Search Results - "Friebel, Tara"

Modifiers of Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: A Systematic Review and Meta-Analysis by FRIEBEL, Tara M, DOMCHEK, Susan M, REBBECK, Timothy R

“…There is substantial variability in cancer risk in women who have inherited a BRCA1 or BRCA2 (BRCA1/2) mutation. Numerous factors have been hypothesized to…”
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Association of Risk-Reducing Surgery in BRCA1 or BRCA2 Mutation Carriers With Cancer Risk and Mortality by Domchek, Susan M, Friebel, Tara M, Singer, Christian F, Evans, D. Gareth, Lynch, Henry T, Isaacs, Claudine, Garber, Judy E, Neuhausen, Susan L, Matloff, Ellen, Eeles, Rosalind, Pichert, Gabriella, Van t’veer, Laura, Tung, Nadine, Weitzel, Jeffrey N, Couch, Fergus J, Rubinstein, Wendy S, Ganz, Patricia A, Daly, Mary B, Olopade, Olufunmilayo I, Tomlinson, Gail, Schildkraut, Joellen, Blum, Joanne L, Rebbeck, Timothy R

“…CONTEXT Mastectomy and salpingo-oophorectomy are widely used by carriers of BRCA1 or BRCA2 mutations to reduce their risks of breast and ovarian cancer…”
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Risk-Reducing Salpingo-Oophorectomy for the Prevention of BRCA1- and BRCA2-Associated Breast and Gynecologic Cancer: A Multicenter, Prospective Study by KAUFF, Noah D, DOMCHEK, Susan M, NEUHAUSEN, Susan L, DALY, Mary B, MATLOFF, Ellen, BLUM, Joanne L, SABBATINI, Paul, BARAKAT, Richard R, HUDIS, Clifford, NORTON, Larry, OFFIT, Kenneth, REBBECK, Timothy R, FRIEBEL, Tara M, ROBSON, Mark E, LEE, Johanna, GARBER, Judy E, ISAACS, Claudine, EVANS, D. Gareth, LYNCH, Henry, EELES, Rosalind A

“…Risk-reducing salpingo-oophorectomy (RRSO) has been widely adopted as a key component of breast and gynecologic cancer risk-reduction for women with BRCA1 and…”
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Relationship of established risk factors with breast cancer subtypes by McCarthy, Anne Marie, Friebel‐Klingner, Tara, Ehsan, Sarah, He, Wei, Welch, Michaela, Chen, Jinbo, Kontos, Despina, Domchek, Susan M., Conant, Emily F., Semine, Alan, Hughes, Kevin, Bardia, Aditya, Lehman, Constance, Armstrong, Katrina

“…Background Breast cancer is a heterogeneous disease, divided into subtypes based on the expression of estrogen receptor (ER), progesterone receptor (PR), and…”
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The spectrum of BRCA1 and BRCA2 pathogenic sequence variants in Middle Eastern, North African, and South European countries by Laitman, Yael, Friebel, Tara M., Yannoukakos, Drakoulis, Fostira, Florentia, Konstantopoulou, Irene, Figlioli, Gisella, Bonanni, Bernardo, Manoukian, Siranoush, Zuradelli, Monica, Tondini, Carlo, Pasini, Barbara, Peterlongo, Paolo, Plaseska‐Karanfilska, Dijana, Jakimovska, Milena, Majidzadeh, Keivan, Zarinfam, Shiva, Loizidou, Maria A., Hadjisavvas, Andreas, Michailidou, Kyriaki, Kyriacou, Kyriacos, Behar, Doron M., Molho, Rinat Bernstein, Ganz, Patricia, James, Paul, Parsons, Michael T., Sallam, Aminah, Olopade, Olufunmilayo I., Seth, Arun, Chenevix ‐ Trench, Georgia, Leslie, Goska, McGuffog, Lesley, Marafie, Makia J, Megarbane, Andre, Al‐Mulla, Fahd, Rebbeck, Timothy R., Friedman, Eitan

“…BRCA1 BRCA2 mutational spectrum in the Middle East, North Africa, and Southern Europe is not well characterized. The unique history and cultural practices…”
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Evaluating the geographic distribution of cervical cancer patients presenting to a multidisciplinary gynecologic oncology clinic in Gaborone, Botswana by Friebel-Klingner, Tara M, Iyer, Hari S, Ramogola-Masire, Doreen, Bazzett-Matabele, Lisa, Monare, Barati, Seiphetlheng, Alexander, Ralefala, Tlotlo B, Mitra, Nandita, Wiebe, Douglas J, Rebbeck, Timothy R, Grover, Surbhi, McCarthy, Anne Marie

“…In Botswana, cervical cancer is the leading cause of cancer death for females. With limited resources, Botswana is challenged to ensure equitable access to…”
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Uterine Cancer After Risk-Reducing Salpingo-oophorectomy Without Hysterectomy in Women With BRCA Mutations by Shu, Catherine A, Pike, Malcolm C, Jotwani, Anjali R, Friebel, Tara M, Soslow, Robert A, Levine, Douglas A, Nathanson, Katherine L, Konner, Jason A, Arnold, Angela G, Bogomolniy, Faina, Dao, Fanny, Olvera, Narciso, Bancroft, Elizabeth K, Goldfrank, Deborah J, Stadler, Zsofia K, Robson, Mark E, Brown, Carol L, Leitao, Jr, Mario M, Abu-Rustum, Nadeem R, Aghajanian, Carol A, Blum, Joanne L, Neuhausen, Susan L, Garber, Judy E, Daly, Mary B, Isaacs, Claudine, Eeles, Rosalind A, Ganz, Patricia A, Barakat, Richard R, Offit, Kenneth, Domchek, Susan M, Rebbeck, Timothy R, Kauff, Noah D

“…The link between BRCA mutations and uterine cancer is unclear. Therefore, although risk-reducing salpingo-oophorectomy (RRSO) is standard treatment among women…”
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BRCA1 and BRCA2 pathogenic sequence variants in women of African origin or ancestry by Friebel, Tara M., Andrulis, Irene L., Balmaña, Judith, Blanco, Amie M., Couch, Fergus J., Daly, Mary B., Domchek, Susan M., Easton, Douglas F., Foulkes, William D., Ganz, Patricia A., Garber, Judy, Glendon, Gord, Greene, Mark H., Hulick, Peter J., Isaacs, Claudine, Jankowitz, Rachel C., Karlan, Beth Y., Kirk, Judy, Kwong, Ava, Lee, Annette, Lesueur, Fabienne, Lu, Karen H., Nathanson, Katherine L., Neuhausen, Susan L., Offit, Kenneth, Palmero, Edenir I., Sharma, Priyanka, Tischkowitz, Marc, Toland, Amanda E., Tung, Nadine, Rensburg, Elizabeth J., Vega, Ana, Weitzel, Jeffrey N., Collaborators, GEMO Study, Hoskins, Kent F., Maga, Tara, Parsons, Michael T., McGuffog, Lesley, Antoniou, Antonis C., Chenevix‐Trench, Georgia, Huo, Dezheng, Olopade, Olufunmilayo I., Rebbeck, Timothy R.

“…BRCA1 and BRCA2 (BRCA1/2) pathogenic sequence variants (PSVs) confer elevated risks of multiple cancers. However, most BRCA1/2 PSVs reports focus on European…”
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Use of risk-reducing surgeries in a prospective cohort of 1,499 BRCA1 and BRCA2 mutation carriers by Chai, Xinglei, Friebel, Tara M., Singer, Christian F., Evans, D. Gareth, Lynch, Henry T., Isaacs, Claudine, Garber, Judy E., Neuhausen, Susan L., Matloff, Ellen, Eeles, Rosalind, Tung, Nadine, Weitzel, Jeffrey N., Couch, Fergus J., Hulick, Peter J., Ganz, Patricia A., Daly, Mary B., Olopade, Olufunmilayo I., Tomlinson, Gail, Blum, Joanne L., Domchek, Susan M., Chen, Jinbo, Rebbeck, Timothy R.

“…Inherited mutations in BRCA1 or BRCA2 ( BRCA1/2 ) confer very high risk of breast and ovarian cancers. Genetic testing and counseling can reduce risk and death…”
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Mortality after bilateral salpingo-oophorectomy in BRCA1 and BRCA2 mutation carriers: a prospective cohort study by Domchek, Susan M, Friebel, Tara M, Neuhausen, Susan L, Wagner, Theresa, Evans, Gareth, Isaacs, Claudine, Garber, Judy E, Daly, Mary B, Eeles, Rosalind, Matloff, Ellen, Tomlinson, Gail E, Van't Veer, Laura, Lynch, Henry T, Olopade, Olufunmilayo I, Weber, Barbara L, Rebbeck, Timothy R

“…Bilateral prophylactic salpingo-oophorectomy (BPSO) is used widely used to reduce the risk of breast and ovarian cancer in women with BRCA1 and BRCA2…”
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Bilateral Prophylactic Mastectomy Reduces Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: The PROSE Study Group by REBBECK, Timothy R, FRIEBEL, Tara, DALY, Mary B, OLOPADE, Olufunmilayo I, WEBER, Barbara L, LYNCH, Henry T, NEUHAUSEN, Susan L, VAN'T VEER, Laura, GARBER, Judy E, EVANS, Gareth R, NAROD, Steven A, ISAACS, Claudine, MATLOFF, Ellen

“…Data on the efficacy of bilateral prophylactic mastectomy for breast cancer risk reduction in women with BRCA1 and BRCA2 (BRCA1/2) mutations are limited,…”
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Clinical and sociodemographic factors associated with late stage cervical cancer diagnosis in Botswana by Friebel-Klingner, Tara M, Luckett, Rebecca, Bazzett-Matabele, Lisa, Ralefala, Tlotlo B, Monare, Barati, Nassali, Mercy Nkuba, Ramogola-Masire, Doreen, Bvochora, Memory, Mitra, Nandita, Wiebe, Douglas, Rebbeck, Timothy R, McCarthy, Anne Marie, Grover, Surbhi

“…Cervical cancer is the leading cause of female cancer mortality in Botswana with the majority of cervical cancer patients presenting with late-stage disease…”
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Effect of Short-Term Hormone Replacement Therapy on Breast Cancer Risk Reduction After Bilateral Prophylactic Oophorectomy in BRCA1 and BRCA2 Mutation Carriers: The PROSE Study Group by REBBECK, Timothy R, FRIEBEL, Tara, EELES, Rosalind, EVANS, D. Gareth, TOMLINSON, Gail, MATLOFF, Ellen, NAROD, Steven A, EISEN, Andrea, DOMCHEK, Susan, ARMSTRONG, Katrma, WEBER, Barbara L, WAGNER, Theresa, LYNCH, Henry T, GARBER, Judy E, DALY, Mary B, ISAACS, Claudine, OLOPADE, Olufunmilayo I, NEUHAUSEN, Susan L, VAN 'T VEER, Laura

“…Bilateral prophylactic oophorectomy (BPO) is widely used for cancer risk reduction in women with BRCA1/2 mutations. Many premenopausal women choose to take…”
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Patient perspectives on delays in cervical cancer screening and follow-up care in Botswana: a mixed methods study by Rendle, Katharine A, Ramogola-Masire, Doreen, Monare, Barati, Ogden, Shannon N, Toneff, Hannah K, Saia, Chelsea A, Wainwright, Jocelyn V, Friebel-Klingner, Tara M, Bazzett-Matabele, Lisa, Bhatia, Rohini, Bonner, Natalie, Ralefala, Tlotlo B, Vuylsteke, Peter, Luckett, Rebecca, Grover, Surbhi

“…Delays in screening and timely diagnosis contribute significantly to global disparities in cervical cancer mortality in Botswana and other low- and…”
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Characterization of BRCA1 and BRCA2 Mutations in a Large United States Sample by SINING CHEN, IVERSEN, Edwin S, CORIO, Camille, LEONDARIDIS, Leoni, TOMLINSON, Gail, DUTSON, Debra, KERBER, Rich, AMOS, Christopher I, STRONG, Louise C, BERRY, Donald A, EUHUS, David M, PARMIGIANI, Giovanni, FRIEBEL, Tara, FINKELSTEIN, Dianne, WEBER, Barbara L, EISEN, Andrea, PETERSON, Leif E, SCHILDKRAUT, Joellen M, ISAACS, Claudine, PESHKIN, Beth N

“…An accurate evaluation of the penetrance of BRCA1 and BRCA2 mutations is essential to the identification and clinical management of families at high risk of…”
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Expanding Geographical Access to Cancer Care in Botswana: Current Status and Future Prospects by Swart, Norman C, Lebelonyane, Refeletswe, Gutterman, Elane M, Legwaila, Morongwa, Friebel-Klingner, Tara M, Antony, Reena, Mayer, Tina, Sharma, Kirthana, Lall, Naveena, Kania, Brooke, Gaolathe, Tendani, Ralefala, Tlotlo, Ndaba, Vusikhaya, Leselwa, Tapologo, Vuylsteke, Peter, Marlink, Richard

“…The growing cancer burden in Botswana has been linked to aging, lifestyle factors, and high HIV infection prevalence. The government has designated four…”
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State of the Science of Scale-Up of Cancer Prevention and Early Detection Interventions in Low- and Middle-Income Countries: A Scoping Review by Friebel-Klingner, Tara M, Alvarez, Gloria Guevara, Lappen, Hope, Pace, Lydia E, Huang, Keng-Yen, Fernández, Maria E, Shelley, Donna, Rositch, Anne F

“…Cancer deaths in low- and middle-income countries (LMICs) will nearly double by 2040. Available evidence-based interventions (EBIs) for cancer prevention and…”
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Cervical cancer screening in HIV-endemic countries: An urgent call for guideline change by Grover, Surbhi, Bhatia, Rohini, Friebel-Klingner, Tara M., Mathoma, Anikie, Vuylsteke, Peter, Khan, Salman, Ralefala, Tlotlo, Tawe, Leabaneng, Bazzett-Matabele, Lisa, Monare, Barati, Luckett, Rebecca, Ramogola-Masire, Doreen

“…•In Botswana, median age of cervical cancer diagnosis for women living with HIV was 47.9.•Among women living without HIV, median age at cervical cancer…”
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Breast and Ovarian Cancer Risk and Risk Reduction in Jewish BRCA1/2 Mutation Carriers by FINKELMAN, Brian S, RUBINSTEIN, Wendy S, OLOPADE, Olufunmilayo I, WEITZEL, Jeffrey N, LYNCH, Henry T, SNYDER, Carrie, GARBER, Judy E, SCHILDKRAUT, Joellen, DALY, Mary B, ISAACS, Claudine, PICHERT, Gabrielle, NEUHAUSEN, Susan L, FRIEDMAN, Sue, COUCH, Fergus J, VEER, Laura Van't, EELES, Rosalind, BANCROFT, Elizabeth, GARETH EVANS, D, GANZ, Patricia A, TOMLINSON, Gail E, NAROD, Steven A, MATLOFF, Ellen, DOMCHEK, Susan, FRIEBEL, Tara M, REBBECK, Timothy R, DUBITSKY, Shera, SINGER SCHONBERGER, Niecee, SHORETZ, Rochelle, SINGER, Christian F, BLUM, Joanne L, TUNG, Nadine

“…Mutations in BRCA1/2 dramatically increase the risk of both breast and ovarian cancers. Three mutations in these genes (185delAG, 5382insC, and 6174delT) occur…”
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Cascade Analysis for Women Presenting With Breast Concerns to a Zonal Hospital in Mwanza, Tanzania by Friebel-Klingner, Tara M, Joo, Emma, Kirahi, Matogoro, Pace, Lydia E, Platz, Elizabeth A, Masalu, Nestory, Washington, Leonard, Rositch, Anne F

“…In Tanzania, high breast cancer mortality can be attributed to delays in diagnosis and treatment initiation. We adapted the cascade analysis method to depict…”
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