Search Results - "Friend, Samantha F."

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    The discovery of a reciprocal relationship between tyrosine-kinase signaling and cullin neddylation by Friend, Samantha F, Peterson, Lisa K, Treacy, Eric, Stefanski, Adrianne L, Sosinowski, Tomasz, Pennock, Nathan D, Berger, Allison J, Winn, Virginia D, Dragone, Leonard L

    Published in PloS one (04-10-2013)
    “…While neddylation is known to activate cullin (CUL)-RING ubiquitin ligases (CRLs), its role in regulating T cell signaling is poorly understood. Using the…”
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    Journal Article
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    C‐Reactive Protein: Marker of risk for post‐traumatic stress disorder and its potential for a mechanistic role in trauma response and recovery by Friend, Samantha F., Nachnani, Rahul, Powell, Susan B., Risbrough, Victoria B.

    Published in The European journal of neuroscience (01-05-2022)
    “…Increasing evidence indicates that inflammation plays a role in PTSD and stress disorder pathophysiology. PTSD is consistently associated with higher…”
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    Journal Article
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    Role of Inflammation in Traumatic Brain Injury–Associated Risk for Neuropsychiatric Disorders: State of the Evidence and Where Do We Go From Here by Risbrough, Victoria B., Vaughn, Melonie N., Friend, Samantha F.

    Published in Biological psychiatry (1969) (01-03-2022)
    “…In the past decade, there has been an increasing awareness that traumatic brain injury (TBI) and concussion substantially increase the risk for developing…”
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    SLAP deficiency increases TCR avidity leading to altered repertoire and negative selection of cognate antigen-specific CD8+ T cells by Friend, Samantha F., Peterson, Lisa K., Kedl, Ross M., Dragone, Leonard L.

    Published in Immunologic research (01-03-2013)
    “…How T cell receptor (TCR) avidity influences CD8 + T cell development and repertoire selection is not yet fully understood. To fill this gap, we utilized…”
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    Journal Article
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    SLAP deficiency decreases dsDNA autoantibody production by Peterson, Lisa K, Pennington, Luke F, Shaw, Laura A, Brown, Meredith, Treacy, Eric C, Friend, Samantha F, Hatlevik, Øyvind, Rubtsova, Kira, Rubtsov, Anatoly V, Dragone, Leonard L

    Published in Clinical immunology (Orlando, Fla.) (01-02-2014)
    “…Abstract Src-like adaptor protein (SLAP) adapts c-Cbl, an E3 ubiquitin ligase, to activated components of the BCR signaling complex regulating BCR levels and…”
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    Journal Article
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    Regulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modifications by Friend, Samantha F, Deason-Towne, Francina, Peterson, Lisa K, Berger, Allison J, Dragone, Leonard L

    “…Post-translational protein modifications are a dynamic method of regulating protein function in response to environmental signals. As with any cellular…”
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    Journal Article
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    SLAP deficiency increases TCR avidity leading to altered repertoire and negative selection of cognate antigen-specific CD8 super(+) T cells by Friend, Samantha F, Peterson, Lisa K, Kedl, Ross M, Dragone, Leonard L

    Published in Immunologic research (01-03-2013)
    “…How T cell receptor (TCR) avidity influences CD8 super(+) T cell development and repertoire selection is not yet fully understood. To fill this gap, we…”
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    Journal Article
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    SLAP deficiency increases TCR avidity leading to altered repertoire and negative selection of cognate antigen-specific CD8^sup +^ T cells by Friend, Samantha F, Peterson, Lisa K, Kedl, Ross M, Dragone, Leonard L

    Published in Immunologic research (01-03-2013)
    “…Issue Title: Special Issue: Mile High Immunology How T cell receptor (TCR) avidity influences CD8^sup +^ T cell development and repertoire selection is not yet…”
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    Journal Article
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