Search Results - "Fried, Susan"

Modeling mechanisms driving metabolic benefits of time‐restricted eating by Fried, Susan K.

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Adipose ‘neighborhoods’ collaborate to maintain metabolic health by Fried, Susan K

“…Body fat is stored in anatomically distinct adipose depots that vary in their cell composition and play specialized roles in systemic metabolic homeostasis via…”
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Adipose tissue heterogeneity: Implication of depot differences in adipose tissue for obesity complications by Lee, Mi-Jeong, Wu, Yuanyuan, Fried, Susan K.

“…Obesity, defined as excess fat mass, increases risks for multiple metabolic diseases, such as type 2 diabetes, cardiovascular disease and several types of…”
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Cellular Mechanisms Driving Sex Differences in Adipose Tissue Biology and Body Shape in Humans and Mouse Models by Karastergiou, Kalypso, Fried, Susan K

“…Sex differences in adipose tissue distribution and the metabolic, endocrine, and immune functions of different anatomical fat depots have been described, but…”
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Deconstructing the roles of glucocorticoids in adipose tissue biology and the development of central obesity by Lee, Mi-Jeong, Pramyothin, Pornpoj, Karastergiou, Kalypso, Fried, Susan K.

“…Central obesity is associated with insulin resistance and dyslipidemia. Thus, the mechanisms that control fat distribution and its impact on systemic…”
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Sex differences in human adipose tissues - the biology of pear shape by Karastergiou, Kalypso, Smith, Steven R, Greenberg, Andrew S, Fried, Susan K

“…Women have more body fat than men, but in contrast to the deleterious metabolic consequences of the central obesity typical of men, the pear-shaped body fat…”
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Shaping fat distribution: New insights into the molecular determinants of depot‐ and sex‐dependent adipose biology by Fried, Susan K., Lee, Mi‐Jeong, Karastergiou, Kalypso

“…Objective To review recent advances in understanding the cellular mechanisms that regulate fat distribution. Methods In this review, new insights into depot…”
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High-fat diet-induced obesity regulates MMP3 to modulate depot- and sex-dependent adipose expansion in C57BL/6J mice by Wu, Yuanyuan, Lee, Mi-Jeong, Ido, Yasuo, Fried, Susan K

“…Increased adipocyte size is hypothesized to signal the recruitment of adipose progenitor cells (APCs) to expand tissue storage capacity. To investigate depot…”
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Adipose tissue's rapid response team by Fried, Susan K.

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Adipocyte size redux by Fried, Susan K.

“…Laforest et al.'s article reemphasizes adipocyte size as a key obesity phenotype and points to the need to assure the rigor and reproducibility of adipocyte…”
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Metabolic and structural remodeling during browning of primary human adipocytes derived from omental and subcutaneous depots by Lee, Mi‐Jeong, Puri, Vishwajeet, Fried, Susan K.

“…Objective This study investigated remodeling of cellular metabolism and structures during browning of primary human adipocytes derived from both visceral and…”
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l-Arginine supplementation regulates energy-substrate metabolism in skeletal muscle and adipose tissue of diet-induced obese rats by Jobgen, Wenjuan S, Lee, Mi-Jeong, Fried, Susan K, Wu, Guoyao

“…Dietary supplementation with l-arginine has been reported to reduce white fat mass in diet-induced obese rats and in obese humans. This study was conducted to…”
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Adipose tissue remodeling in pathophysiology of obesity by Lee, Mi-Jeong, Wu, Yuanyuan, Fried, Susan K

“…PURPOSE OF REVIEWRecent studies demonstrate that adipose tissue undergoes a continuous process of remodeling that is pathologically accelerated in the obese…”
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Identification of a novel lncRNA in gluteal adipose tissue and evidence for its positive effect on preadipocyte differentiation by Divoux, Adeline, Karastergiou, Kalypso, Xie, Hui, Guo, Weimen, Perera, Ranjan J., Fried, Susan K., Smith, Steven R.

“…Objective Peripheral lower body fat is associated with lower cardiometabolic risk. Physiological differences in gluteal compared with abdominal subcutaneous…”
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Rosiglitazone remodels the lipid droplet and britens human visceral and subcutaneous adipocytes ex vivo[S] by Lee, Mi-Jeong, Jash, Sukanta, Jones, Jessica E.C., Puri, Vishwajeet, Fried, Susan K.

“…Treatment with PPARγ agonists in vivo improves human adipocyte metabolism, but the cellular mechanisms and possible depot differences in responsiveness to…”
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Distinct Developmental Signatures of Human Abdominal and Gluteal Subcutaneous Adipose Tissue Depots by Karastergiou, Kalypso, Fried, Susan K, Xie, Hui, Lee, Mi-Jeong, Divoux, Adeline, Rosencrantz, Marcus A, Chang, R. Jeffrey, Smith, Steven R

“…Context: Fat distribution differs in men and women, but in both sexes, a predominantly gluteal-femoral compared with abdominal (central) fat distribution is…”
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miR-130 Suppresses Adipogenesis by Inhibiting Peroxisome Proliferator-Activated Receptor γ Expression by Lee, Eun Kyung, Lee, Mi Jeong, Abdelmohsen, Kotb, Kim, Wook, Kim, Mihee M., Srikantan, Subramanya, Martindale, Jennifer L., Hutchison, Emmette R., Kim, Hyeon Ho, Marasa, Bernard S., Selimyan, Roza, Egan, Josephine M., Smith, Steven R., Fried, Susan K., Gorospe, Myriam

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Liver Fatty Acid‐Binding Protein (LFABP) Ablation Drives Hyperplastic Expansion of Subcutaneous Adipose Tissue in Male Mice Fed High‐Fat Diet by Diolintzi, Anastasia, Zhou, YinXiu, Fried, Susan K., Polunas, Marianne, Sidossis, Labros S., Storch, Judith

“…Liver fatty acid‐binding protein (LFABP) functions both in intracellular lipid trafficking in liver and small intestine, and in systemic energy homeostasis…”
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Vitamin D Inhibits Adipokine Production and Inflammatory Signaling Through the Vitamin D Receptor in Human Adipocytes by Nimitphong, Hataikarn, Guo, Weimin, Holick, Michael F., Fried, Susan K., Lee, Mi‐Jeong

“…Objective The purpose of this study was to investigate the effects of vitamin D on adipokine expression and inflammation in human adipose tissues and…”
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Aortic carboxypeptidase-like protein enhances adipose tissue stromal progenitor differentiation into myofibroblasts and is upregulated in fibrotic white adipose tissue by Jager, Mike, Lee, Mi-Jeong, Li, Chendi, Farmer, Stephen R, Fried, Susan K, Layne, Matthew D

“…White adipose tissue expands through both adipocyte hypertrophy and hyperplasia and it is hypothesized that fibrosis or excess accumulation of extracellular…”
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