Search Results - "Fridrichova, I"

416: DNA methylation profiles in invasive breast tumours associate with methylation in lymph node metastases and not in plasma samples by Fridrichova, I, Zmetakova, I, Kajabova, V, Mego, M, Cierna, Z, Krivulcik, T, Smolkova, B

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Evaluation of protein expression and DNA methylation profiles detected by pyrosequencing in invasive breast cancer by Zmetakova, I, Danihel, L, Smolkova, B, Mego, M, Kajabova, V, Krivulcik, T, Rusnak, I, Rychly, B, Danis, D, Repiska, V, Blasko, P, Karaba, M, Benca, J, Pechan, J, Fridrichova, I

“…Breast carcinoma is the most common cancer with high mortality caused by metastatic disease. New molecular biomarkers predicting the tumour's metastatic…”
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Global and gene specific DNA methylation in breast cancer cells was not affected during epithelial-to-mesenchymal transition in vitro by Smolkova, B, Miklikova, S, Kajabova, V Horvathova, Babelova, A, Yamani, N El, Zduriencikova, M, Fridrichova, I, Zmetakova, I, Krivulcik, T, Kalinkova, L, Matuskova, M, Kucerova, L, Dusinska, M

“…Epithelial-to-mesenchymal transition (EMT) significantly affects the risk of metastasising in breast cancer. Plasticity and reversibility of EMT suggest that…”
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534 Epigenetic Changes in Tumour Tissue and Plasma DNA Samples From Breast Cancer Patients by Fridrichova, I, Kajabova, V, Zmetakova, I, Bella, V, Kajo, K, Machalekova, K, Sebova, K, Krivulcik, T, Stankovicova, I, Smolkova, B

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PO-394 DNA methylation of ADAM23 is negatively associated with haematogenous spread in breast cancer by Smolkova, B, Mego, M, Zmetakova, I, Kajabova, V Horvathova, Miklikova, S, Kalinkova, L, Minarik, G, Sedlackova, T, Cierna, Z, Fridrichova, I

“…IntroductionCirculating tumour cells (CTCs) are associated with metastatic potential in a variety of human cancers. Although DNA methylation of cancer-related…”
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DNA methylation profiles in colorectal cancers of Lynch-syndrome patients by Fridrichova, I, Sebova, K, Alemayehu, A

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The role of clinical criteria, genetic and epigenetic alterations in Lynch-syndrome diagnosis by Alemayehu, A, Tomkova, K, Zavodna, K, Ventusova, K, Krivulcik, T, Bujalkova, M, Bartosova, Z, Fridrichova, I

“…Lynch syndrome (hereditary nonpolyposis colorectal cancer, HNPCC) represents 1-3% of all diagnosed colorectal cancers (CRCs). This study aimed to evaluate the…”
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Novel and recurrent germline alterations in the MLH1 and MSH2 genes identified in hereditary nonpolyposis colorectal cancer patients in Slovakia by Zavodna, K, Bujalkova, M, Krivulcik, T, Alemayehu, A, Skorvaga, M, Marra, G, Fridrichova, I, Jiricny, J, Bartosova, Z

“…Hereditary non-polyposis colorectal cancer (HNPCC) is associated with germline mutations in DNA mismatch repair genes, predominantly MSH2 and MLH1. Mutation…”
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Epigenetic tools in potential anticancer therapy by Sebova, Katarina, Fridrichova, Ivana

“…Human cancer represents a heterogeneous group of diseases that are driven by progressive genetic and epigenetic abnormalities. The latter alterations involve…”
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Cytogenetic study of blood in women who had used oral contraceptives by FRIDRICHOVA, I

“…Changes in the number and structure of chromosomes in peripheral lymphocytes of 31 healthy women using oral contraceptives (OC) were studied. Blood samples…”
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Approaches to identification of HNPCC suspected patients in Slovak population by Fridrichová, I, Ilencíková, D, Friedl, W, Hlavcák, P, Skorvaga, M, Krizan, P, Pálaj, J, Pirsel, M, Farkasová, E, Bartosová, Z

“…Patients with hereditary non-polyposis colorectal cancer (HNPCC) have a DNA mismatch repair defect (MMR) in their tumor tissue that results in instability of…”
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Abstract P1-04-02: Correlation between blood markers of hemostasis and circulating tumor cells (CTCs) in early breast cancer patients by Mego, M, Karaba, M, Minarik, G, Benca, J, Sedlackova, T, Tothova, L, Vlkova, B, Cierna, Z, Janega, P, Manasova, D, Luha, J, Gronesova, P, Pechan, J, Fridrichova, I, Celec, P, Reuben, JM, Cristofanilli, M, Mardiak, J

“…Abstract Background: Cancer is a risk factor for venous thromboembolism (VTE) and plasma D-dimer (DD) and tissue factor (TF) are established blood markers…”
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DNA repair in Escherichia coli: the dual function of uvr genes by Masek, F, Fridrichova, I, Pirsel, M, Sedliaková, M

“…It has been shown earlier that the starvation of E. coli for both amino-acids and thymine applied prior to UV irradiation inhibits pyrimidine dimer excision…”
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Expression of the Escherichia coli recA gene in the yeast Saccharomyces cerevisiae by Cernakova, L, Fridrichova, I, Pirsel, M, Kleibl, K, Duraj, J, Brozmanova, J

“…The isolation of the protein coding region of the recA gene from Escherichia coli by extensive Bal31 digestion is described. The structural recA gene was…”
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The Escherichia coli recA gene increases resistance of the yeast Saccharomyces cerevisiae to ionizing and ultraviolet radiation by Brozmanová, J, Cernáková, L, Vlcková, V, Duraj, J, Fridrichová, I

“…The Escherichia coli recA protein coding region was ligated into an extrachromosomally replicating yeast expression vector downstream of the yeast alcohol…”
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Constitutive increase of RecA protein : its influence on pyrimidine dimer excision and survival of UV-irradiated Escherichia coli by SLEZARIKOVA, V, MASEK, F, FRIDRICHOVA, I, PIRSEL, M, SEDLIAKOVA, M

“…Transformation of E. coli with the plasmid pRA containing recA gene increased the constitutive level of RecA protein 50-67 fold. This slightly inhibited…”
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Inhibition of dimer excision in repeatedly UV-irradiated Escherichia coli: its requirement for RecA protein and de novo protein synthesis by Fridrichová, I, Kleibl, K, Masek, F, Sedliaková, M

“…In UV-irradiated Escherichia coli dimer excision was found to be inhibited by predamage (M. Sedliaková, F. Masek and J. Brozmanová, FEBS Lett., 23 (1972)…”
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Effect of bacterial recA expression on DNA repair in the rad51 and rad52 mutants of Saccharomyces cerevisiae by Morais Jr, M.A., Vlcková, V., Fridrichová, I., Slaninová, M., Brozmanová, J., Henriques, J.A.P.

“…Molecular and functional homology between yeast proteins pRad51 and pRad52 and Escherichia coli pRecA involved in recombinational DNA repair led us to…”
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Searching for a functional analogy between yeast Pso4 and bacterial RecA proteins in induced mitotic recombination by Vlcková, V, Slaninová, M, Morais, Jr, M A, Henriques, J A, Fridrichová, I, Brozmanová, J

“…The pso4-1 mutant of S. cerevisiae is phenotypically similar to the recA mutant of E. coli; it is sensitive to DNA cross-linking agents and defective in both…”
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Immunological quantification of RecA protein in cell extracts of E. coli after exposure to chemical mutagens or UV radiation by FRIDRICHOVA, I, KOVARIK, A, ROSSKOPFOVA, O

“…Increased synthesis of RecA protein is induced in E. coli cells after their damage, the rate of synthesis being dependent on the extent of DNA alterations. The…”
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