Search Results - "Friedrich, Chloe"
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S162: LOSS OF HEMATOPOIETIC PROGENITORS HETEROGENEITY IS AN ADVERSE PROGNOSTIC FACTOR IN MYELODYSPLASTIC SYNDROMES
Published in HemaSphere (08-08-2023)Get full text
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Subcutaneous azacitidine maintenance in transplantineligible patients with acute myeloid leukemia: a single-center retrospective study
Published in Haematologica (Roma) (01-10-2023)Get full text
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A splenic lymphoma/leukemia with a spontaneous blast decrease without treatment
Published in Blood (02-07-2020)Get full text
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Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19
Published in Cell (17-09-2020)“…Blood myeloid cells are known to be dysregulated in coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2. It is unknown whether the innate myeloid…”
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The Mesenchymal Niche in Myelodysplastic Syndromes
Published in Diagnostics (Basel) (05-07-2022)“…Myelodysplastic syndromes (MDSs) are clonal disorders characterized by ineffective hematopoiesis, resulting in cytopenias and a risk of developing acute…”
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Atypical splice-site mutations causing VEXAS syndrome
Published in Rheumatology (Oxford, England) (01-12-2021)Get full text
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VEXAS syndrome is characterized by inflammasome activation and monocyte dysregulation
Published in Nature communications (30-01-2024)“…Acquired mutations in the UBA1 gene were recently identified in patients with severe adult-onset auto-inflammatory syndrome called VEXAS (vacuoles, E1 enzyme,…”
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Hematopoietic differentiation is characterized by a transient peak of entropy at a single-cell level
Published in BMC biology (09-03-2022)“…Mature blood cells arise from hematopoietic stem cells in the bone marrow by a process of differentiation along one of several different lineage trajectories…”
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Luspatercept (RAP-536) modulates oxidative stress without affecting mutation burden in myelodysplastic syndromes
Published in Annals of hematology (01-12-2022)“…In low-risk myelodysplastic syndrome (LR-MDS), erythropoietin (EPO) is widely used for the treatment of chronic anemia. However, initial response to EPO has…”
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Loss of hematopoietic progenitors heterogeneity is an adverse prognostic factor in lower-risk myelodysplastic neoplasms
Published in Leukemia (01-05-2024)“…Myelodysplastic neoplasms (MDS) are characterized by clonal evolution starting from the compartment of hematopoietic stem and progenitors cells (HSPCs),…”
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Myeloproliferative neoplasms and clonal haematopoiesis in patients with giant cell arteritis: a case–control and exploratory study
Published in Rheumatology (Oxford, England) (02-02-2022)“…Abstract Objectives GCA is a large vessel vasculitis for which triggering factors remain unknown. Clonal haematopoiesis (CH) was associated with…”
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Battle of the clones: paroxysmal nocturnal hemoglobinuria vs myelodysplastic syndrome
Published in Annals of hematology (01-10-2020)Get full text
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PCR‐Fluo‐ASXL1‐FA: A fast, sensitive and inexpensive complementary method to detect ASXL1 mutations in haematological malignancies
Published in International journal of laboratory hematology (01-10-2022)“…Introduction The additional sex combs like 1 (ASXL1) gene is frequently mutated in a number of haematological neoplasms. The c.1934dupG, known to be the most…”
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Acquired spherocytosis due to somatic ANK1 mutations as a manifestation of clonal hematopoiesis in elderly patients
Published in American journal of hematology (01-08-2022)Get full text
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Mastocytosis onset in a patient with treated hairy cell leukemia: Just a coincidence?
Published in Blood cells, molecules, & diseases (01-03-2020)“…Mastocytosis is a mast cell disease caused by functionally defective infiltrating mast cells and CD34+ mast cell precursors. The heterogeneous group of mast…”
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Stabilization of [beta]-catenin upon B-cell receptor signaling promotes NF-kB target genes transcription in mantle cell lymphoma
Published in Oncogene (02-04-2020)“…B-cell receptor (BCR) signaling pathways and interactions with the tumor microenvironment account for mantle cell lymphoma (MCL) cells survival in lymphoid…”
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Effect of Rap-536 on MDS PDX-Murine Models with or without SF3B1 Mutation
Published in Blood (13-11-2019)“…Introduction: Anemia is the most frequent cytopenia in myelodysplastic syndromes (MDS) and patients will require red blood cell transfusion. Most low-risk MDS…”
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