Search Results - "Fries, Isabelle"

Polymeric Nanoparticles for Increasing Oral Bioavailability of Curcumin by Umerska, Anita, Gaucher, Caroline, Oyarzun-Ampuero, Felipe, Fries-Raeth, Isabelle, Colin, Florence, Villamizar-Sarmiento, María Gabriela, Maincent, Philippe, Sapin-Minet, Anne

“…Despite the promising biological and antioxidant properties of curcumin, its medical applications are limited due to poor solubility in water and low…”
Get full text

Nano or Micro: 3 Different Particles to Deliver and Protect S-Nitrosoglutathione for Oral Route Administration by Yi Zhou, Caroline Gaucher, Isabelle Fries, Marianne Parent

“…As a physiological nitric oxide donor, S-nitrosoglutathione (GSNO) is a promising candidate for several diseases (e.g., stroke and atherosclerosis). However,…”
Get full text

A Smooth Muscle Cell-Based Ferroptosis Model to Evaluate Iron-Chelating Molecules for Cardiovascular Disease Treatment by El Hajj, Sarah, Canabady-Rochelle, Laetitia, Fries-Raeth, Isabelle, Gaucher, Caroline

“…Dysregulation of iron homeostasis causes iron-mediated cell death, recently described as ferroptosis. Ferroptosis is reported in many chronic diseases, such as…”
Get full text

Selenoneine-inspired selenohydantoins with glutathione peroxidase-like activity by Alhasan, Rama, Martins, Guilherme M., de Castro, Pedro P., Saleem, Rahman Shah Zaib, Zaiter, Ali, Fries-Raeth, Isabelle, Kleinclauss, Alexandra, Perrin-Sarrado, Caroline, Chaimbault, Patrick, da Silva Júnior, Eufrânio N., Gaucher, Caroline, Jacob, Claus

“…[Display omitted] Chronic diseases such as cystic fibrosis, inflammatory bowel diseases, rheumatoid arthritis, and cardiovascular illness have been linked to a…”
Get full text

A comparison of epinephrine only, arginine vasopressin only, and epinephrine followed by arginine vasopressin on the survival rate in a rat model of anaphylactic shock by DEWACHTER, Pascale, RAËTH-FRIES, Isabelle, JOUAN-HUREAUX, Valérie, MENU, Patrick, VIGNERON, Claude, LONGROIS, Dan, MERTES, Paul Michel

“…Epinephrine and more recently arginine vasopressin (AVP) alone or in combination have been proposed in patients with anaphylactic shock, but few experimental…”
Get full text

Polymer nanocomposite particles of S-nitrosoglutathione: A suitable formulation for protection and sustained oral delivery by Wu, Wen, Gaucher, Caroline, Fries, Isabelle, Hu, Xian-ming, Maincent, Philippe, Sapin-Minet, Anne

“…[Display omitted] S-nitrosoglutathione (GSNO) is a nitric oxide (NO) donor with therapeutic potential for cardiovascular disease treatment. Chronic oral…”
Get full text

Challenging development of storable particles for oral delivery of a physiological nitric oxide donor by Zhou, Yi, Gaucher, Caroline, Fries, Isabelle, Hobekkaya, Mehmet-Akif, Martin, Charlène, Leonard, Clément, Deschamps, Frantz, Sapin-Minet, Anne, Parent, Marianne

“…Nitric oxide (NO) deficiency is often associated with several acute and chronic diseases. NO donors and especially S-nitrosothiols such as S-nitrosoglutathione…”
Get full text

S-nitrosoglutathione potentiates protein S-nitrosation under oxidative stress, a potential improvement of NO storage into smooth muscle cells by Belcastro, Eugenia, Wu, Wen, Fries, Isabelle, Corti, Alessandro, Pompella, Alfonso, Leroy, Pierre, Lartaud, Isabelle, Gaucher, Caroline

Get full text

P 050 - S-nitrosoglutathione potentiates protein S-nitrosation under oxidative stress, a potential improvement of NO storage into smooth muscle cells by Belcastro, Eugenia, Wu, Wen, Fries, Isabelle, Corti, Alessandro, Pompella, Alfonso, Leroy, Pierre, Lartaud, Isabelle, Gaucher, Caroline

“…Cardiovascular diseases are associated with oxidative stress and reduced nitric oxide (NO) bioavailability. The ability of NO donors like S-nitrosoglutathione…”
Get full text

Time lasting S-nitrosoglutathione polymeric nanoparticles delay cellular protein S-nitrosation by Wu, Wen, Gaucher, Caroline, Diab, Roudayna, Fries, Isabelle, Xiao, Yu-Ling, Hu, Xian-Ming, Maincent, Philippe, Sapin-Minet, Anne

“…[Display omitted] •We encapsulated directly S-nitrosoglutathione (GSNO) within polymeric nanoparticles.•The encapsulation efficiency was around 54% (m/m)…”
Get full text

Higher‐energy collision‐induced dissociation for the quantification by liquid chromatography/tandem ion trap mass spectrometry of nitric oxide metabolites coming from S‐nitroso‐glutathione in an in vitro model of the intestinal barrier by Yu, Haiyan, Bonetti, Justine, Gaucher, Caroline, Fries, Isabelle, Vernex‐Loset, Lionel, Leroy, Pierre, Chaimbault, Patrick

“…Rationale The potency of S‐nitrosoglutathione (GSNO) as a nitric oxide (NO) donor to treat cardiovascular diseases (CVDs) has been highlighted in numerous…”
Get full text

P 168 - Intestine permeability of S-nitrosoglutathione as a potential nitric oxide donor via oral administration by Bonetti, Justine, Yu, Haiyan, Ming, Hui, Sapin-Minet, Anne, Fries, Isabelle, Clarot, Igor, Chaimbault, Patrick, Leroy, Pierre, Gaucher, Caroline

“…Nitric oxide (NO) is a gaseous messenger which plays an important role in the vascular system homeostasis. Its origin includes both endogenous (catabolism of…”
Get full text

Intestine permeability of S-nitrosoglutathione as a potential nitric oxide donor via oral administration by Bonetti, Justine, Yu, Haiyan, Ming, Hui, Sapin-Minet, Anne, Fries, Isabelle, Clarot, Igor, Chaimbault, Patrick, Leroy, Pierre, Gaucher, Caroline

Get full text

Synthesis of S-nitrosoglutathione-alginate for prolonged delivery of nitric oxide in intestines by Shah, Shefaat Ullah, Socha, Marie, Fries, Isabelle, Gibaud, Stéphane

“…S-nitrosothiols are a class of NO-donors currently under investigation for the treatment of various diseases. In this study, we developed a novel NO-donor…”
Get more information

Nitric oxide-eluting scaffolds and their interaction with smooth muscle cells in vitro by Parent, Marianne, Boudier, Ariane, Fries, Isabelle, Gostyńska, Aleksandra, Rychter, Marek, Lulek, Janina, Leroy, Pierre, Gaucher, Caroline

“…Fabrication of scaffolds loaded with nitric oxide (NO) donors (S‐nitrosoglutathione, GSNO, and isosorbide mononitrate, ISMN) with suitable cell compatibility…”
Get full text

Nitric oxide-eluting scaffolds and their interaction with smooth muscle cells in vitro: Nitric oxide-eluting scaffolds for tissue-engineering by Parent, Marianne, Boudier, Ariane, Fries, Isabelle, Gostyńska, Aleksandra, Rychter, Marek, Lulek, Janina, Leroy, Pierre, Gaucher, Caroline

Get full text

Melarsoprol–cyclodextrins inclusion complexes by Gibaud, Stéphane, Zirar, Siham Ben, Mutzenhardt, Pierre, Fries, Isabelle, Astier, Alain

“…Melarsoprol, a water-insoluble drug, is mainly used in the treatment of trypanosomiasis and has demonstrated an in vitro activity on myeloid and lymphoid…”
Get full text

A Smooth Muscle Cell-Based Ferroptosis Model to Evaluate Iron-Chelating Molecules for Cardiovascular Disease Treatment by El Hajj, Sarah, Canabady-Rochelle, Laetitia, Fries-Raeth, Isabelle, Gaucher, Caroline

“…Dysregulation of iron homeostasis causes iron-mediated cell death, recently described as ferroptosis. Ferroptosis is reported in many chronic diseases, such as…”
Get full text

Intestinal absorption of S-nitrosothiols: Permeability and transport mechanisms by Bonetti, Justine, Zhou, Yi, Parent, Marianne, Clarot, Igor, Yu, Haiyan, Fries-Raeth, Isabelle, Leroy, Pierre, Lartaud, Isabelle, Gaucher, Caroline

“…[Display omitted] S-Nitrosothiols, a class of NO donors, demonstrate potential benefits for cardiovascular diseases. Drugs for such chronic diseases require…”
Get full text

(2-Phenyl-[1,3,2]dithiarsolan-4-yl)-methanol derivatives show in vitro antileukemic activity by Gibaud, Stéphane, Alfonsi, Raphaël, Mutzenhardt, Pierre, Fries, Isabelle, Astier, Alain

“…(2-Phenyl-[1,3,2]dithiarsolan-4-yl)-methanol derivatives were tested on K562 and U937 human leukemia cell lines. Their systemic toxicity was estimated by the…”
Get full text