcinogenesis (New York) (01-11-2012)“…In regions with high prevalence of chronic hepatitis B virus (HBV) infection and dietary aflatoxin B(1) (AFB(1)) exposure, hepatocellular carcinomas (HCCs)…”
Get full text
Journal Article -
8
Dietary fish intake and plasma phospholipid n-3 polyunsaturated fatty acid concentrations in men and women in the European Prospective Investigation into Cancer-Norfolk United Kingdom cohort
Published in The American journal of clinical nutrition (01-12-2006)“…BACKGROUND: The n-3 polyunsaturated fatty acids (n-3 PUFAs) docosahexaenoic acid and eicosapentaenoic acid, found in fish and fish-oil supplements and also…”
Get full text
Journal Article -
9
Association between HBX status, aflatoxin-induced R249S TP53 mutation and risk of hepatocellular carcinoma in a case-control study from Thailand
Published in Cancer letters (30-04-2013)“…Highlights ► HBX often undergoes 3’ truncation upon integration in liver cancer cell genome. ► HBX status was analyzed in cases with or without aflatoxin-TP53…”
Get full text
Journal Article -
10
Seasonal Variation in TP53 R249S-Mutated Serum DNA with Aflatoxin Exposure and Hepatitis B Virus Infection
Published in Environmental health perspectives (01-11-2011)“…Background: Chronic hepatitis B virus (HSV) infection and dietary aflatoxin B₁ (AFB₁) exposure are etiological (actors for hepatocellular carcinoma (HCC) in…”
Get full text
Journal Article -
11
Molecular characteristics of Hepatitis B and chronic liver disease in a cohort of HB carriers from Bamako, Mali
Published in BMC infectious diseases (11-04-2015)“…Hepatitis B (HB) infection is common in Mali. However, there is little information on molecular and biochemical characteristics of HB carriers. A group of 1466…”
Get full text
Journal Article -
12
Association between TP53 R249S mutation and polymorphisms in TP53 intron 1 in hepatocellular carcinoma
Published in Genes chromosomes & cancer (01-10-2013)“…Over 100 single nucleotide polymorphisms (SNP) are validated in the TP53 tumor suppressor gene. They define haplotypes, which may differ in their activities…”
Get full text
Journal Article -
13
Quantitative Comparison of Aflatoxin B1 Serum Albumin Adducts in Humans by Isotope Dilution Mass Spectrometry and ELISA
Published in Cancer epidemiology, biomarkers & prevention (01-04-2006)“…Metabolic activation of the hepatocarcinogenic mycotoxin aflatoxin B 1 (AFB 1 ) results in the covalent attachment of AFB 1 to serum albumin. Digestion of…”
Get full text
Journal Article -
14
Nitration and nitrosation of N-acetyl- l-tryptophan and tryptophan residues in proteins by various reactive nitrogen species
Published in Free radical biology & medicine (01-09-2004)“…Proteins are targets of reactive nitrogen species such as peroxynitrite and nitrogen dioxide. Among the various amino acids in proteins, tryptophan residues…”
Get full text
Journal Article -
15
Insulin-like Growth Factor-II Methylation Status in Lymphocyte DNA and Colon Cancer Risk in the Northern Sweden Health and Disease Cohort
Published in Cancer research (Chicago, Ill.) (01-07-2009)“…Loss of imprinting (LOI) of the insulin-like growth factor II (IGFII) gene is a frequent phenomenon in colorectal tumor tissues. Previous reports indicated…”
Get full text
Journal Article -
16
Serum Retinol and Prostate Cancer Risk: a Nested Case-Control Study in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
Published in Cancer epidemiology, biomarkers & prevention (01-04-2009)“…Vitamin A (retinol) plays a key role in the regulation of cell growth and differentiation, and has been studied as a potential chemopreventive agent for…”
Get full text
Journal Article -
17
Chlorination of guanosine and other nucleosides by hypochlorous acid and myeloperoxidase of activated human neutrophils. Catalysis by nicotine and trimethylamine
Published in The Journal of biological chemistry (02-11-2001)“…Activated human neutrophils secrete myeloperoxidase, which generates HOCl from H2O2 and Cl(-). We have found that various (2'-deoxy)nucleosides react with HOCl…”
Get full text
Journal Article -
18
Ser-249 TP53 mutation in tumour and plasma DNA of hepatocellular carcinoma patients from a high incidence area in the Gambia, west Africa
Published in International journal of cancer (20-06-2004)“…Hepatocellular carcinoma (HCC) is frequent in areas of high exposure to aflatoxin and high prevalence of HBV infection, such as western Africa and south‐east…”
Get full text
Journal Article -
19
Transgenic Expression of Aflatoxin Aldehyde Reductase (AKR7A1) Modulates Aflatoxin B1 Metabolism but not Hepatic Carcinogenesis in the Rat
Published in Toxicological sciences (01-05-2009)“…In both experimental animals and humans, aflatoxin B1 (AFB1) is a potent hepatic toxin and carcinogen against which a variety of antioxidants and experimental…”
Get full text
Journal Article -
20
Formation of Two Novel Estrogen Guanine Adducts and HPLC/MS Detection of 4-Hydroxyestradiol-N 7-Guanine in Human Urine
Published in Chemical research in toxicology (01-08-2008)“…Estrogen−DNA adducts are potential biomarkers for assessing the risk of developing of a number of hormonally modified cancers, including breast cancer…”
Get full text
Journal Article