Search Results - "Friedel, Miriam"

4D MEMRI atlas of neonatal FVB/N mouse brain development by Szulc, Kamila U., Lerch, Jason P., Nieman, Brian J., Bartelle, Benjamin B., Friedel, Miriam, Suero-Abreu, Giselle A., Watson, Charles, Joyner, Alexandra L., Turnbull, Daniel H.

“…The widespread use of the mouse as a model system to study brain development has created the need for noninvasive neuroimaging methods that can be applied to…”
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PPARγ agonists improve survival and neurocognitive outcomes in experimental cerebral malaria and induce neuroprotective pathways in human malaria by Serghides, Lena, McDonald, Chloe R, Lu, Ziyue, Friedel, Miriam, Cui, Cheryl, Ho, Keith T, Mount, Howard T J, Sled, John G, Kain, Kevin C

“…Cerebral malaria (CM) is associated with a high mortality rate, and long-term neurocognitive impairment in approximately one third of survivors. Adjunctive…”
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Effects of Surface Tethering on Protein Folding Mechanisms by Friedel, Miriam, Baumketner, Andrij, Shea, Joan-Emma

“…The folding mechanisms of proteins are increasingly being probed through single-molecule experiments in which the protein is immobilized on a surface…”
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Separate effects of sex hormones and sex chromosomes on brain structure and function revealed by high-resolution magnetic resonance imaging and spatial navigation assessment of the Four Core Genotype mouse model by Corre, Christina, Friedel, Miriam, Vousden, Dulcie A., Metcalf, Ariane, Spring, Shoshana, Qiu, Lily R., Lerch, Jason P., Palmert, Mark R.

“…Males and females exhibit several differences in brain structure and function. To examine the basis for these sex differences, we investigated the influences…”
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Loss of T cells influences sex differences in behavior and brain structure by Rilett, Kelly C, Friedel, Miriam, Ellegood, Jacob, MacKenzie, Robyn N, Lerch, Jason P, Foster, Jane A

“…Highlights • T cell deficient mice show reduced exploratory and anxiety-like behaviours. • Loss of T cells led to loss of sexual dimorphisms in behavior and…”
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Comparing homologous microscopic sections from multiple embryos using HREM by Henkelman, R. Mark, Friedel, Miriam, Lerch, Jason P., Wilson, Robert, Mohun, Timothy

“…•3D HREM embryo images can be registered.•Homologous microscopic sections can be obtained from multiple embryos.•Anatomical phenotypes can be analyzed by…”
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Pydpiper: a flexible toolkit for constructing novel registration pipelines by Friedel, Miriam, van Eede, Matthijs C, Pipitone, Jon, Chakravarty, M Mallar, Lerch, Jason P

“…Using neuroimaging technologies to elucidate the relationship between genotype and phenotype and brain and behavior will be a key contribution to biomedical…”
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Stability of a protein tethered to a surface by Friedel, Miriam, Baumketner, Andrij, Shea, Joan-Emma

“…Surface-tethered proteins are increasingly being used in a variety of experimental situations, and they are the basis for many new technologies. Nevertheless,…”
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Widespread Volumetric Brain Changes following Tooth Loss in Female Mice by Avivi-Arber, Limor, Seltzer, Ze'ev, Friedel, Miriam, Lerch, Jason P, Moayedi, Massieh, Davis, Karen D, Sessle, Barry J

“…Tooth loss is associated with altered sensory, motor, cognitive and emotional functions. These changes vary highly in the population and are accompanied by…”
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Adolescent cocaine exposure causes enduring macroscale changes in mouse brain structure by Wheeler, Anne L, Lerch, Jason P, Chakravarty, M Mallar, Friedel, Miriam, Sled, John G, Fletcher, Paul J, Josselyn, Sheena A, Frankland, Paul W

“…Cocaine dependence is associated with abnormalities in brain structure in humans. However, it is unclear whether these differences in brain structure…”
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PPAR[gamma] Agonists Improve Survival and Neurocognitive Outcomes in Experimental Cerebral Malaria and Induce Neuroprotective Pathways in Human Malaria: e1003980 by Serghides, Lena, McDonald, Chloe R, Lu, Ziyue, Friedel, Miriam, Cui, Cheryl, Ho, Keith T, Mount, Howard TJ, Sled, John G, Kain, Kevin C

“…Cerebral malaria (CM) is associated with a high mortality rate, and long-term neurocognitive impairment in approximately one third of survivors. Adjunctive…”
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Effects of repeated adolescent stress and serotonin transporter gene partial knockout in mice on behaviors and brain structures relevant to major depression by Spinelli, Simona, Müller, Tanja, Friedel, Miriam, Sigrist, Hannes, Lesch, Klaus-Peter, Henkelman, Mark, Rudin, Markus, Seifritz, Erich, Pryce, Christopher R

“…In humans, exposure to stress during development is associated with structural and functional alterations of the prefrontal cortex (PFC), amygdala (AMY), and…”
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Self-assembly of peptides into a beta-barrel motif by Friedel, Miriam, Shea, Joan-Emma

“…We report the results of a study of the self-assembly of four minimalist peptide strands with a native beta-barrel structure. Using a soft-well potential to…”
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Effects of frustration, confinement, and surface interactions on the dimerization of an off-lattice beta-barrel protein by Griffin, Mary A, Friedel, Miriam, Shea, Joan-Emma

“…We study the effects of confinement, sequence frustration, and surface interactions on the thermodynamics of dimerization of an off-lattice minimalist…”
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PPAR gamma Agonists Improve Survival and Neurocognitive Outcomes in Experimental Cerebral Malaria and Induce Neuroprotective Pathways in Human Malaria: e1003980 by Serghides, Lena, McDonald, Chloe R, Lu, Ziyue, Friedel, Miriam, Cui, Cheryl, Ho, Keith T, Mount, Howard TJ, Sled, John G, Kain, Kevin C

“…Cerebral malaria (CM) is associated with a high mortality rate, and long-term neurocognitive impairment in approximately one third of survivors. Adjunctive…”
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Using molecular dynamics simulations of proteins to understand the effects of confinement by Friedel, Miriam R

“…Although the information necessary for a protein to fold is encoded in its amino acid sequence, the environment in which it folds can have a significant impact…”
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PPAR[gamma] Agonists Improve Survival and Neurocognitive Outcomes in Experimental Cerebral Malaria and Induce Neuroprotective Pathways in Human Malaria by Serghides, Lena, McDonald, Chloe, Lu, Ziyue, Friedel, Miriam, Cui, Cheryl, Ho, Keith, Mount, Howard, Sled, John, Kain, Kevin

“…  Cerebral malaria (CM) is associated with a high mortality rate, and long-term neurocognitive impairment in approximately one third of survivors. Adjunctive…”
Get full text