Search Results - "Fridmanis, D"

Genetic characterization of the Latvian local goat breed and genetic traits associated with somatic cell count by Gudra, D., Valdovska, A., Jonkus, D., Kairisa, D., Galina, D., Ustinova, M., Viksne, K., Fridmanis, D., Kalnina, I.

“…•Population analysis confirmed the genetic differentiation of the Latvian local goat.•Historical crossbreeding has left a substantial imprint on the Latvian…”
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Control of Acinetobacter baumannii outbreak in the neonatal intensive care unit in Latvia: whole-genome sequencing powered investigation and closure of the ward by Gramatniece, A, Silamikelis, I, Zahare, Ie, Urtans, V, Zahare, Ir, Dimina, E, Saule, M, Balode, A, Radovica-Spalvina, I, Klovins, J, Fridmanis, D, Dumpis, U

“…is an emerging pathogen capable of causing hospital-acquired infections (HAIs). It has the ability to survive on environmental surfaces for months, making…”
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Stronger association of common variants in TCF7L2 gene with nonobese type 2 diabetes in the Latvian population by Kalnina, I, Geldnere, K, Tarasova, L, Nikitina-Zake, L, Peculis, R, Fridmanis, D, Pirags, V, Klovins, J

“…Polymorphisms in the gene coding for transcription factor 7 like 2 (TCF7L2) are recognized as the strongest common genetic risk factors for type 2 diabetes…”
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P-347 Gastrointestinal microbiome association with health status in Latvian population reveals significant shifts in gastrointestinal cancer patients at taxonomical and functional level by Ustinova, M., Gudra, D., Vangravs, R., Polaka, I., Leja, M., Fridmanis, D.

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Association between CETP, MLXIPL, and TOMM40 polymorphisms and serum lipid levels in a Latvian population by Radovica, I., Fridmanis, D., Silamikelis, I., Nikitina-Zake, L., Klovins, J.

“…Abnormal lipid levels are considered one of the most significant risk factors for atherosclerosis and coronary artery disease, two of the main causes of death…”
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Replacement of short segments within transmembrane domains of MC2R disrupts retention signal by Fridmanis, Davids, Petrovska, Ramona, Pjanova, Dace, Schiöth, Helgi B, Klovins, Janis

“…The proteolysis of the pro-opiomelanocortin precursor results in the formation of melanocortins (MCs), a group of peptides that share the conserved -H-F-R-W-…”
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The melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRs by Klovins, Janis, Haitina, Tatjana, Fridmanis, Davids, Kilianova, Zuzana, Kapa, Ivo, Fredriksson, Robert, Gallo-Payet, Nicole, Schiöth, Helgi B

“…The G-protein-coupled melanocortin receptors (MCRs) play an important role in a variety of essential functions such as the regulation of pigmentation, energy…”
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FIT test-systems for mega-scale gut microbiome testing by Gudra, D, Fridmanis, D, Klovins, J, Skenders, G, Silamikelis, I, Radovica-Spalvina, I, Peculis, R, Kalnina, I, Elbere, I, Hultcrantz, R, Leja, M, Engstrand, L

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Cloning of two melanocortin (MC) receptors in spiny dogfish: MC3 receptor in cartilaginous fish shows high affinity to ACTH-derived peptides while it has lower preference to gamma-MSH by Klovins, Janis, Haitina, Tatjana, Ringholm, Aneta, Löwgren, Maja, Fridmanis, Davids, Slaidina, Maija, Stier, Susanne, Schiöth, Helgi B

“…We report the cloning and characterization of two melanocortin receptors (MCRs) from the spiny dogfish (Squalus acanthias) (Sac). Phylogenetic analysis shows…”
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High Affinity Agonistic Metal Ion Binding Sites within the Melanocortin 4 Receptor Illustrate Conformational Change of Transmembrane Region 3 by Lagerström, Malin C., Klovins, Janis, Fredriksson, Robert, Fridmanis, Davids, Haitina, Tatjana, Ling, Maria K., Berglund, Magnus M., Schiöth, Helgi B.

“…We created a molecular model of the human melanocortin 4 receptor (MC4R) and introduced a series of His residues into the receptor protein to form metal ion…”
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Origin of the prolactin-releasing hormone (PRLH) receptors: Evidence of coevolution between PRLH and a redundant neuropeptide Y receptor during vertebrate evolution by Lagerström, Malin C., Fredriksson, Robert, Bjarnadóttir, Thóra K., Fridmanis, Davids, Holmquist, Tomas, Andersson, Jan, Yan, Yi-Lin, Raudsepp, Terje, Zoorob, Rima, Kukkonen, Jyrki P., Lundin, Lars-Gustav, Klovins, Janis, Chowdhary, Bhanu P., Postlethwait, John H., Schiöth, Helgi B.

“…We present seven new vertebrate homologs of the prolactin-releasing hormone receptor (PRLHR) and show that these are found as two separate subtypes, PRLHR1 and…”
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Unusual Genomic Structure: Melanocortin Receptors in Fugu by SCHIÖTH, HELGI B., HAITINA, TATJANA, FRIDMANIS, DAVIDS, KLOVINS, JANIS

“…: The melanocortin (MC) receptors are found in five subtypes in mammals and chicken, while recent studies have shown that the Fugu (Takifugu rubripes) genome…”
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