Search Results - "Friery, O. P."

The chemopotentiation of cisplatin by the novel bioreductive drug AQ4N by GALLAGHER, R, HUGHES, C. M, MURRAY, M. M, FRIERY, O. P, PATTERSON, L. H, MCKEOWN, S. R, HIRST, D. G

“…AQ4N is a bioreductive drug that can significantly enhance the anti-tumour effect of radiation and cyclophosphamide. The aim of this study was to examine the…”
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Enhancement of the anti-tumour effect of cyclophosphamide by the bioreductive drugs AQ4N and tirapazamine by FRIERY, O. P, GALLAGHER, R, MURRAY, M. M, HUGHES, C. M, GALLIGAN, E. S, MCINTYRE, I. A, PATTERSON, L. H, HIRST, D. G, MCKEOWN, S. R

“…The ability of the bioreductive drugs AQ4N and tirapazamine to enhance the anti-tumour effect of cyclophosphamide was assessed in three murine tumour models…”
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DNA damage following combination of radiation with the bioreductive drug AQ4N: possible selective toxicity to oxic and hypoxic tumour cells by HEJMADI, M. V, MCKEOWN, S. R, FRIERY, O. P, MCINTYRE, I. A, PATTERSON, L. H, HIRST, D. G

“…AQ4N (1,4-bis-([2-(dimethylamino-N- oxide)ethyl]amino)5,8-dihydroxyanthracene-9,10-dione) is a novel bioreductive agent that can be reduced to a stable,…”
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Evidence for a therapeutic gain when AQ4N or tirapazamine is combined with radiation by McKeown, S R, Friery, O P, McIntyre, I A, Hejmadi, M V, Patterson, L H, Hirst, D G

“…The use of bioreductive drugs as an adjunct to radiotherapy in the treatment of cancer is presently being tested in several clinical trials worldwide. We have…”
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The chemopotentiation of cisplatin by the novel bioreductive drug AQ4N by Gallagher, R, Hughes, C M, Murray, M M, Friery, O P, Patterson, L H, Hirst, D G, McKeown, S R

“…BRITISH JOURNAL OF CANCER: (2002) 87, 1339-1339. doi:10.1038/sj.bjc.6600561 www.bjcancer.com© 2002 Cancer Research UK CORRECTION TO:: British Journal of Cancer…”
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Erratum: The chemopotentiation of cisplatin by the novel bioreductive drug AQ4N by Gallagher, R, Hughes, C M, Murray, M M, Friery, O P, Patterson, L H, Hirst, D G, McKeown, S R

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DNA damage induced in T50/80 tumour cells following exposure to the bioreductive drug Tirapazamine in combination with a single dose of radiation (12Gy) by Friery, O P, Hejmadi, M V, McKeown, S R

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Royal Academy of Medicine in Ireland Section of Biomedical Sciences by Ruddock, W., Burns, D. M., Brown, J. C. W., Allen, J. M., Hirst, D. G., Love, G. P., Keenan, A. K., Lally, C., Bird, A., Ryan, M. P., O’Connor, N., O’Boyle, K. M., McGeown, J. G., McCarron, J. G., Drummond, R. M., Fay, F. S., Connor, T. J., Kelly, J. P., Leonard, B. E., Gilmartin, L., O’Cuinn, G., MacDonncha, C., Watson, A. W. S., McGrath, S., Brady, K. J., McKillen, H-C., Taylor, C. W., Smith, S. K., Thornton, S., Martin, A. D., Bailie, J. R., McKeown, S. R., Higgins, C. A., Hatton, W. J., McKerr, G., Harvey, D., Carson, J., Hannigan, B. M., Morrow, D. M. P., McGlynn, H., Thompson, C. M. G., Higgins, C., Galligan, E. S., Murray, M. M., Leckey, J. L., Nevin, G. B., Soppitt, D. S., Esfandiary, M. H., Gilmore, W. S., Robson, T., Dineen, T., Greer, A., Houghton, J. A., O’Halloran, K. D., Bradford, A., McGuire, M., MacDermott, M., Coogan, A., O’Connor, J. J., Regan, C. S., Redmond, A. M., Harkin, A., Lowe, A. S., Baxter, G. D., Kennovin, G. D., Leek, M., Friery, O. P., Hejmadi, M. V., Patterson, L. H., Robinson, J., Hill, I., Kilbride, J., Cotton, K. D., Hollywood, M. A., McHale, N. G., Thornbury, K. D., Halligan, C. P., O’Connell, D. P., Harvey, B. J., Fanning, P., O’Farrell, A., Cantillon, D., Cryan, J. F., O’Leary, D., O’Malley, D. T., Nolan, A., Moran, A. P., Fitzgerald, K. A., O’Neill, L. A. J., McElligott, A., Baker, A. H., Joyce, K. M., Ruane, T., Hall, W. J., Markos, F., Carey, M. F., Galvin, C., Perl, E. R., Curran, A. K., Connolly, C.

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Royal academy of medicine in Ireland section of biomedical sciences: Proceedings of winter meeting held in Trinity College Dublin, 1996 by Sharma, S., Sharma, S. C., Byrne, P. D., Lyons, J. B., Boylan, J. F., McShane, A. J., Galligan, E. S., Sweetman, S. F., Clements, B. A., Lowe, A. S., McCormack, K. J. M., Walsh, D. M., Baxter, G. D., Allen, J. M., Kelleher, S., Keenan, A. K., Burns, D. M., Brown, J. C. W., Ruddock, M. W., Kennovin, G. D., Dykes, E. L., Flitney, F. W., Hirst, D. G., Winter, D. C., Cuffe, J., O’Sullivan, G. C., Harvey, B. J., Thompson, G. H., Murray, J. M., Brehony, F., Kelly, J. P., Leonard, B. E., Cotton, K. D., Hollywood, M. A., McHale, N. G., Thornbury, K. D., Stapleton, M. T., Allshire, A. P., Freeburn, J. C., Wallace, J. M. W., Sinnamon, D., Craig, B., Strain, J. J., Gilmore, W. S., Lyons, J. D. M, Murray, J., Trinick, T., Fee, J. P. H., Hennessy, L., Watson, A. W. S., Halley, W. L., Weir, M. A., Friery, O. P., Hejmadi, M. V., McIntyre, I. A., McALeer, J. J. A., Patterson, L. H., McKeown, S. R., Leckey, J. L., Nevin, G. B., Soppitt, D. S., Harkin, A. J., Wrynn, A. S., Earley, B., Dineen, T. M., Powell, R., Houghton, J. A., Cantillon, D., McDaid, J., O’Halloran, K. D., Bradford, A., Curran, A. K., Harmon, D., Sweeney, M., McLoughlin, P., O’Leary, D., O’Connor, J. J., Broderick, A. M., Keon, N., Martin, F.

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